NUMERICAL SIMULATION OF TRANSIENT BLOOD FLOW THROUGH THE LEFT CORONARY ARTERY WITH VARYING DEGREES OF BIFURCATION ANGLES

2017 ◽  
Vol 17 (01) ◽  
pp. 1750005
Author(s):  
BO ZHANG ◽  
YILUN JIN ◽  
XIAORAN WANG ◽  
TAISHENG ZENG ◽  
LIANSHENG WANG
Keyword(s):  
Blood Flow ◽  
Coronary Artery ◽  
Left Coronary Artery ◽  
Vascular System ◽  
Abdominal Aortic ◽  
Analysis Technique ◽  
Common Technique ◽  
Computational Fluid Dynamics Cfd ◽  
Flow Through ◽  
The Relationship

Atherosclerosis is a cardiovascular condition that can occur in any part of the vascular system. Especially, it can exist in bifurcated arteries such as the left and right coronary arteries, abdominal aortic bifurcation or carotid artery bifurcation. In our study, we examine the left coronary artery as an exemplification using wall shear stress (WSS) and wall pressure gradient (WPG). Then, we attempt to find the relationship between bifurcated arterial geometry and hemodynamics. Computational fluid dynamics (CFD) is a common technique applied to characterize blood flow accurately and assist us to gain an insight of atherosclerosis. In this paper, we used CFD as the computational hemodynamics analysis technique to examine flow through the left coronary artery that has variable angular bifurcation. Our results demonstrated that the region of low WSS area and magnitudes of maximum WPG increases with the angles of bifurcation. Such hemodynamic condition resulting from the large bifurcation angles has an effect on atherogenesis and is worthy of investigation for better understanding of atherosclerosis.

scholarly journals The Influence of Non-Newtonian Model on Properties of Blood Flow Through a Left Coronary Artery with Presence of Different Double Stenosis

2021 ◽  
Vol 39 (3) ◽  
pp. 895-905
Author(s):  
Saleem K. Kadhim ◽  
Mohammed G. Al-Azawy ◽  
Sinan Abdul-Ghafar Ali ◽  
Mina Qays Kadhim
Keyword(s):  
Blood Flow ◽  
Coronary Artery ◽  
Left Coronary Artery ◽  
Calculated Data ◽  
Shear Stresses ◽  
Numerical Investigations ◽  
Newtonian Model ◽  
Flow Through ◽  
Wall Shear ◽  
Flow States

Cardiovascular diseases were the main cause for loosing lives in the last decades due to the restricted blood flow states in the blood vessels areas. Numerical investigations have been conducted as the aim of this work to examine the blood flow, and wall shear stresses adjacent to the mono stenosis up to different degrees involved in the main, side and distal main branches as well as observe the pulsatile flow of blood in the left coronary artery through various percentage of stenosis. Both the Carreau non-Newtonian rheological model and the Newtonian model were utilized to model the blood fluid and wall shear stresses of left coronary artery, in a row, all the calculated data were validated with the previously published papers. It was found that the blood flow inside areas of the artery lie within the range of non-Newtonian rheological effects can be present, verifying the need to treat blood as non-Newtonian fluid; especially, with the case of 90% blockage.

scholarly journals 3D Transient CFD Modelling of Blood Flow through Coronary Artery

2019 ◽  
Vol 9 (2) ◽  
pp. 1335-1340
Keyword(s):  
Blood Flow ◽  
Coronary Artery ◽  
Vascular System ◽  
Hemodynamic Parameters ◽  
Cfd Modelling ◽  
The Past ◽  
Diastolic Phase ◽  
Flow Through ◽  
Artery Disease ◽  
The Many

Over the past few decades, stroke has become one of the most common cause deaths. The heart muscle, like every other organ or tissue in our body, needs oxygen-rich blood to survive. Coronary artery disease means narrowing of the coronary arteries. This narrowing is due to a buildup of plaque in the walls of the arteries. Computational simulations provide invaluable information that is extremely difficult to obtain experimentally and is one of the many CFD sample applications in the biomedical area in which blood flow through an abnormal artery can be predicted. CFD analysis is increasingly performed to study fluid phenomena inside the human vascular system. In this paper, the study is to develop 3D CFD model of the Coronary artery to observe the blood flow through artery and estimate some of the hemodynamic parameters of blood during systolic and diastolic phase with plaque formation in artery. Hemodynamic parameters were quantified and flow patterns are visualized in the presence of plaques by using CFD.

BLOOD FLOW IN THE CIRCUMFLEX BRANCH OF THE LEFT CORONARY ARTERY OF THE INTACT DOG

1936 ◽  
Vol 117 (2) ◽  
pp. 271-279 ◽  
Author(s):  
Hiram E. Essex ◽  
J. F. Herrick ◽  
Edward J. Baldes ◽  
Frank C. Mann
Keyword(s):  
Blood Flow ◽  
Coronary Artery ◽  
Left Coronary Artery

Simultaneous counting of 85Kr in lung and myocardium during measurement of coronary blood flow

1975 ◽  
Vol 39 (5) ◽  
pp. 788-795
Author(s):  
F. L. Belloni ◽  
D. E. Mohrman ◽  
H. V. Sparks
Keyword(s):  
Mathematical Model ◽  
Blood Flow ◽  
Coronary Artery ◽  
Coronary Blood Flow ◽  
Relative Efficiency ◽  
Left Coronary Artery ◽  
Blood Flow Rate ◽  
Simple Mathematical Model ◽  
Pump Flow ◽  
Best Fitting

Coronary blood flow rate (ml-min-1–100 g-1) was estimated by a) measuring pump flow into the cannulated circumflex branch of the left coronary artery and dividing by the weight of perfused myocardium and b) measuring the clearance of 85Kr following intra-arterial injection (detection with a 2-in. crystal with cylindrical collimation). Although the correlation between the two measurements was relatively high (r equals 0.90), the line best fitting the data was 85Kr flow equals 0.55 pump flow + 25.6. We tested the possibility that the discrepancy between the two methods was primarily due to the counting of 85Kr removed from myocardium and delivered to lung. Relative efficiency of lung counting versus myocardial counting was determined as well as clearance pattern of 85Kr from lung in each dog. A simple mathematical model which assumes no recirculation of 85Kr to heart allowed correction of coronary clearance curves using this information. When corrected 85Kr flow equals 1.00 pump flow + 4.1 (r equals 0.90). Thus, the major systematic cause for the discrepancy between the two measurements under the conditions of this experiment appears to be simultaneous counting of 85Kr in lung and in myocardium.

CFD Analysis Comparing Steady Flow and Pulsatile Flow Through the Aorta and its Main Branches

2016 ◽  
Author(s):  
John D. Martin
Keyword(s):  
Blood Flow ◽  
Steady Flow ◽  
Pulsatile Flow ◽  
Close Association ◽  
Beating Heart ◽  
Pressure Data ◽  
Heart Model ◽  
Computational Fluid Dynamics Cfd ◽  
Flow Through ◽  
Very High

A computational fluid dynamics (CFD) study has been done comparing pulsatile and non-pulsatile blood flow through the aortic arch and its main branches. The pulsatile flow was to mimic the blood flow due to a beating heart and the non-pulsatile or steady flow was to mimic cardiopulmonary bypass (CPB). The purpose of the study was too narrow in on possible reasons CPB may contribute to the development of atherosclerosis. The main focus of the study was to look at the wall shear stress (WSS) values due to their close association with the development of atherosclerosis. In addition velocity and pressure data were also analyzed. The results of this study showed a stark contrast between the WSS values between the CPB model and the beating heart model. The CPB model did not have any points of oscillating WSS combined with the fact that there were regions of very high and very low constant WSS values in comparison with the beating heart analysis suggests that there may be potential for atherosclerotic development or plaque buildup within the artery. The beating heart model showed a range of WSS values within the aorta that were much lower overall compared with the CPB model.

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