CASE REPORT: CHOROID PLEXUS CARCINOMA IN THE POSTERIOR CRANIAL FOSSA — PATHOLOGICAL ASSESSMENT AND TREATMENT IN A DOG

2014 ◽  
Vol 40 (01) ◽  
pp. 63-68 ◽  
Author(s):  
Pin-Chieh Peng ◽  
Hue-Ying Chiou ◽  
Pin-Hsien Wu ◽  
Ya-Pei Chang ◽  
Peng-Cheng Wang
Keyword(s):  
Choroid Plexus ◽  
Histopathological Examination ◽  
Posterior Cranial Fossa ◽  
Choroid Plexus Carcinoma ◽  
Suboccipital Craniectomy ◽  
Assessment And Treatment ◽  
History Of ◽  
Cranial Fossa ◽  
Magnetic Resonance Imaging Mri

Choroid plexus tumors (PTs) are rare in dogs. Herein, we reported a canine case of choroid plexus carcinoma (CPC) and its clinical treatment. A 10-year-old male Shar Pei presented a two-month history of progressive uncoordinated change in head and gait posture. Magnetic resonance imaging (MRI) showed a lesion in posterior cranial fossa characterized by iso- to hypo-intensity in T1 and iso- to hyper-intensity in T2 with a homogeneous contrast uptake. The case received a one-month course of steroid therapy, and then performed by suboccipital craniectomy. The histopathological examination was described as CPC. The neurological symptoms were immediately and significantly improved after surgery. Follow-up MRI demonstrated that approximately 60% of the tumor was resected. To our knowledge, the clinical outcome of CPC was very poor. In this study, we provided an effective surgical approach, suboccipital craniectomy, for CPC in the posterior cranial fossa to avoid excess brain damage.

Rare intraparenchymal choroid plexus carcinoma resembling atypical teratoid/rhabdoid tumor diagnosed by immunostaining for INI1 protein

2009 ◽  
Vol 4 (4) ◽  
pp. 368-371 ◽  
Author(s):  
E. Andrew Stevens ◽  
Constance A. Stanton ◽  
Kyle Nichols ◽  
Thomas L. Ellis
Keyword(s):  
Choroid Plexus ◽  
Rhabdoid Tumor ◽  
Choroid Plexus Carcinoma ◽  
Nuclear Staining ◽  
Atypical Teratoid Rhabdoid Tumor ◽  
Imaging Studies ◽  
Atypical Teratoid ◽  
History Of ◽  
The Right

The authors present the case of a rare extraventricular, intraparenchymal choroid plexus carcinoma (CPC). This 6-year-old girl presented to the emergency department with a 1-week history of headaches, nausea, and vomiting. Imaging studies revealed an intraaxial cystic and solid mass located in the right frontal lobe with central nodular enhancement and minimally enhancing cyst walls. Gross-total resection was accomplished via craniotomy without complications. The initial pathological diagnosis was atypical teratoid/rhabdoid tumor (AT/RT); however, immunostaining for INI1 protein (using the BAF47/SNF5 antibody) showed retention of nuclear staining in the tumor cells, resulting in a change in the diagnosis to CPC. There was no evidence of recurrence at the last follow-up 2.5 years after treatment, which supports the diagnosis of CPC over AT/RT. This case emphasizes the importance of immunostaining for INI1 protein for distinguishing CPC from AT/RT in cases with atypical or indeterminate features.

scholarly journals Extraventricular Choroid Plexus Carcinoma with Spinal Metastasis: A Case Report

2021 ◽  
Vol 9 (C) ◽  
pp. 93-98
Author(s):  
Rachmat Andi Hartanto ◽  
Daniel Agriva Tamba ◽  
Nurhuda Hendra Setyawan ◽  
Ericko Ekaputra ◽  
Rusdy Ghazali Malueka ◽  
...  
Keyword(s):  
Case Report ◽  
Choroid Plexus ◽  
Frontal Lobe ◽  
Histopathological Examination ◽  
Spinal Metastasis ◽  
Choroid Plexus Carcinoma ◽  
Left Frontal Lobe ◽  
Leptomeningeal Seeding ◽  
Spinal Mri ◽  
Magnetic Resonance Imaging Mri

We report a case of extraventricular choroid plexus carcinoma (CPC) accompanied by spinal metastasis in a pediatric patient. A 15-year-old female patient presented with chronic progressive headache and blurry vision. Magnetic resonance imaging (MRI) revealed an intra-axial mass in the left frontal lobe. A gross total resection was performed, and the histopathological examination revealed the diagnosis of CPC, confirmed with immunohistochemical (IHC) analysis of GFAP, S100, EM, P53 and Ki67. Eleven months later, MRI result identified another mass in the left frontal lobe. Spinal MRI showed drop metastasis to the spine, accompanied by leptomeningeal seeding. This case demonstrated the importance of IHC and spinal MRI in the management of CPC. This case report may provide more insight into extraventricular CPC cases, which is important for the adequate management of patients with CPC in the future.

scholarly journals Schistosomal Cervical Myelopathy

2018 ◽  
Vol 37 (02) ◽  
pp. 151-153
Author(s):  
Ronald Farias ◽  
Kléver Oliveira ◽  
George Mendes ◽  
Ussânio Meira
Keyword(s):  
Spinal Cord ◽  
Inflammatory Diseases ◽  
Histopathological Examination ◽  
Cervical Spinal Cord ◽  
Cervical Cord ◽  
Illustrative Case ◽  
Mild Reduction ◽  
History Of ◽  
Magnetic Resonance Imaging Mri

AbstractSchistosomiasis is an infectious disease caused by trematode platyhelminths of the genus Schistosoma. The involvement of the cervical spinal cord is rare, with few cases reported in the literature. The management of such patients is particularly challenging, since clinical and radiological findings may be confounded with other inflammatory diseases and/ or spinal cord tumors. We describe a 20-year old male with a history of swimming outdoors. He first presented pain in the back of the neck extending to shoulders and upper limbs paresis associated with four limbs hyperreflexia. The magnetic resonance imaging (MRI) showed a hypointense T1-weighted lesion in the cervical spinal cord, which was hyperintense on T2 images. The serologic testing was negative for schistosomiasis. A cervical cord biopsy at the C5-C6 level showed Schistosoma eggs in the histopathological examination. The treatment was performed using a single dose of praziquantel 50 mg/kg, with prednisone 40 mg/day for 3 weeks. On the follow-up, 1 year later, the patient presented mild reduction of the vibratory sensitivity in the distal third of both legs. Our illustrative case strengthens that, in endemic regions, Schistosoma mansoni infestation should be included in the differential diagnosis of intramedullary expansive lesions.

Abdominopelvic Pain in Patient with Uterus Didelphys and Unilateral Obstructed Hemivagina and Ipsilateral Renal Agenesis (OHVIRA Syndrome)

2021 ◽  
Author(s):  
Zahra Tavoli ◽  
Ali Montazeri
Keyword(s):  
Renal Agenesis ◽  
Primary Diagnosis ◽  
Case Presentation ◽  
Uterus Didelphys ◽  
Future Fertility ◽  
History Of ◽  
Ohvira Syndrome ◽  
Obstructed Hemivagina ◽  
Magnetic Resonance Imaging Mri

Introduction: Uterus didelphys with obstructed hemivagina associated with ipsilateral renal agenesis (OHVIRA syndrome) is a rare female urogenital malformation and delay in its diagnosis could lead to several complications. Case presentation: A 21-year-old virgin woman was admitted to the emergency department (ED) with severe abdominal pain, without fever and vaginal discharge. She reported a history of cyclic abdominopelvic pain and dysmenorrhea for 5 years. The primary diagnosis (OHVIRA syndrome) was made using ultrasonography, spiral computed tomography (CT) and magnetic resonance imaging (MRI). In addition, laparoscopy was performed to confirm diagnosis and drain hematosalpinx. Then, hysteroscopy was carried out for septum resection and catheter insertion. At one-month follow-up the ultrasonography showed normal left hemicavity of uterus associated with significant decrease in dysmenorrhea. Conclusion: Being aware of OHVIRA syndrome and clinical suspicion of this rare anomaly are essential for making a timely diagnosis, preventing complications, relieving symptoms, and preserving future fertility.

scholarly journals Reversible splenial lesion syndrome due to oxcarbazepine withdrawal: case report and literature review

2018 ◽  
Vol 46 (3) ◽  
pp. 1277-1281 ◽  
Author(s):  
Chaoyang Jing ◽  
Lichao Sun ◽  
Zhuo Wang ◽  
Chaojia Chu ◽  
Weihong Lin
Keyword(s):  
Case Report ◽  
Corpus Callosum ◽  
Epileptic Seizures ◽  
Resonance Imaging ◽  
Splenial Lesion ◽  
History Of ◽  
Reversible Lesion ◽  
Magnetic Resonance Imaging Mri ◽  
Reversible Splenial Lesion Syndrome

Background Reversible splenial lesion syndrome is a distinct entity radiologically characterized by a reversible lesion in the splenium of the corpus callosum. According to previous reports, this condition may be associated with antiepileptic drug use or withdrawal. We herein report a case of reversible splenial lesion syndrome associated with oxcarbazepine withdrawal. Case Report A 39-year-old man presented with an 8-year history of epileptic seizures. During the previous 3 years, he had taken oxcarbazepine irregularly. One week prior to admission, he withdrew the oxcarbazepine on his own, and the epilepsy became aggravated. Magnetic resonance imaging (MRI) revealed an isolated lesion in the splenium of the corpus callosum with slight hypointensity on T1-weighted imaging and slight hyperintensity on T2-weighted imaging. Regular oxcarbazepine was prescribed. Over a 5-month follow-up period, repeat MRI showed that the abnormal signals in the splenium of the corpus callosum had completely disappeared. Conclusion Reversible splenial lesion syndrome is a rare clinicoradiological disorder that can resolve spontaneously with a favorable outcome. Clinicians should be aware of this condition and that oxcarbazepine withdrawal is a possible etiological factor.

scholarly journals Intracranial subdural osteoma

2020 ◽  
Vol 18 ◽  
pp. 205873922092685
Author(s):  
Yunna Yang ◽  
Zheng Gu ◽  
Yinglun Song
Keyword(s):  
Dura Mater ◽  
Histopathological Examination ◽  
Surgical Excision ◽  
Benign Neoplasms ◽  
Resonance Imaging ◽  
Inner Surface ◽  
History Of ◽  
Magnetic Resonance Imaging Mri ◽  
T1 Hyperintensity ◽  
The Right

Subdural osteomas are extremely rare benign neoplasms. Here, we report the case of a 35-year-old female patient with a right frontal and parietal subdural osteoma. The patient presented with a 2-year history of intermittent headache and fatigue. Computerized tomography (CT) scan showed a high-density lesion attached to the inner surface of the right frontal and parietal skull. Magnetic resonance imaging (MRI) demonstrated T1 hyperintensity and T2 hypointensity of the lesion. Intraoperatively, the hard mass was located in subdural space and attached to the dura mater. Histopathological examination revealed lamellated bony trabeculae lined by osteoblasts and the intertrabecular marrow spaces occupied by adipose tissue. The patient underwent neurosurgical resection and recovered without complication. Surgical excision is recommended to extract the symptomatic lesions with overlying dura mater.

scholarly journals Open-Ring Enhancement in Pseudotumoral Multiple Sclerosis: Important Radiological Aspect

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Frederico Carvalho de Medeiros ◽  
Lucas Alverne Freitas de Albuquerque ◽  
Jose Eymard Homem Pittella ◽  
Renata Brant de Souza ◽  
Antonio Pereira Gomes Neto ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Stereotactic Biopsy ◽  
Demyelinating Disease ◽  
Histopathological Examination ◽  
Previous History ◽  
Open Ring ◽  
Cranial Mri ◽  
History Of ◽  
Radiological Aspect ◽  
Magnetic Resonance Imaging Mri

Introduction. Observation of open-ring enhancement in magnetic resonance imaging (MRI) is considered a specificity marker for diagnosing pseudotumoral multiple sclerosis (MS). This finding is of great value in the differential diagnosis of tumefactive lesions.Case Report. We describe a 55-year-old white woman, with previous history of ovarian cancer and recent history of fatigue and bilateral retroorbital pain. Important bilateral visual impairment evolved over one month. Physical examination detected the presence of right homonymous hemianopia. Cranial MRI showed an expanding lesion with open-ring enhancement. Given the range of diagnostic possibilities, a stereotactic biopsy was performed, and histopathological examination was consistent with an active demyelinating disease. The patient was treated with 1 g of methylprednisolone and symptoms improved following a significant reduction in the lesion.Conclusions. We highlight the MRI results suggestive of pseudotumoral MS, especially open-ring enhancement, which is an important radiologic aspect to diagnosis and can assist in avoiding unnecessary biopsies.

Giant glioependymal cyst in an infant

2011 ◽  
Vol 7 (2) ◽  
pp. 175-178 ◽  
Author(s):  
Ryoma Morigaki ◽  
Kiyohito Shinno ◽  
Kyong-Hon Pooh ◽  
Yoshinobu Nakagawa
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cystic Mass ◽  
Posterior Cranial Fossa ◽  
Resonance Imaging ◽  
Truncal Ataxia ◽  
Glioependymal Cyst ◽  
Tela Choroidea ◽  
Cranial Fossa

The authors report the case of an infant with a giant glioependymal cyst. Although it has been suggested that these cysts originate from the tela choroidea, their origin remains controversial. This 35-month-old girl with truncal ataxia was referred to the authors' hospital. Magnetic resonance imaging revealed a giant cystic mass extending from the anterior to the posterior cranial fossa. Hydrocephalus was caused by obstruction of the sylvian aqueduct. Endoscopic fenestration of the cyst wall was performed. Histochemical and immunohistochemical staining identified the lesion as a glioependymal cyst. Magnetic resonance imaging performed 8 months later suggested that the cyst originated from the tela choroidea. At 5-year follow-up, there was no tumor recurrence and she had fully recovered. The origin of glioependymal cysts is discussed, and the authors suggest that their origin is the tela choroidea.

Choroid plexus carcinoma presenting as an intraparenchymal mass

2001 ◽  
Vol 95 (6) ◽  
pp. 1040-1044 ◽  
Author(s):  
Alexis Byrne Carter ◽  
Donald L. Price ◽  
Keith A. Tucci ◽  
Gregory K. Lewis ◽  
Jeffrey Mewborne ◽  
...  
Keyword(s):  
Choroid Plexus ◽  
Skull Fracture ◽  
Ct Scanning ◽  
Cystic Mass ◽  
Choroid Plexus Carcinoma ◽  
Left Frontal Lobe ◽  
Content Type ◽  
Resected Tissue ◽  
History Of ◽  
The Brain

✓ A 6-year-old girl with a history of a nondisplaced skull fracture diagnosed with computerized tomography (CT) scanning 3 years previously presented with a 6-week history of headaches and decreased use of her right side. On admission CT scans, a large cystic mass was identified in the left frontal lobe region of the brain. A connection between the mass and the ventricular system was not seen on radiological examination or during surgery. Gross-total resection of the mass was achieved. The histological and immunohistochemical findings in the resected tissue confirmed a diagnosis of choroid plexus carcinoma (ChPC). This is the first reported case of a ChPC arising in an extraventricular location not associated with the choroid plexus.

scholarly journals Transient internuclear ophthalmoparesis associated with mutism following midline cerebellar tumour surgery in an 8-year boy

2015 ◽  
Vol 29 (3) ◽  
pp. 323-328
Author(s):  
Guru Dutta Satyarthee ◽  
A.K. Mahapatra
Keyword(s):  
Clinical Features ◽  
Postoperative Period ◽  
Surgical Excision ◽  
Posterior Cranial Fossa ◽  
Mass Lesion ◽  
Pertinent Literature ◽  
Eyelid Closure ◽  
Cerebellar Tumour ◽  
Suboccipital Craniectomy ◽  
Cranial Fossa

Abstract Mutism and neurobehaviour symptoms are well known features, which may occur following surgical excision of mass lesion of various histopathologies in the posterior cranial fossa, during the postoperative period. Mutism may be rarely associated with ataxia of eyelid closure and paresis of external ocular muscles. However, internuclear ophthalmoparesis is not reported in association with mutism following posterior cranial fossa surgery. We report an 8-year–boy, who developed internuclear ophthalmoparesis following suboccipital craniectomy for decompression of vermian medulloblastoma. The clinical features, aetiopathogenesis, management of transient internuclear ophthalmoparesis associated with mutism and pertinent literature is reviewed in short.

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