Vaccination of a multi-group model of zoonotic diseases with direct and indirect transmission

2019 ◽  
Vol 12 (06) ◽  
pp. 1950068
Author(s):  
Wei Lv ◽  
Xue-Ying Liu ◽  
Xin-Jian Xu ◽  
Jie Lou
Keyword(s):  
Function Method ◽  
Reproduction Number ◽  
Vaccination Strategy ◽  
Incidence Rates ◽  
Zoonotic Diseases ◽  
Group Model ◽  
Indirect Transmission ◽  
Lyapunov Function Method ◽  
Theoretical Predictions ◽  
Infectious Pathogen

Vaccination plays an important role in preventing or reducing the spread of zoonotic diseases. In this paper, we develop a susceptible-vaccinated-exposed-infectious-pathogen multi-group epidemic model of zoonotic diseases incorporating nonlinear direct and indirect incidence rates, nonlinear pathogen shedding rates, and common environmental contamination. Under certain assumptions, we first obtained the basic reproduction number of the model. Then, we utilized the comparison principle and global Lyapunov function method to prove global stability of dynamical equilibria. Finally, we analyzed optimal vaccination strategy. All the theoretical predictions were verified by numerical simulations.

A multigroup model for cholera dynamics and control

2015 ◽  
Vol 09 (01) ◽  
pp. 1650001 ◽  
Author(s):  
Drew Posny ◽  
Chairat Modnak ◽  
Jin Wang
Keyword(s):  
Reproduction Number ◽  
Vaccination Strategy ◽  
Sharp Threshold ◽  
Indirect Transmission ◽  
Dynamics And Control ◽  
Simulation Results ◽  
Transmission Pathways ◽  
And Control ◽  
Control Study ◽  
The Basic Reproduction Number

We propose a general multigroup model for cholera dynamics that involves both direct and indirect transmission pathways and that incorporates spatial heterogeneity. Under biologically feasible conditions, we show that the basic reproduction number R0 remains a sharp threshold for cholera dynamics in multigroup settings. We verify the analysis by numerical simulation results. We also perform an optimal control study to explore optimal vaccination strategy for cholera outbreaks.

scholarly journals Impact of early detection and vaccination strategy in COVID-19 eradication program in Jakarta, Indonesia

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Dipo Aldila ◽  
Brenda M. Samiadji ◽  
Gracia M. Simorangkir ◽  
Sarbaz H. A. Khosnaw ◽  
Muhammad Shahzad
Keyword(s):  
Mathematical Model ◽  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Vaccination Strategy ◽  
Vaccination Rate ◽  
Rapid Testing ◽  
Social Distancing ◽  
Rapid Spread ◽  
Vaccine Potential ◽  
The Basic Reproduction Number

Abstract Objective Several essential factors have played a crucial role in the spreading mechanism of COVID-19 (Coronavirus disease 2019) in the human population. These factors include undetected cases, asymptomatic cases, and several non-pharmaceutical interventions. Because of the rapid spread of COVID-19 worldwide, understanding the significance of these factors is crucial in determining whether COVID-19 will be eradicated or persist in the population. Hence, in this study, we establish a new mathematical model to predict the spread of COVID-19 considering mentioned factors. Results Infection detection and vaccination have the potential to eradicate COVID-19 from Jakarta. From the sensitivity analysis, we find that rapid testing is crucial in reducing the basic reproduction number when COVID-19 is endemic in the population rather than contact trace. Furthermore, our results indicate that a vaccination strategy has the potential to relax social distancing rules, while maintaining the basic reproduction number at the minimum possible, and also eradicate COVID-19 from the population with a higher vaccination rate. In conclusion, our model proposed a mathematical model that can be used by Jakarta’s government to relax social distancing policy by relying on future COVID-19 vaccine potential.

Fast Finite-Time Consensus Tracking of First-Order Multi-Agent Systems with a Virtual Leader

2014 ◽  
Vol 596 ◽  
pp. 552-559 ◽  
Author(s):  
Qiu Yun Xiao ◽  
Zhi Hai Wu ◽  
Li Peng
Keyword(s):  
Graph Theory ◽  
Finite Time ◽  
Function Method ◽  
Multi Agent Systems ◽  
Agent Systems ◽  
First Order ◽  
Consensus Tracking ◽  
Lyapunov Function Method ◽  
Multi Agent ◽  
Virtual Leader

This paper proposes a novel finite-time consensus tracking protocol for guaranteeing first-order multi-agent systems with a virtual leader to achieve the fast finite-time consensus tracking. The Lyapunov function method, algebra graph theory, homogeneity with dilation and some other techniques are employed to prove that first-order multi-agent systems with a virtual leader applying the proposed protocol can reach the finite-time consensus tracking. Furthermore, theoretical analysis and numerical simulations show that compared with the traditional finite-time consensus tracking protocols, the proposed protocol can accelerate the convergence speed of achieving the finite-time consensus tracking.

scholarly journals Pinning Synchronization of Switched Complex Dynamical Networks

2015 ◽  
Vol 2015 ◽  
pp. 1-8
Author(s):  
Liming Du ◽  
Feng Qiao ◽  
Fengying Wang
Keyword(s):  
Lyapunov Function ◽  
Complex Networks ◽  
Function Method ◽  
Complex Dynamical Networks ◽  
Switching Topology ◽  
Dynamical Networks ◽  
Switching Law ◽  
Arbitrary Switching ◽  
Lyapunov Function Method ◽  
Networks With Switching Topology

Network topology and node dynamics play a key role in forming synchronization of complex networks. Unfortunately there is no effective synchronization criterion for pinning synchronization of complex dynamical networks with switching topology. In this paper, pinning synchronization of complex dynamical networks with switching topology is studied. Two basic problems are considered: one is pinning synchronization of switched complex networks under arbitrary switching; the other is pinning synchronization of switched complex networks by design of switching when synchronization cannot achieved by using any individual connection topology alone. For the two problems, common Lyapunov function method and single Lyapunov function method are used respectively, some global synchronization criteria are proposed and the designed switching law is given. Finally, simulation results verify the validity of the results.

CHAOS SYNCHRONIZATION VIA UNIDIRECTIONAL COUPLING AND ITS APPLICATION TO SECURE COMMUNICATION

2009 ◽  
Vol 23 (32) ◽  
pp. 5949-5964 ◽  
Author(s):  
XINGYUAN WANG ◽  
MINGJUN WANG
Keyword(s):  
Secure Communication ◽  
Chaos Synchronization ◽  
Function Method ◽  
The Self ◽  
Largest Lyapunov Exponent ◽  
Global Synchronization ◽  
Unidirectional Coupling ◽  
Response System ◽  
Lyapunov Function Method ◽  
Simulation Results

This paper studies chaos synchronization via unidirectional coupling. The self-synchronization of Lorenz systems, modified coupled dynamos systems and hyperchaotic Chen systems is studied by three methods: the Lyapunov function method, the global synchronization method and the numerical calculation of the largest Lyapunov exponent method. In regard to application to communication, we show that via transmitting single signal the synchronization of the drive system and the response system can be achieved. An example of applying self-synchronization of hyperchaotic Chen systems to chaotic masking secure communication is presented in this paper. Simulation results show the effectiveness of the method.

scholarly journals Independent of delay stabilization using implicit Lyapunov function method

Automatica ◽  
2019 ◽  
Vol 101 ◽  
pp. 103-110
Author(s):  
Konstantin Zimenko ◽  
Denis Efimov ◽  
Andrey Polyakov ◽  
Artem Kremlev
Keyword(s):  
Lyapunov Function ◽  
Function Method ◽  
Lyapunov Function Method

scholarly journals Universal varicella vaccination in the Sicilian paediatric population: rapid uptake of the vaccination programme and morbidity trends over five years

2009 ◽  
Vol 14 (35) ◽  
Author(s):  
G Giammanco ◽  
S Ciriminna ◽  
I Barberi ◽  
L Titone ◽  
M Lo Giudice ◽  
...  
Keyword(s):  
Vaccination Programme ◽  
Vaccine Coverage ◽  
Varicella Vaccine ◽  
Age Groups ◽  
Vaccination Strategy ◽  
Paediatric Population ◽  
Incidence Rates ◽  
Universal Vaccination ◽  
Varicella Vaccination ◽  
Local Health

Following the licensure of the Oka/Merck varicella vaccine in Italy in January 2003, the Sicilian health authorities launched a universal vaccination programme in all nine Local Health Units. A two-cohort vaccination strategy was adopted to minimise the shift of the mean age of varicella occurrence to older age groups, with the goal of vaccinating with one dose at least 80% of children in their second year of life and 50% of susceptible adolescents in their 12th year of life. Two studies were implemented in parallel to closely monitor vaccination coverage as well as varicella incidence. Overall, the programme achieved its target, with 87.5% vaccine coverage for the birth cohort 2005 and 90.2% for adolescents born in 1995 and 1996. Varicella surveillance data obtained from a total of 28,188 children (0-14 years-old) monitored by family paediatricians showed a decline in incidence rates from 95.7 (95% confidence interval (CI): 72.2-126.8) for 1,000 person-years (PY) in 2004 to 9.0 (95% CI: 6.4-12.6) for 1,000 PY in 2007. In Europe, the only similar experience is the routine childhood varicella vaccination programme in Germany that started in 2004 with a single dose at the age of 11-14 months. The two-cohort universal vaccination programme implemented in Sicily, as well as the network for the surveillance study, can offer a model to other European countries that are considering introducing universal childhood varicella vaccination.

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