scholarly journals Exploring trade-offs between target coverage, healthy tissue sparing, and the placement of catheters in HDR brachytherapy for prostate cancer using a novel multi-objective model-based mixed-integer evolutionary algorithm

Author(s):  
Krzysztof L. Sadowski ◽  
Marjolein C. van der Meer ◽  
Ngoc Hoang Luong ◽  
Tanja Alderliesten ◽  
Dirk Thierens ◽  
...  
Author(s):  
Ling-Lang Tang ◽  
Yei-Chun Kuo ◽  
E. Stanley Lee

A multi-objective model of global distribution for the Taiwan notebook computer industry is proposed. The proposed two-stage approach involves a mixed integer linear programming model and the fuzzy analytic hierarchy process (AHP) approach. The analytic method provides quantitative assessment of the relationships between manufacturers and customer service. To show the effectiveness of the proposed approach, a Taiwan notebook computer model is solved. The results of this multi-objective model show some dynamic characteristics among various performance criteria of the outbound logistics.


Author(s):  
Ta-Yin Hu ◽  
Guan-Chun Zheng ◽  
Tsai-Yun Liao

Mobility on demand (MOD) provides improved mobility options to all travelers with the use of on-demand information and real-time data. Several alternatives, such as Demand Responsive Transit Systems (DRTS) services, have been introduced around the world. Early DRTS provide on-demand service for areas of low-density population. Nowadays, DRTS are mostly used to provide door-to-door services, and this specific type of DRTS is called Dial-a-Ride Problems (DARP). In this study, a multi-objective model with three objectives, including travel cost, service quality, and eco-efficiency, is formulated. Travel cost is estimated through vehicle travel time, service quality is measured as customer waiting time, and eco-efficiency is measured through consumed fuel. A speed-level variable is introduced in the DARP model to describe travel time, waiting, and consumed fuel simultaneously. For each objective, a single objective model is constructed and implemented. Then, the weighting method with normalization (WMN) is applied for the multi-objective model to solve three objectives. The proposed model is solved through the Gurobi optimizer. Numerical experiments are conducted based on real geometric data in Kaohsiung City. The results show that the proposed model not only provides compromise solutions, but also improves the total performance in meeting three objectives. Pareto front is analyzed with many different combinations of weights to provide more information about the trade-offs between the three objectives. The results can be applied in practice to design vehicle routes for operators and to design DARP evaluation criteria for official agencies.


2003 ◽  
Vol 18 ◽  
pp. 183-215 ◽  
Author(s):  
K. C. Tan ◽  
E. F. Khor ◽  
T. H. Lee ◽  
R. Sathikannan

This paper presents an evolutionary algorithm with a new goal-sequence domination scheme for better decision support in multi-objective optimization. The approach allows the inclusion of advanced hard/soft priority and constraint information on each objective component, and is capable of incorporating multiple specifications with overlapping or non-overlapping objective functions via logical 'OR' and 'AND' connectives to drive the search towards multiple regions of trade-off. In addition, we propose a dynamic sharing scheme that is simple and adaptively estimated according to the on-line population distribution without needing any a priori parameter setting. Each feature in the proposed algorithm is examined to show its respective contribution, and the performance of the algorithm is compared with other evolutionary optimization methods. It is shown that the proposed algorithm has performed well in the diversity of evolutionary search and uniform distribution of non-dominated individuals along the final trade-offs, without significant computational effort. The algorithm is also applied to the design optimization of a practical servo control system for hard disk drives with a single voice-coil-motor actuator. Results of the evolutionary designed servo control system show a superior closed-loop performance compared to classical PID or RPT approaches.


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