Why Do Thiazide Diuretics Lower Blood Pressure in Essential Hypertension?

1967 ◽  
Vol 7 (1) ◽  
pp. 399-408 ◽  
Author(s):  
L Tobian
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Thiazide Diuretics ◽  
Lower Blood Pressure ◽  
Lower Blood

Essential hypertension—definition, epidemiology, and pathophysiology

2010 ◽  
pp. 3023-3039
Author(s):  
Bryan Williams
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Cardiovascular Risk ◽  
High Blood Pressure ◽  
Clinical Benefit ◽  
Lower Blood Pressure ◽  
Significant Clinical Benefit ◽  
Lower Blood ◽  
Absolute Cardiovascular Risk

‘Essential hypertension’ is high blood pressure for which there is no clearly defined aetiology. From a practical perspective, it is best defined as that level of blood pressure at which treatment to lower blood pressure results in significant clinical benefit—a level which will vary from patient to patient depending on their absolute cardiovascular risk....

Plasma Noradrenaline Concentration and Blood Pressure in Essential Hypertension, Phaeochromocytoma and Depression

1974 ◽  
Vol 48 (s2) ◽  
pp. 239s-242s ◽  
Author(s):  
W. J. Louis ◽  
A. E. Doyle ◽  
S. N. Anavekar
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Endogenous Depression ◽  
Plasma Noradrenaline ◽  
Lower Blood Pressure ◽  
Normal Range ◽  
Plasma Noradrenaline Concentration ◽  
Noradrenaline Concentration ◽  
Lower Blood ◽  
Blood Pressures

1. Mean plasma noradrenaline concentration was elevated in forty-four patients with established essential hypertension. Eighteen of these hypertensive patients had resting plasma noradrenaline concentrations in the normal range. 2. Patients with endogenous depression had higher mean plasma noradrenaline concentrations but significantly lower blood pressure than patients with essential hypertension. 3. Patients with phaeochromocytoma had plasma noradrenaline concentrations twenty-eight times greater than those found in essential hypertension, but blood pressures were less than 20% higher. 4. It is concluded that excess of sympathetic drive only partly explains the level of the blood pressure in essential hypertension.

Does Increasing Potassium Intake Lower Blood Pressure in Essential Hypertension?

1984 ◽  
Vol 6 ◽  
pp. S244 ◽  
Author(s):  
Graham A. MacGregor ◽  
Stephen J. Smith ◽  
Nirmala D. Markandu ◽  
Giuseppe A. Sagnella
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Lower Blood Pressure ◽  
Potassium Intake ◽  
Lower Blood

Essential hypertension: Definition, epidemiology, and pathophysiology

2020 ◽  
pp. 3735-3753
Author(s):  
Bryan Williams ◽  
John D. Firth
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Cardiovascular Risk ◽  
Ambulatory Blood Pressure ◽  
Home Blood Pressure ◽  
Lower Blood Pressure ◽  
A Value ◽  
Diagnostic Thresholds ◽  
Lower Blood ◽  
Absolute Cardiovascular Risk

‘Essential hypertension’ is high blood pressure for which there is no clearly defined aetiology. From a practical perspective, it is best defined as that level of blood pressure at which treatment to lower blood pressure results in significant clinical benefit—a level which will vary from patient to patient depending on their absolute cardiovascular risk. Historically, most guidelines define ‘hypertension’ as an office blood pressure greater than or equal to 140/90 mm Hg, but some recent recommendations prefer home or ambulatory blood pressure (blood pressure) averages. When using 24 h ambulatory blood pressure or home blood pressure averages to define hypertension, the diagnostic thresholds are lower than those used with office measurement, with a value of 135/85 mm Hg typically used for both daytime ambulatory blood pressure and home measurements.

scholarly journals The Mechanism of Acupuncture in Treating Essential Hypertension: A Narrative Review

2019 ◽  
Vol 2019 ◽  
pp. 1-10 ◽  
Author(s):  
Juan Li ◽  
Mingsheng Sun ◽  
Jing Ye ◽  
Yuxi Li ◽  
Rongjiang Jin ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Essential Hypertension ◽  
Current Knowledge ◽  
Influence Factors ◽  
Lower Blood Pressure ◽  
Multiple Systems ◽  
Lower Blood ◽  
High Incidence ◽  
Treatment Of Hypertension

Essential hypertension has a high incidence worldwide, and patients with essential hypertension endure a lifetime of medication, leading to a heavy economic burden on the patient’s family and causing serious impacts on the patient’s quality of life. Much evidence has demonstrated that acupuncture as an adjunctive therapy can lower blood pressure in patients with hypertension, but the mechanism of its action is unclear. This article reviews the research from 2000 to 2018 regarding the mechanism of acupuncture for hypertension, and we summarize the current knowledge about using acupuncture for hypertension. We found that the mechanism whereby acupuncture lowers blood pressure is related to the regulation of renin-angiotensin-aldosterone system, vascular endothelium, oxidative stress, neuroendocrine system, and so on. Besides, there may be cross-talk between multiple systems and multiple targets. We also investigate the influence factors of acupuncture for hypertension. These results may provide evidence and research ideas for the treatment of hypertension via acupuncture.

scholarly journals Does sodium restriction lower blood pressure?

BMJ ◽  
1986 ◽  
Vol 293 (6541) ◽  
pp. 266-267 ◽  
Author(s):  
M R Lee ◽  
J A Critchley ◽  
R F Jeffrey ◽  
S Freestone ◽  
T M MacDonald
Keyword(s):  
Blood Pressure ◽  
Sodium Restriction ◽  
Lower Blood Pressure ◽  
Lower Blood
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