scholarly journals Radiology Department Preparedness for COVID-19: Radiology Scientific Expert Review Panel

Radiology ◽  
2020 ◽  
Vol 296 (2) ◽  
pp. E106-E112 ◽  
Author(s):  
Mahmud Mossa-Basha ◽  
Carolyn C. Meltzer ◽  
Danny C. Kim ◽  
Michael J. Tuite ◽  
K. Pallav Kolli ◽  
...  
Keyword(s):  
Radiology Department ◽  
Review Panel ◽  
Expert Review ◽  
Expert Review Panel

Determination and Confirmation of Parent and Total Ractopamine in Bovine, Swine, and Turkey Tissues by Liquid Chromatography with Tandem Mass Spectrometry: First Action 2011.23

2012 ◽  
Vol 95 (5) ◽  
pp. 1235-1255 ◽  
Author(s):  
Thomas J Burnett ◽  
John M Rodewald ◽  
Sharon L Brunelle ◽  
Mark Neeley ◽  
Michael Wallace ◽  
...  
Keyword(s):  
Internal Standard ◽  
Veterinary Drug ◽  
Review Panel ◽  
Validation Data ◽  
Expert Review ◽  
Maximum Residue Limits ◽  
Initial Extract ◽  
Expert Review Panel ◽  
Single Laboratory

Abstract A candidate method selected by the AOAC Expert Review Panel (ERP) for Ractopamine for determination and confirmation of parent and total ractopamine by LC/MS/MS was validated in a single laboratory for bovine, swine, and turkey tissues. The candidate method utilizes methanol extraction of the tissues, followed by an optional enzymatic hydrolysis for determination of total (parent plus conjugate) ractopamine. A mixed-mode cation exchange SPE cartridge is used to purify the initial extract before LC/MS/MS. Matrix-matched standards and a ractopamine-d6 internal standard are used for quantification of parent and total ractopamine in unknown samples. Validation data demonstrated that mean intertrial recoveries for ractopamine across all concentrations tested ranged from 79.7 to 102.2% for parent ractopamine and from 79.0 to 100.0% when a hydrolysis step was included. Intertrial repeatability precision ranged from 2.44 to 11.1% for parent ractopamine and 4.97 to 15.0% with hydrolysis. Estimated LOD values were below 0.1 ng/g and LOQ values were validated at 0.25x the maximum residue limits. The data satisfy the requirements of the AOAC Stakeholder Panel for Veterinary Drug Residue Methods for single laboratory validation studies. The method was awarded Official Methods of AnalysisSM First Action 2011.23 by the AOAC ERP on Veterinary Drug Residues.

Determination of Alkaloids in Mitragyna speciosa (Kratom) Raw Materials and Dietary Supplements by HPLC-UV: Single-Laboratory Validation, First Action 2017.14

2018 ◽  
Vol 101 (4) ◽  
pp. 964-965
Author(s):  
Elizabeth M Mudge ◽  
Paula N Brown
Keyword(s):  
Standard Method ◽  
Raw Materials ◽  
Review Panel ◽  
Method Performance ◽  
Performance Requirement ◽  
Expert Review ◽  
Mitragyna Speciosa ◽  
Expert Review Panel ◽  
Single Laboratory

Abstract The AOAC Expert Review Panel (ERP) approved a method for the quantitation of alkaloids in Mitragyna speciosa for consideration as First Action Official MethodSM status. The previously published method summarized a single-laboratory validation of two alkaloids, mitragynine and 7-hydroxymitragynine, in raw materials and finished products. The methods performance was compared with the AOAC Standard Method Performance Requirement 2015.008. With repeatability precision (RSDr) ranging from 0.51 to 0.95% and recoveries from 93.6 to 98.9% in the different product matrices, the ERP adopted the method and provided recommendations for achieving Final Action status.

scholarly journals Vitamin B12 (cyanocobalamin) in Infant Formula Adult/Pediatric Nutritional Formula by Liquid Chromatography with Ultraviolet Detection: Collaborative Study, Final Action 2014.02

2018 ◽  
Vol 101 (4) ◽  
pp. 1112-1118 ◽  
Author(s):  
Ester Campos Giménez ◽  
Frédéric Martin ◽  
F Arella ◽  
J Austad ◽  
S Bandhari ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Vitamin B12 ◽  
Infant Formula ◽  
Collaborative Study ◽  
Review Panel ◽  
Expert Review ◽  
Relative Standard ◽  
Two Samples ◽  
Expert Review Panel ◽  
Repeatability And Reproducibility

Abstract To determine the repeatability and reproducibility figures of the AOAC First Action Official MethodSM 2014.02 (Vitamin B12 in Infant Formula and Adult/Pediatric Formula by Liquid Chromatography with UV Detection), a collaborative study was organized. Twenty-one laboratories located in 13 different countries agreed to participate. The study was divided into two parts. During the first part, the laboratories analyzed two samples in duplicate by using the method described in the protocol. The laboratories that provided results within the expected range were qualified for part two, during which they analyzed 10 samples in blind duplicates. Eighteen laboratories managed to provide results on time for reporting. The results were compared with the Standard Method Performance Requirement (SMPR® 2011.005) established for vitamin B12. The precision results met the requirements stated in the SMPR except for one sample. Repeatability and reproducibility relative standard deviation ranged from 1.1 to 6.5% and from 6.0 to 23.8%, respectively, with only one matrix showing reproducibility values higher than the required 11%. Horwitz ratio values were all well below 2 (0.17–0.78). The AOAC Expert Review Panel (Stakeholder Panel for Infant Formula and Adult Nutritional Expert Review Panel) determined that the data presented met the SMPR and, hence, recommended the method to be granted Final Action status in September 2016.

Determination and Confirmation of Narasin and Monensin in Chicken, Swine, and Bovine Tissues by LC/MS/MS: Final Action 2011.24

2013 ◽  
Vol 96 (4) ◽  
pp. 902-909 ◽  
Author(s):  
Kimberly R Lombardi ◽  
Thomas J Burnett ◽  
Sharon L Brunelle ◽  
W Dennis Ulrey ◽  
Mark R Coleman ◽  
...  
Keyword(s):  
Data Sets ◽  
Acceptance Criteria ◽  
Review Panel ◽  
Expert Review ◽  
Expert Review Panel ◽  
Aoac Official

Abstract A multilaboratory study was conducted to validate the reproducibility of AOAC Official MethodSM 2011.24 for determination of narasin and monensin in chicken, swine, and bovine tissues. This study was intended to satisfy requirements for Final Action status through the AOAC Expert Review Panel process. Ten laboratories participated in the study, analyzing blind duplicates of five incurred residue materials for each analyte. After removal of invalid data sets, the method reproducibility (RSDR 12.8–60.6%, HorRat 0.45–1.47) was within AOAC acceptance criteria. The method was awarded Final Action status by the Official Methods Board on October 4, 2012.

Standardising drug‐induced sleep endoscopy scoring by an expert review panel: Our experience in 81 patients

2021 ◽  
Author(s):  
Eli Van de Perck ◽  
Annelies E. Verbruggen ◽  
Anneclaire V. Vroegop ◽  
Marijke Dieltjens ◽  
Evert Hamans ◽  
...  
Keyword(s):  
Sleep Endoscopy ◽  
Review Panel ◽  
Drug Induced ◽  
Expert Review ◽  
Drug Induced Sleep Endoscopy ◽  
Expert Review Panel

scholarly journals Determination of Curcuminoids in Turmeric Raw Materials and Dietary Supplements by HPLC: Single-Laboratory Validation, First Action 2016.16

2018 ◽  
Vol 101 (1) ◽  
pp. 203-207 ◽  
Author(s):  
Elizabeth M Mudge ◽  
Paula N Brown
Keyword(s):  
Dietary Supplements ◽  
Standard Method ◽  
Raw Materials ◽  
Review Panel ◽  
Method Performance ◽  
Performance Requirement ◽  
Expert Review ◽  
Expert Review Panel ◽  
Single Laboratory

Abstract The AOAC Expert Review Panel (ERP) approved a method for the quantitation of curcuminoids for consideration for First Action Official MethodSM status. The previously published method summarized a single-laboratory validation of three individual curcuminoinds—curcumin, demethoxycurcumin, and bis-demethoxycurcumin—in raw materials and finished products. Method performance was compared with AOAC Standard Method Performance Requirement 2016.003. With repeatability precision ranging from 0.3 to 5.5% and recoveries from 96.6 to 103.3% in the different product matrixes, the ERP adopted the method and provided recommendations for achieving Final Action status.

Determination of Ractopamine in Swine, Bovine, and Turkey Tissues by HPLC with Fluorescence Detection: First Action 2011.22

2012 ◽  
Vol 95 (4) ◽  
pp. 945-958 ◽  
Author(s):  
Thomas J Burnett ◽  
John M Rodewald ◽  
John Moran ◽  
Michael P Turberg ◽  
Sharon L Brunelle ◽  
...  
Keyword(s):  
Bovine Liver ◽  
Veterinary Drug ◽  
Review Panel ◽  
Expert Review ◽  
Veterinary Drug Residue ◽  
Maximum Residue Limits ◽  
Swine Liver ◽  
Expert Review Panel ◽  
Single Laboratory

Abstract A candidate LC method proposed by the Expert Review Panel (ERP) for ractopamine was evaluated in a single-laboratory validation (SLV) study. The matrixes examined included bovine liver, kidney, muscle, and fat; swine liver, kidney, muscle, and fat; and turkey liver and muscle. Solution standards were shown to provide a linear response with an unweighted regression. The method demonstrated acceptable precision (HorRatr values 0.25 to 1.38) and recovery (75.4 to 88.8%) in all fortified matrixes. Method precision was verified with incurred residue tissues (bovine liver, kidney, and muscle; swine liver, kidney, and muscle; and turkey liver and muscle), which yielded RSDr values below 16% for all tissues and below 7% for most tissues. Estimated LOQ values ranged from 1.8 to 20.7 ng/g and support the utility of the method in the range of the maximum residue limits or tolerances for the various tissues. The data satisfy the requirements of the AOAC Stakeholder Panel on Veterinary Drug Residue for SLV studies, and the method was adopted Official Methods of AnalysisSM First Action 2011.22 by the AOAC ERP on Veterinary Drug Residues.

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