mTOR Inhibitor Therapy for Tuberous Sclerosis Complex: Longitudinal Study of Muscle Mass Determined by Abdominal Cross-sectional Imaging with CT and MRI

AbstractAcute gynaecologic disorders are commonly encountered in daily clinical practice of emergency departments (ED) and predominantly occur in reproductive-age women. Since clinical presentation may be nonspecific and physical findings are often inconclusive, imaging is required for a timely and accurate diagnosis. Although ultrasound is the ideal non-invasive first-line technique, nowadays multidetector computed tomography (CT) is extensively used in the ED, particularly when a non-gynaecologic disorder is suspected and differential diagnosis from gastrointestinal and urologic diseases is needed. As a result, CT often provides the first diagnosis of female genital emergencies. If clinical conditions and scanner availability permit, magnetic resonance imaging (MRI) is superior to CT for further characterisation of gynaecologic abnormalities, due to the excellent soft-tissue contrast, intrinsic multiplanar capabilities and lack of ionising radiation.The purpose of this pictorial review is to provide radiologists with a thorough familiarity with gynaecologic emergencies by illustrating their cross-sectional imaging appearances. The present first section will review the CT and MRI findings of corpus luteum and haemorrhagic ovarian cysts, gynaecologic haemoperitoneum (from either ruptured corpus luteum or ectopic pregnancy) and adnexal torsion, with an emphasis on differential diagnosis. Additionally, comprehensive and time-efficient MRI acquisition protocols are provided.

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Cross-sectional Imaging Review of Tuberous Sclerosis

Radiologic Clinics of North America ◽

10.1016/j.rcl.2015.12.003 ◽

2016 ◽

Vol 54 (3) ◽

pp. 423-440 ◽

Cited By ~ 10

Author(s):

Anant Krishnan ◽

Ravi K. Kaza ◽

Dharshan R. Vummidi

Keyword(s):

Tuberous Sclerosis ◽

Cross Sectional ◽

Cross Sectional Imaging ◽

Sectional Imaging

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Retroperitoneal lymphangiectasia: a great clinical masquerade

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20200267 ◽

2020 ◽

Vol 8 (2) ◽

pp. 748

Author(s):

Siddhant Uttam Manwar ◽

Manisha Vishnu Joshi ◽

Devdas Sudhakar Shetty ◽

Upendra Diwakar Bhalerao

Keyword(s):

Clinical Presentation ◽

Imaging Findings ◽

Resonance Imaging ◽

Colour Doppler ◽

Cross Sectional ◽

Cross Sectional Imaging ◽

Anatomical Extent ◽

Sectional Imaging ◽

Magnetic Resonance Imaging Mri ◽

Ct And Mri

Retroperitoneal lymphangiectasia is a very rare lymphatic disorder characterized by abnormal proliferation of lymphatics. We present series of 3 cases of retroperitoneal lymphangiectasia which are diagnosed in our institute with the help of Ultrasonography (USG), Computed Tomography (CT) and Magnetic resonance imaging (MRI) of abdomen and pelvis with unusual clinical presentation. We include clinical features and imaging findings of this disorder with its pathogenesis and diagnosis. Two of the cases were clinically masquerading as hernia and one case was mimicking varicocele. Thorough clinical examination and USG, colour Doppler, CT and MRI are extremely helpful imaging investigation that aid in differentiating these lesions from hernia/ varicocele and the cross sectional imaging like CT and MRI can depict the anatomical extent of the disease.

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Evaluation of genitourinary fistulas in pelvic malignancies with etiopathologic correlation: role of cross sectional imaging in detection and management

British Journal of Radiology ◽

10.1259/bjr.20200049 ◽

2020 ◽

Vol 93 (1111) ◽

pp. 20200049 ◽

Cited By ~ 1

Author(s):

Anitha Mandava ◽

Veeraiah Koppula ◽

Gaurav Sharma ◽

Meghana Kandati ◽

K.V.V.N. Raju ◽

...

Keyword(s):

Imaging Findings ◽

Cross Sectional ◽

Pelvic Malignancies ◽

Contrast Enhanced Ct ◽

Contrast Enhanced ◽

Enhanced Ct ◽

Cross Sectional Imaging ◽

Sectional Imaging ◽

Ct And Mri

Objective: Genitourinary fistulas in pelvic malignancies are abnormal communications occurring due to either locally advanced tumours invading the surrounding organs or post-therapeutic complications of malignancies. In this article we review and describe the role of cross-sectional imaging findings in the management of genitourinary fistulas in pelvic malignancies. Methods: A retrospective study, for the period January 2012 to December 2018, was undertaken in patients with pelvic malignancies having genitourinary fistulas. The cross-sectional (CT and MRI) imaging findings in various types of fistulas were reviewed and correlated with the primary malignancy and the underlying etiopathology. Results: Genitourinary fistulas were observed in 71 patients (6 males, 65 females). 11 types of fistulas were identified in carcinomas of cervix, rectum, ovary, urinary bladder, sigmoid colon, vault, endometrium and prostate. The commonest were rectovaginal and vesicovaginal fistulas. 13 patients had multiple fistulas. The sensitivity, specificity, positive and negative predictive values of CT and MRI are 98%, 100%, 66%, 98% and 95%, 25%, 88% and 50% respectively. Contrast-enhanced CT with oral and rectal contrast is more sensitive and specific than MRI in the evaluation of genitourinary fistulas. Conclusion: Imaging findings significantly influence the management and outcome of genitourinary fistulas in pelvic malignancies. Contrast-enhanced CT is the imaging modality of choice in the evaluation of pelvic fistulas associated with malignancies and MRI is complimentary to it. Advances in knowledge: To our knowledge, this study is the first of its kind wherein the mean duration of occurrence of fistulas in pelvic malignancies is correlated with the underlying etiopathology.

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Cross-sectional imaging of acute gynaecologic disorders: CT and MRI findings with differential diagnosis—part II: uterine emergencies and pelvic inflammatory disease

Insights into Imaging ◽

10.1186/s13244-019-0807-6 ◽

2019 ◽

Vol 10 (1) ◽

Cited By ~ 1

Author(s):

Pietro Valerio Foti ◽

Massimo Tonolini ◽

Valeria Costanzo ◽

Luca Mammino ◽

Stefano Palmucci ◽

...

Keyword(s):

Differential Diagnosis ◽

Pelvic Inflammatory Disease ◽

Inflammatory Disease ◽

Reproductive Age ◽

Mri Findings ◽

Cross Sectional ◽

Pictorial Review ◽

Cross Sectional Imaging ◽

Sectional Imaging ◽

Ct And Mri

AbstractDue to the growing use of cross-sectional imaging in emergency departments, acute gynaecologic disorders are increasingly diagnosed on urgent multidetector computed tomography (CT) studies, often requested under alternative presumptive diagnoses in reproductive-age women. If clinical conditions and state-of-the-art scanner availability permit, magnetic resonance imaging (MRI) is superior to CT due to its more in-depth characterisationof abnormal or inconclusive gynaecological findings, owing to excellent soft-tissue contrast, intrinsic multiplanar capabilities and lack of ionising radiation.This pictorial review aims to provide radiologists with a thorough familiarity with gynaecologic emergencies by illustrating their CT and MRI appearances, in order to provide a timely and correct imaging diagnosis. Specifically, this second instalment reviews with examples and emphasis on differential diagnosis the main non-pregnancy-related uterine emergencies (including endometrial polyps, degenerated leiomyomas and uterine inversion) and the spectrum of pelvic inflammatory disease.

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