Endothelial function and shear stress in hypobaric hypoxia: time course and impact of plasma volume expansion in men
2020 ◽
Vol 319
(5)
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pp. H980-H994
Keyword(s):
Using a normoxic crossover study design, we examined the impact of hypobaric hypoxia (4 days; altitude equivalent, 3,500 m) and hemoconcentration on blood viscosity, shear stress, and endothelial function. Blood viscosity increased during the hypoxic exposure and was accompanied by elevated resting and exercising arterial shear stress. Flow-mediated dilation stimulated by reactive hyperemia and handgrip exercise was preserved throughout the hypoxic exposure. Plasma volume expansion reversed the hypoxia-associated hemoconcentration and selectively increased handgrip exercise flow-mediated dilation.
2020 ◽
Vol 52
(7S)
◽
pp. 191-191
2018 ◽
Vol 315
(6)
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pp. H1532-H1543
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2013 ◽
Vol 305
(10)
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pp. F1491-F1497
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1988 ◽
Vol 64
(1)
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pp. 404-408
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1974 ◽
Vol 227
(2)
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pp. 245-250
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Keyword(s):
Keyword(s):
2007 ◽
Vol 102
(2)
◽
pp. 828-828
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