Localization of magnesium-28 in the myocardium

1959 ◽  
Vol 196 (2) ◽  
pp. 375-376 ◽  
Author(s):  
W. Glaser ◽  
J. L. Brandt
Keyword(s):  
Skeletal Muscle ◽  
Right Ventricular ◽  
Cardiac Muscle ◽  
Interventricular Septum ◽  
Purkinje System ◽  
Specialized Tissue ◽  
Left And Right

The finding of an unusual concentrating ability of cardiac muscle for magnesium-28 compared to skeletal muscle was confirmed. An extension of this observation showed that the interventricular septum had an even greater ability to concentrate magnesium-28 as compared to the left and right ventricular walls. Studies of isolated Purkinje system in two calves made it unlikely that the distribution of this specialized tissue was the explanation for the distribution of magnesium-28 in the different portions of the ventricles.

Localization of radiomagnesium in puppies: radioautographic study of heart and bone

1962 ◽  
Vol 202 (3) ◽  
pp. 584-588 ◽  
Author(s):  
Warren Glaser ◽  
William D. Gibbs
Keyword(s):  
Right Ventricular ◽  
Intravenous Injection ◽  
Interventricular Septum ◽  
Significant Difference ◽  
Left And Right

Densitometer scans were made of radioautographic images of puppies' hearts and bones produced by magnesium 28. The puppies' renal pedicles were ligated prior to intravenous injection of radioactive magnesium. The puppies were killed 15–20 hr after injection. The densitometer scanning of the heart radioautographs showed the highest densities present in the interventricular septum followed by the left and right ventricular walls. These data are in agreement with those reported for radioassay of magnesium 28 in the heart. The radioautographic images of femurs of puppies showed highest densities produced by magnesium 28 present in the epiphyseal line. Assays for magnesium 28 confirmed that the epiphyseal line contained higher concentrations of the radioisotope than did the diaphyses or epiphyses. There was no statistically significant difference between concentrations of radiomagnesium in epiphyses and diaphyses. Binding of magnesium to protein was found to be 16.3% when determined by ultrafiltration through cellophane.

scholarly journals Diastolic and Systolic Longitudinal Myocardial Velocities of Healthy Racing Pigeons (Columba livia f. domestica) Measured by Tissue Doppler Imaging

2021 ◽  
Vol 8 (2) ◽  
pp. 23
Author(s):  
Marko Legler ◽  
Lajos Koy ◽  
Norbert Kummerfeld ◽  
Michael Fehr
Keyword(s):  
Right Ventricular ◽  
Tissue Doppler Imaging ◽  
Interventricular Septum ◽  
Small Animal ◽  
Columba Livia ◽  
Tissue Doppler ◽  
Repeated Measurements ◽  
Doppler Imaging ◽  
Right Ventricular Free Wall ◽  
Left And Right

Tissue Doppler imaging (TDI) is a noninvasive sonographic method of acquiring and quantifying myocardial velocities. This technique is used in human and small animal medicine to diagnose cardiac diseases. Using this technique, we evaluated the longitudinal myocardial peak velocities of the interventricular septum, and the left and right ventricular free walls in the systole and diastole in 40 racing pigeons. The TDI examinations confirmed the movement of the heart base toward the apex in the systole and away from the apex in the diastole. Inhomogeneous distribution of the myocardial velocities with a statistically significant velocity gradient from the basal to the apical myocardial segments was found. The left and right free walls have significantly higher myocardial velocities than the myocardium of the septum. The myocardial velocities during active ventricular filling were significantly higher in the right ventricular free wall than in the left one. The validation of the method resulted in coefficients of variation between 3% and 33% for the systolic and 3% and 75% for the diastolic individual myocardial velocities. Weekly repeated measurements resulted in variation coefficients between 3% and 45% for systolic and diastolic myocardial velocities, respectively.

Left-to-right systolic ventricular interaction in patients undergoing biventricular stimulation for dilated cardiomyopathy

2010 ◽  
Vol 109 (2) ◽  
pp. 418-423 ◽  
Author(s):  
Giuseppe Osculati ◽  
Gabriella Malfatto ◽  
Roberto Chianca ◽  
Giovanni B. Perego
Keyword(s):  
Right Ventricular ◽  
Dilated Cardiomyopathy ◽  
Biventricular Pacing ◽  
Interventricular Septum ◽  
Systolic Pressure ◽  
Left Ventricular ◽  
Data Set ◽  
Ventricular Interaction ◽  
Left And Right ◽  
The Right

Left-to-right systolic ventricular interaction (i.e., the phenomenon by which the left ventricle contributes to most of the flow and to two-thirds of the pressure generated by the right ventricle) originates from transmission of systolic forces between the ventricles through the interventricular septum and from the mechanical effect of the common muscle fibers encircling their free walls. As a consequence, any reduction of left ventricular free wall function translates in lower right ventricular pressure or function. We investigated whether systolic ventricular interaction could be evidenced in nine patients with dilated cardiomyopathy in whom a biventricular pacemaker was implanted. Changes in right and left ventricular pressures were measured with high-fidelity catheters, before and after periods of biventricular pacing from the right atrium with different stimulation intervals to the right and left ventricles, respectively. The steady-state changes of left and right ventricular systolic pressure obtained from any single pacing interval combination were considered. We then calculated, with a two-level mixed regression analysis of the entire data set, the relation between changes in left and right systolic pressures: the presence of a statistically significant slope was assumed as evidence of ventricular interaction. The slope of the regression replaced the crude pressure ratio as an estimate of the gain of the interaction; its value compared with values observed in experimental studies. Moreover, its dependence on septal elastance and on right ventricular volume was similar to that already demonstrated for ventricular interaction gain. In conclusion, the linear relationship we found between systolic pressure changes in the two ventricles of patients with dilated cardiomyopathy during biventricular pacing could be explained in terms of ventricular interaction.

scholarly journals Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart

2006 ◽  
Vol 294 (2) ◽  
pp. 366-375 ◽  
Author(s):  
Diego Franco ◽  
Sigolène M. Meilhac ◽  
Vincent M. Christoffels ◽  
Andreas Kispert ◽  
Margaret Buckingham ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Interventricular Septum ◽  
Mouse Heart ◽  
Left And Right

Left and right ventricular hypertrophy at autopsy of hypertensive individuals

2012 ◽  
Vol 58 (1) ◽  
pp. 41-47 ◽  
Author(s):  
Mirella Pessoa Sant’Anna ◽  
Roberto José Vieira de Mello ◽  
Luciano Tavares Montenegro ◽  
Mônica Modesto Araújo
Keyword(s):  
Right Ventricular ◽  
Ventricular Hypertrophy ◽  
Right Ventricular Hypertrophy ◽  
Left And Right

Biventricular Mural Endocarditis on the Intraventricular Septum

2015 ◽  
Vol 18 (5) ◽  
pp. 184 ◽  
Author(s):  
Makoto Mori ◽  
Soh Hosoba ◽  
Stephanie Yoshimura ◽  
Omar Lattouf
Keyword(s):  
Right Ventricular ◽  
Rare Case ◽  
Postoperative Management ◽  
Intraventricular Septum ◽  
Left And Right ◽  
Endocardial Surface

<p>Mural endocarditis is an inflammation and disruption of the nonvalvular endocardial surface of the cardiac chambers. We present a rare case of mural endocarditis on the intraventricular (IV) septum on both the left and right ventricular side with intact valvular annulus. This case highlights the complexity of the operative and postoperative management in an unprecedented case of biventricular mural endocarditis.</p>

Skeletal and cardiac muscle protein turnover during cold acclimation in young rats

2000 ◽  
Vol 278 (3) ◽  
pp. R705-R711 ◽  
Author(s):  
T. A. McAllister ◽  
J. R. Thompson ◽  
S. E. Samuels
Keyword(s):  
Skeletal Muscle ◽  
Protein Synthesis ◽  
Cardiac Muscle ◽  
Cold Acclimation ◽  
Protein Turnover ◽  
Muscle Protein ◽  
Muscle Protein Turnover ◽  
Protein Mass ◽  
The Absolute

The effect of long-term cold exposure on skeletal and cardiac muscle protein turnover was investigated in young growing animals. Two groups of 36 male 28-day-old rats were maintained at either 5°C (cold) or 25°C (control). Rates of protein synthesis and degradation were measured in vivo on days 5, 10, 15, and 20. Protein mass by day 20 was ∼28% lower in skeletal muscle (gastrocnemius and soleus) and ∼24% higher in heart in cold compared with control rats ( P < 0.05). In skeletal muscle, the fractional rates of protein synthesis ( k syn) and degradation ( k deg) were not significantly different between cold and control rats, although k syn was lower (approximately −26%) in cold rats on day 5; consequent to the lower protein mass, the absolute rates of protein synthesis (approximately −21%; P < 0.05) and degradation (approximately −13%; P < 0.1) were lower in cold compared with control rats. In heart, overall, k syn(approximately +12%; P < 0.1) and k deg(approximately +22%; P < 0.05) were higher in cold compared with control rats; consequently, the absolute rates of synthesis (approximately +44%) and degradation (approximately +54%) were higher in cold compared with control rats ( P < 0.05). Plasma triiodothyronine concentration was higher ( P < 0.05) in cold compared with control rats. These data indicate that long-term cold acclimation in skeletal muscle is associated with the establishment of a new homeostasis in protein turnover with decreased protein mass and normal fractional rates of protein turnover. In heart, unlike skeletal muscle, rates of protein turnover did not appear to immediately return to normal as increased rates of protein turnover were observed beyond day 5. These data also indicate that increased rates of protein turnover in skeletal muscle are unlikely to contribute to increased metabolic heat production during cold acclimation.

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