scholarly journals Applications of Recombinant DNA Technology in Gastrointestinal Medicine and Hepatology: Basic Paradigms of Molecular Cell Biology. Part A: Eukaryotic Gene Structure and DNA Replication

2000 ◽  
Vol 14 (2) ◽  
pp. 99-110
Author(s):  
Gary E Wild ◽  
Patrizia Papalia ◽  
Mark J Ropeleski ◽  
Julio Faria ◽  
Alan BR Thomson
Keyword(s):  
Cell Biology ◽  
Recombinant Dna ◽  
Relevant Information ◽  
Core Knowledge ◽  
Recombinant Dna Technology ◽  
New Information ◽  
Eukaryotic Gene ◽  
Dna Technology ◽  
Medical Subspecialty ◽  
Molecular Pathophysiology

Progress in the basic sciences of cell and molecular biology has provided an exciting dimension that has translated into clinically relevant information in every medical subspecialty. Importantly, the application of recombinant DNA technology has played a major role in unravelling the intricacies related to the molecular pathophysiology of disease. This series of review articles constitutes a framework for the integration of the database of new information into the core knowledge base of concepts related to the pathogenesis of gastrointestinal disorders and liver disease. The goal of this series of three articles is to review the basic principles of eukaryotic gene expression. The first article examines the role of DNA in directing the flow of genetic information in eukaryotic cells.

scholarly journals Biotegnologie — ’n Nuwe benadering in planteteling

1991 ◽  
Vol 10 (1) ◽  
pp. 18-25
Author(s):  
D. I. Ferreira
Keyword(s):  
Tissue Culture ◽  
Molecular Biology ◽  
Plant Breeding ◽  
Cell Biology ◽  
Crop Production ◽  
Recombinant Dna ◽  
Global Approach ◽  
Recombinant Dna Technology ◽  
Half Century ◽  
Dna Technology

Conventional plant breeding has made a significant impact on the increase in crop production during the last half century. Several shortcomings however, opened up the opportunities for the application of biotechnology in plant breeding. The vari­ous approaches in the field of cell biology (tissue culture) and molecular biology (recombinant DNA technology) are dis­cussed and the application thereof is advocated in a global approach to plant breeding.

scholarly journals Biotin Production by Using Recombinant DNA Technology

1992 ◽  
Vol 38 (Special) ◽  
pp. 263-266
Author(s):  
O. IFUKU ◽  
S. HAZE ◽  
J. KISHIMOTO ◽  
M. YANAGI
Keyword(s):  
Recombinant Dna ◽  
Recombinant Dna Technology ◽  
Dna Technology

Introduction to Recombinant DNA

PEDIATRICS ◽  
1984 ◽  
Vol 74 (3) ◽  
pp. 408-411
Author(s):  
Stephen D. Cederbaum
Keyword(s):  
Inborn Errors Of Metabolism ◽  
Recombinant Dna ◽  
Phenylalanine Hydroxylase ◽  
Professional Lives ◽  
Recombinant Dna Technology ◽  
Inborn Errors ◽  
Dna Technology ◽  
Basic Vocabulary ◽  
The Moment ◽  
The Many

Seldom has a scientific or biomedical break-through evoked the awe, controversy, or sheer incredulity that has accompanied the developments in the field of recombinant DNA technology or more popularly, gene cloning and genetic engineering. Now little more than one generation after Avery, et al1 demonstrated that genes were encoded in DNA and Watson and Crick2 interpreted the structure of these molecules, genes are being cut, manipulated, and recombined to produce unprecedented new insights into genetics and molecular biology and the prospect of gene therapy. These developments have not occurred without anxiety to both scientists and laymen. At the moment, neither the most apocalyptic fears nor the most optimistic dreams appear to be imminent, although I believe that the dreams are closer to fulfillment than the fears. Recombinant DNA technology is already having great impact in hematology, oncology, endocrinology, immunology, and infectious disease and will soon play an important role in other medical subspecialities as well. In none, however, will it have quite the same impact as in genetics because DNA is the material that genetics "is all about." The cloning and study of phenylalanine hydroxylase is one of the first instances in which this technology has important implications in the diseases traditionally classified as inborn errors of metabolism. In order to understand and appreciate the presentation by Woo on phenylalanine hydroxylase as well as the many future papers that will play so vital a role in all of our professional lives, it is necessary to acquire the basic vocabulary of the field.

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