scholarly journals Pemphigus Vulgaris Confined to the Gingiva: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Mitsuhiro Ohta ◽  
Seiko Osawa ◽  
Hiroyasu Endo ◽  
Kayo Kuyama ◽  
Hirotsugu Yamamoto ◽  
...  
Keyword(s):  
Case Report ◽  
Lichen Planus ◽  
Oral Mucosa ◽  
Pemphigus Vulgaris ◽  
Oral Lesions ◽  
Skin Involvement ◽  
Mucous Membranes ◽  
History Of ◽  
Blistering Disease ◽  
One Year

Pemphigus Vulgaris (PV) is an autoimmune intraepithelial blistering disease involving the skin and mucous membranes. Oral mucosa is frequently affected in patients with PV, and oral lesions may be the first sign of the disease in majority of patients. In some patients, oral lesions may also be followed by skin involvement. Therefore, timely recognition and therapy of oral lesions is critical as it may prevent skin involvement. Early oral lesions of PV are, however, often regarded as difficult to diagnose, since the initial oral lesions may be relatively nonspecific, manifesting as superficial erosions or ulcerations, and rarely presenting with the formation of intact bullae. Lesions may occur anywhere on the oral mucosa including gingiva; however; desquamtive gingivitis is less common with PV than other mucocutaneous conditions such as pemphigoid or lichen planus. This paper describes the case of a patient presenting with a one-year history of painful gingival, who is finally diagnosed as having PV.

scholarly journals MANIFESTASI DAN PENATALAKSANAAN PEMFIGUS VULGARIS DI RONGGA MULUT

2018 ◽  
Vol 2 (2) ◽  
pp. 117-124
Author(s):  
Indra Gunawan ◽  
Riani Setiadhi
Keyword(s):  
Case Report ◽  
Early Recognition ◽  
Pemphigus Vulgaris ◽  
Oral Lesions ◽  
Oral Manifestations ◽  
Skin Involvement ◽  
Mucous Membranes ◽  
Blistering Disease ◽  
Mouth Wash ◽  
Desmoglein 3

Background : Pemphigus Vulgaris (PV) is an autoimmune intraepithelial blistering disease involving the skin and mucous membranes. Oral lesions could be the first sign of the disease followed by the involvement of skin and other mucosa sites.Objectives : This is oral manifestations of pemphigus vulgaris case report, intended to help clinicians to recognize and treat the oral lesions.Case Reported : Male 27 yo admitted to RSUP Dr.Hasan Sadikin hospital with multiple blisters on the skin and oral mucosa, was diagnosed with Pemphigus Vulgaris.Case Management : Patient was treated with steroid mouth wash and oral paste. After two months of treatment, the patient was fully recovered from oral lesion.Discussion : In PV, autoantibodies are produced against desmosomes spesifically desmoglein 3 which responsible for holding the cells of the epithelium together. The loss of adhesive function due to anti Dsg 3 antibodies result in bulla formation on the oral mucosa.The aetiology for PV is still uncertain. Conclusion :Early recognition and treatment of oral lesions is important as it may prevent skin involvement. Early treatment, patient’s compliance and multi disciplinal teamwork ensure the treatment succes for this disease

scholarly journals Pemphigus Vulgaris in Old Patient

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Bassel Tarakji
Keyword(s):  
Differential Diagnosis ◽  
Autoimmune Disease ◽  
Oral Mucosa ◽  
Oral Prednisolone ◽  
Pemphigus Vulgaris ◽  
The Other ◽  
Oral Lesions ◽  
Oral Medicine ◽  
Mucous Membranes ◽  
Blistering Disease

Pemphigus vulgaris (PV) is a chronic, autoimmune, intraepidermal blistering disease of the skin and mucous membranes. The first clinical manifestation is often the development of intraoral lesions, and later, the lesions involve the other mucous membranes and skin. The etiological factors of this disease still remain unknown, although the presence of autoantibodies is consistent with an autoimmune disease. A 73-year-old man had bullous lesions on gingiva, oral mucosa first, then scalp, trunk, and face. An oral medicine specialist suspects the lesion in differential diagnosis in the first presentation of oral lesions and follows up the patient, and then these bullous lesions presented on the skin. In this article, a patient had received oral prednisolone (80 mg/kg/day) and azathioprine, then tapered oral prednisolone to 40 mg/day, with a reduction of 5 mg/day every three weeks. The patient shows remission of these lesions, and complication of this treatment includes osteoporosis, hyperglycemia, and hypertension.

scholarly journals The Effects of NBF Gingival Gel Application in the Treatment of the Erosive Lichen Planus: Case Report

2016 ◽  
Vol 4 (1) ◽  
pp. 158-163 ◽  
Author(s):  
Mirjana Popovska ◽  
Jasmin Fidovski ◽  
Sonja Mindova ◽  
Katerina Dirjanska ◽  
Stevica Ristoska ◽  
...  
Keyword(s):  
Case Report ◽  
Lichen Planus ◽  
Oral Mucosa ◽  
Clinical Effects ◽  
Oral Lesions ◽  
Short Time Period ◽  
The Third ◽  
Time Period ◽  
Erosive Lichen Planus ◽  
Short Time

The therapy of erosive lichen planus (ELP) has been particular problem in the treatment of oral lesions. This case of ELP in male patient 29 years old was treated with topic application of the NBF gingival gel, three times a day after meal, previously rinsed with Clorhexidine gluconate 0.12%. After 5 days of treatment, initial improvements were recorded, and after two weeks of application of the NBF gingival gel we observed significant improvement. Clinical monitoring after the fifth day showed mild epithelialization of the eroded mucosa, yet still present erythematous base of the lesion. After the second week the erythema area was significantly reduced and the eroded surfaces of the mucosa were minimal, measured less than 0.5 mm. After the third week there were no erosions to detect on the oral mucosa, yet still present vague redness, which completely pulled after the fourth week. Treatment ended after the fifth week when the topical application of the NBF gingival gel was terminated, and therapy was done, and clinically achieved effects remained stable even after the third month of the treatment. Topic application of the NBF gingival gel with ELP patients showed positive clinical effects in relatively short time period.

Pemphigus Vulgaris With Oral Mucosa and Skin Involvement: A Case Report

2015 ◽  
Vol 120 (2) ◽  
pp. e57
Author(s):  
PEDRO EVERTON MARQUES GOES ◽  
ANIBAL HENRIQUE BARBOSA LUNA ◽  
LUDMILA SILVA DE FIGUEIREDO ◽  
EDUARDO DE ALMEIDA SOUTO MONTENEGRO ◽  
KAROLINE GOMES DA SILVEIRA ◽  
...  
Keyword(s):  
Case Report ◽  
Oral Mucosa ◽  
Pemphigus Vulgaris ◽  
Skin Involvement

scholarly journals Pemphigus Vulgaris as Oral Mucosal Ulcer Progressive to Skin Lesion:

2014 ◽  
Vol 3 (2) ◽  
pp. 43-47
Author(s):  
SM Anwar Sadat ◽  
Akhter Imam
Keyword(s):  
Public Health ◽  
Pemphigus Vulgaris ◽  
Health It ◽  
Major Threat ◽  
Floor Of The Mouth ◽  
Autoimmune Blistering Disease ◽  
Life Threatening ◽  
History Of ◽  
Blistering Disease ◽  
One Year

Among all the life threatening diseases, autoimmune diseases are among most notorious and complicated diseases. As these diseases have no specific cause or responsible organism, it is therefore very difficult to distinguish and diagnose and thus stands as a major threat for public health. It is assumed that the reason for these diseases may be from genetic to environmental factors, from stress to idiopathic origin. Pemphigus Vulgaris(PV) is such an autoimmune blistering disease that frequently affects the mucous membrane and skin. Very often it starts from oral cavity and Dentists therefore the first to recognize. This paper describes the case of a patient presenting with a one-year history of painful ulcerated gingiva, tongue, floor of the mouth and even on GIT who is finally diagnosed as having PV spreading to generalized skin. DOI: http://dx.doi.org/10.3329/updcj.v3i2.17999 Update Dent. Coll. j: 2013; 3 (2): 43-47

Sweet Syndrome and Pemphigus Vulgaris

2012 ◽  
Vol 16 (2) ◽  
pp. 128-130 ◽  
Author(s):  
Ashley O'toole ◽  
Maureen O'malley
Keyword(s):  
Clinical Presentation ◽  
Pemphigus Vulgaris ◽  
Neutrophilic Dermatosis ◽  
Rare Presentation ◽  
Sweet Syndrome ◽  
Autoimmune Blistering Disease ◽  
Mucous Membranes ◽  
Blistering Disease ◽  
Erythematous Plaques ◽  
New Onset

Background: Pemphigus vulgaris is an autoimmune blistering disease of the skin and mucous membranes. Sweet syndrome is an uncommon reactive neutrophilic dermatosis. Objective: This case report describes the rare presentation of a 58-year-old female patient with newly diagnosed pemphigus vulgaris who later presented with erythematous plaques and leukocytosis highly suggestive of Sweet syndrome. Methods: Review of the literature using the PubMed and Medline databases. Results: The clinical presentation of new-onset Sweet syndrome in a patient with pemphigus has been reported in the literature only on one other occasion. Conclusion: The observation of an association between Sweet syndrome and autoimmune diseases, such as pemphigus vulgaris, may ultimately lead to better understanding of the pathophysiology of this disease.

Traumatic ulcers with a hidden cause: A case report

Dental Update ◽  
2021 ◽  
Vol 48 (2) ◽  
pp. 141-143
Author(s):  
Pavneet Chana ◽  
Daniela Ion
Keyword(s):  
Case Report ◽  
Oral Mucosa ◽  
Secondary Care ◽  
Clinical Relevance ◽  
Clinical Presentation ◽  
Common Condition ◽  
Oral Ulceration ◽  
History Of

Oral ulceration is a common condition that can affect the oral mucosa, and patients often present in both primary and secondary care. There are a number of causes of oral ulceration, ranging from trauma to malignancy. The cause of the oral ulceration can be difficult to establish, especially when the history and investigations do not support an obvious cause. We report a case of a 19-year-old male who presented with a 2-month history of worsening oral ulceration. Despite further questioning and investigations, the cause of the oral ulceration remained elusive. CPD/Clinical Relevance: To understand the clinical presentation and causes of oral ulceration.

Therapy of the Intra- and Extra-Oral Lesions of Pemphigus Vulgaris: a Case Report

2018 ◽  
Vol 126 (3) ◽  
pp. e143
Author(s):  
Tayna Soares De Oliveira ◽  
Lucas Lavareze Dos Reis ◽  
Thuany Servare De Lima ◽  
Danielle Resende Camisasca ◽  
Tânia Regina Grão Velloso ◽  
...  
Keyword(s):  
Case Report ◽  
Pemphigus Vulgaris ◽  
Oral Lesions

Pemphigus Vulgaris Arising from Oral Lesions; A Case Report.

1995 ◽  
Vol 88 (1) ◽  
pp. 49-53
Author(s):  
Haruo HIRAKAWA ◽  
Yukiko IINO
Keyword(s):  
Case Report ◽  
Pemphigus Vulgaris ◽  
Oral Lesions

Linear Lichen Planus: Continuum From Skin to Mucosa

2017 ◽  
Vol 22 (2) ◽  
pp. 232-233
Author(s):  
Mikhin George Thomas ◽  
Ambooken Betsy
Keyword(s):  
Lichen Planus ◽  
Oral Mucosa ◽  
Unusual Presentation ◽  
Inflammatory Disorder ◽  
Upper Lip ◽  
Middle Aged ◽  
Linear Distribution ◽  
Chronic Inflammatory Disorder ◽  
Mucous Membranes

Lichen planus (LP) is a chronic inflammatory disorder that most commonly affects middle-aged individuals. LP involves the skin and/or mucous membranes, including oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. Linear LP, a rare distinct variant of LP, is characterised by pruritic eruption of lichenoid and violaceous papules in a linear distribution. We report an unusual presentation of linear LP in a 14-year-old child that extended from the left anterior nares to upper lip and into the oral mucosa up to the upper gum margin.

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