scholarly journals Fluoride Retention following the Professional Topical Application of 2% Neutral Sodium Fluoride Foam

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Wenqun Song ◽  
Shinji Toda ◽  
Eri Komiyama ◽  
Karin Komiyama ◽  
Yuki Arakawa ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Sodium Fluoride ◽  
Topical Application ◽  
Neutral Sodium

The objective of the present research was to determine the appropriate amount of fluoride to use professional topical application and the residual amounts of fluoride in the oral cavity using a 2% neutral sodium fluoride (NaF) foam with a dedicated tray. Using dentition study models, a method for determining the appropriate amount of NaF foam was investigated. In eight adult subjects, the appropriate amount of NaF foam, the concentration of fluoride in the saliva following professional topical application, and the amount of residual fluoride in the oral cavity following professional topical application was examined. The results indicated that the appropriate amount of NaF foam was approximately 0.8 g, the amount of residual fluoride in the oral cavity was approximately 25% of the amount of foam used.

Cariostatic Activity of (1,6-Bis-[2-Ethylhexylbiguanido]-Hexane) in Conventional Rats

1979 ◽  
Vol 58 (4) ◽  
pp. 1405-1412 ◽  
Author(s):  
Stephen N. Curtis ◽  
Claire L. Dooley
Keyword(s):  
Drinking Water ◽  
Oral Cavity ◽  
Streptococcus Mutans ◽  
Sodium Fluoride ◽  
Progressive Increase ◽  
Continuous Administration ◽  
Low Concentrations ◽  
Very High

The antimicrobial and cariostatic activities of the dihydrochloride and dihydrofluoride salts of alexidine (1, 6-bis-[2-ethylhexylbiguanido]hexane) were compared to those of chlorhexidine acetate and sodium fluoride in rats implanted orally with Streptococcus mutans 6715 and fed a cariogenic diet. Experimental caries was significantly reduced by the continuous administration of low concentrations of biguanides via the drinking water, but this was accompanied by increased staining of the molars. Very high biguanide concentrations, applied infrequently, directly to the molars, effectively reduced caries and resulted in less staining. A combination of alexidine dihydrochloride and sodium fluoride offered no advantage over either drug alone. Alexidine salts prevented the progressive increase in implanted S. mutans, whereas chlorhexidine acetate practically eliminated the microorganism from the oral cavity. Sodium fluoride had no effect on the implanted flora. It was concluded that alexidine salts are comparable in cariostatic activity to chlorhexidine. The tooth staining accompanying the use of bisbiguanides can be reduced by adjusting the concentration of the drug and its frequency of application.

scholarly journals EDX-analysis of fluoride precipitation on human enamel

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Konstantin Johannes Scholz ◽  
Marianne Federlin ◽  
Karl-Anton Hiller ◽  
Helga Ebensberger ◽  
Gerlinde Ferstl ◽  
...  
Keyword(s):  
Sodium Fluoride ◽  
Ph Value ◽  
Human Saliva ◽  
Pellicle Formation ◽  
Treatment Groups ◽  
Human Enamel ◽  
Salivary Pellicle ◽  
Semiquantitative Method ◽  
Neutral Sodium

Abstract One mechanism of action for the anticaries effect of topical fluoridation is through precipitation of CaF2. In this in vitro study energy-dispersive x-ray spectroscopy (EDX) is used as a semiquantitative method to detect enamel fluoride-precipitation under the influence of acidic and neutral pH-value and absence or presence of a salivary pellicle. Crowns of 30 human caries-free third molars were quartered into four specimens and the enamel surface ground flat and polished. Two specimens each were stored in human saliva (120 minutes pellicle formation). Teeth were randomly allocated into 6 treatment groups: NaF_a (experimental acidic sodium fluoride; 12500 ppmF−, pH 4.75); NaF_n (experimental neutral sodium fluoride; 12500 ppmF−, pH 7.0); GB_a (acidic gel base; 0 ppmF−, pH 4.75); GB_n (neutral gel base; 0 ppmF−, pH 7.0); AmF-NaF_a (experimental acidic amine/sodium fluoride; 12500 ppmF−, pH 4.75); EG_a (acidic amine/sodium fluoride; Elmex Geleé, CP-GABA GmbH; 12500 ppmF−, pH 4.75). Each gel was applied for 60 seconds to one specimen with and one specimen without pellicle. Two specimens served as controls (no gel, without/with pellicle). Atomic percent (At%) of O, F, Na, Mg, P, Ca was measured by EDX. ∆At% and Ca/P-ratios were calculated. EDX could semi-quantify superficial enamel fluoride-precipitation. Only specimens treated with acidic fluoride gels showed fluoride-precipitation, a salivary pellicle tended to decrease At%F.

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