Spectral Characterization and Antibacterial Activities of Benzyloxybenzaldehydethiosemicarbazone, 3,4-Dihydroxybenzaldehydeisonicotinoylhydrazone and their Transitional Metal Complexes

The synthesis and spectral characterization of benzyloxy-benzaldehydethiosemicarbazone (BBTSC) and the study of antibacterial activity of ligands BBTSC, 3,4-dihydroxybenzaldehydeisoni- cotinoylhydrazone (3,4-DHBINH) and their transition metal complexes was studied. The composition of the metal complexes was also evaluated by using Job’s method, molar-ratio method and Asmus’ method. The antibacterial activities of BBTSC, 3,4-DHBINH and their complexesi.e., Cu(II)-BBTSC, Pd(II)-BBTSC, Cr(VI)- 3,4-DHBINH, Ti(IV)- 3,4-DHBINH and Pd(II)-3,4-DHBINH were studied against two gram positive bacteria and two gram negative bacteria. Antibacterial activities were evaluated by agar cup well method with the help of Luria Bertoni plates.

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Biological Study of Transition Metal Complexes with Adenine Ligand

Proceedings ◽

10.3390/ecsoc-23-06601 ◽

2019 ◽

Vol 41 (1) ◽

pp. 77 ◽

Cited By ~ 1

Author(s):

Hamad M. I. Hasan ◽

Aaza I. Yahiya ◽

Safaa S. Hassan ◽

Mabrouk M. Salama

Keyword(s):

Metal Complexes ◽

Molar Conductance ◽

Molar Ratio ◽

Biological Study ◽

Ratio Method ◽

Spectroscopic Techniques ◽

Stoichiometric Ratio ◽

Metal Contents ◽

Molar Ratio Method

Adenine complexes were prepared with some of the first series transition metals in a stoichiometric ratio of 1: 2 (Mn+: L), where Mn+ = Mn2+, Fe3+, Co2+, Ni2+, Cu2+, Zn2+, and Cd2+ ions. The Complexes were characterized by the physicochemical and spectroscopic techniques as electric conductivity, metal contents, IR, UV–Visible, and molar conductance techniques. The stoichiometric ratios of the synthesized complexes were confirmed by using molar ratio method. The dissociation constant of adenine ligand was determined spectrophotometrically. Solvent effect on the electronic spectra of the adenine ligand was examined using solvents with different polarities. The biological activity of adenine ligand and its metal complexes were tested in vitro against some selected species of fungi and bacteria. The results showed a satisfactory spectrum against the tested organisms.

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Antitumor and Antimicrobial Potential of Manganese(II), Nickel(II) and Copper(II) Complexes of 4-Methoxy Benzohydrazide Derived Schiff Base Ligand

Letters in Applied NanoBioScience ◽

10.33263/lianbs111.32493260 ◽

2021 ◽

Vol 11 (1) ◽

pp. 3249-3260

Keyword(s):

Schiff Base ◽

Metal Complexes ◽

Schiff Base Ligand ◽

Antimicrobial Activities ◽

Molar Ratio ◽

Gram Positive Bacteria ◽

Ft Ir ◽

Dose Dependent

Herein, we describe the synthesis and characterization of a Schiff base ligand (E)-N'-(2-hydroxybenzylidene)-4-methoxybenzohydrazide (HBMB) and its Mn(II), Ni(II), and Cu(II) metal complexes (C1-C3) respectively. The ligand HBMB was synthesized by reacting condensation of salicylaldehyde and 4-methoxy benzohydrazide in a 1:1 molar ratio. The structure of HBMB and its metal complexes (C1-C3) were evaluated by using UV-Vis, FT-IR, 1H-NMR, mass spectroscopy as well as on the basis of elemental analysis, conductivity measurements, and thermogravimetric techniques (TGA). The synthesized molecules' tumoricidal properties were performed against human breast cancer (MCF-7) and colon cancer (HT 29) cell lines. The biological results indicated that the ligand, HBMB, and metal complexes possess dose-dependent selective cytotoxicity against the tested carcinoma cells. The synthesized compounds were further evaluated for their in vitro antimicrobial activities against Gram-positive bacteria (Staphylococcus aureus), Gram-negative bacteria (Escherichia coli), and fungal strains (Aspergillus niger).

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Preparation, Characterization and Antimicrobial Activity Study of Some Transition Metal Complexes of 4-Flourophenyl -4-Nitrobenzylidene

Baghdad Science Journal ◽

10.21123/bsj.7.2.1006-1013 ◽

2010 ◽

Vol 7 (2) ◽

pp. 1006-1013

Author(s):

Baghdad Science Journal

Keyword(s):

Metal Complexes ◽

Metal Ion ◽

Synergetic Effect ◽

Free Ligand ◽

Molar Ratio ◽

Ratio Method ◽

Flame Atomic Absorption ◽

Vis Spectroscopy ◽

Molar Ratio Method ◽

The Difference

A new Schiff base of 4- flourophenyl-4- nitrobenzyliden (L) ,was prepared and used to prepare a number of metal complexes with Cr (III) , Fe (III), Co(II) ,Ni (II) and Cu (II). These complexes were isolated and characterized by (FITR),UV-Vis spectroscopy and flame atomic absorption techniques in addition to magnetic susceptibility, and conductivity measurements. The study of the nature of the complexes formed in ethanol was done following the molar ratio method gave results, agreed with those obtained from isolated solid state studies. The antibacterial activity for the ligand and its metal complexes were examined against two selected microorganisms, Pseudomonas aeruginosa and Staphylococcus aureus.The results indicated that the complexes show the enhanced activity in comparison to the free ligand; these were attributed to the synergetic effect between the metal ion and the ligand in addition to the difference in the structural varieties.

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