Purulent Meningitis as an Unusual Presentation ofStaphylococcus aureusEndocarditis: A Case Report and Literature Review

On presentation ofStaphylococcus aureusendocarditis, unusual manifestations may represent the main clinical features of the disease. Isolated bacterial meningitis as the first manifestation of endocarditis is considered to be an unusual neurological complication. Here, we describe a caseS. aureusendocarditis presenting as isolated meningitis and mimicking meningococcal septicaemia. Because of the high mortality rate of the disease, the prompt recognition of this infectious syndrome is of crucial importance for the correct management of patients.

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Epidemiological characteristics of staphylococcal meningitis in Russian Federation

Medical alphabet ◽

10.33667/2078-5631-2021-18-51-54 ◽

2021 ◽

pp. 51-54

Author(s):

G. V. Beloshitskiy ◽

I. S. Koroleva ◽

M. A. Koroleva

Keyword(s):

Staphylococcus Aureus ◽

Mortality Rate ◽

Bacterial Meningitis ◽

Russian Federation ◽

Common Cause ◽

Probability Of Death ◽

The Russian Federation ◽

Epidemiological Characteristics

Staphylococcal meningitis (SM) ranks fourth in the etiological structure of purulent bacterial meningitis in the Russian Federation. The most common cause of staphylococcal meningitis is Staphylococcus aureus, which accounts for 68 % of all cases. This meningitis is characterized by a higher mortality rate (30 %) than staphylococcal meningitis of other types of Staphylococcus (13 %) and mainly affects people over 25 years of age. With increasing age, the probability of death increases, and among people over 65 years of age, the mortality rate reaches 44 %.

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Primary sternal osteomyelitis due to community-associated methicillin-resistant Staphylococcus aureus: case report and literature review

European Journal of Pediatrics ◽

10.1007/s00431-004-1511-0 ◽

2004 ◽

Author(s):

Min-Hua Tseng ◽

Wei-Jen Lin ◽

Ching-Shen Teng ◽

Chih-Chien Wang

Keyword(s):

Staphylococcus Aureus ◽

Case Report ◽

Literature Review ◽

Methicillin Resistant Staphylococcus Aureus ◽

Methicillin Resistant ◽

Sternal Osteomyelitis

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Intra-optic nerve and chiasmal abscess caused by methicillin-resistant Staphylococcus aureus (a case report and literature review)

Voprosy neirokhirurgii imeni N N Burdenko ◽

10.17116/neiro20188206189 ◽

2018 ◽

Vol 82 (6) ◽

pp. 89

Author(s):

O. F. Tropinskaya ◽

O. I. Sharipov ◽

O. N. Ershova ◽

P. L. Kalinin ◽

D. B. Ismailov

Keyword(s):

Staphylococcus Aureus ◽

Case Report ◽

Optic Nerve ◽

Literature Review ◽

Methicillin Resistant Staphylococcus Aureus ◽

Methicillin Resistant

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Chronic tuboovarian abscess due to Staphylococcus aureus: a case report and literature review

European Journal of Obstetrics & Gynecology and Reproductive Biology ◽

10.1016/0028-2243(89)90142-1 ◽

1989 ◽

Vol 33 (3) ◽

pp. 275-279 ◽

Cited By ~ 3

Author(s):

Dror Meirow ◽

Allon Moses ◽

Shlomo Maayan ◽

Joseph G. Schenker

Keyword(s):

Staphylococcus Aureus ◽

Case Report ◽

Literature Review ◽

Tuboovarian Abscess

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UBA1 and DNMT3A Mutations in VEXAS Syndrome. A Case Report and Literature Review

Modern Rheumatology Case Reports ◽

10.1093/mrcr/rxab021 ◽

2021 ◽

Author(s):

Farah Shaukat ◽

Melissa Hart ◽

Timothy Burns ◽

Pankaj Bansal

Keyword(s):

Bone Marrow ◽

Case Report ◽

Literature Review ◽

Gene Mutation ◽

Clinical Features ◽

Somatic Mutation ◽

Review Of Literature ◽

Unique Case ◽

Hematological Abnormalities ◽

Autoinflammatory Condition

Abstract VEXAS syndrome is a recently described X-linked autoinflammatory condition associated with somatic mutation of the UBA1 gene. It often coexists with MDS which can occur due to DNMT3A mutation. These patients, predominantly males, present after the fifth decade of life with unique systemic inflammatory clinical features and have hematological abnormalities and vacuolated precursor cells on bone marrow pathology. Here we describe a unique case of VEXAS syndrome in a patient harboring DNMT3A gene mutation with coexisting UBA1 mutation with a review of literature.

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