A Solvent-Free Protocol for the Green Synthesis of 5-Arylidene-2,4-thiazolidinediones Using Ethylenediamine Diacetate as Catalyst
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Work Up
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A simple and efficient synthesis of 5-arylidene-2,4-thiazolidinediones by the Knoevenagel condensation of aromatic aldehydes with 2,4-thiazolidinedione catalyzed by ethylenediamine diacetate under solvent-free conditions is described. The major advantages of this method are simple experimental and work-up procedures, solvent-free reaction conditions, small amount of catalyst, short reaction time, high yields, and utilization of an inexpensive and reusable catalyst.
2019 ◽
Vol 31
(6)
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pp. 1357-1361
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2020 ◽
Vol 23
(4)
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pp. 345-355
2019 ◽
Vol 16
(6)
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pp. 939-947
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2019 ◽
Vol 150
(12)
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pp. 2021-2023
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