Synthesis of amidoalkyl naphthols in PEG-400 as a green and efficient solvent and theoretical study of their spectroscopic properties

: An effectual synthesis of amidoalkyl naphthols from the multicomponent reaction of 2-naphthol, aromatic aldehydes, and benzamide derivatives using PEG-400 as an environmentally friendly solvent is described. The main advantage of this protocol is that low reactive benzamide derivatives such as 4-nitro benzamide can react effectively. Also, the molecular structure, IR, and 13C NMR spectra of the synthesized compounds are also investigated theoretically. Density functional theory (DFT) calculations at the B3LYP level of theory are carried out to locate optimized geometries and calculate normal vibrational modes and 13C NMR chemical shifts. These calculations enable us to assign the observed FT-IR and 13C NMR peaks to the corresponding vibrational motions and 13C atoms, respectively.

Correction: One-pot three-component synthesis of 1-amidoalkyl naphthols and polyhydroquinolines using a deep eutectic solvent: a green method and mechanistic insight

Correction for ‘One-pot three-component synthesis of 1-amidoalkyl naphthols and polyhydroquinolines using a deep eutectic solvent: a green method and mechanistic insight’ by Vu Thanh Nguyen et al., New J. Chem., 2021, 45, 2053–2059, DOI: 10.1039/d0nj05687a.

One-pot three-component synthesis of 1-amidoalkyl naphthols and polyhydroquinolines using deep eutectic solvent: A green method and mechanistic insight

The multicomponent synthesis of 1-amidoalkyl naphthols and polyhydroquinolines has been developed as an atom-economic procedure catalyzed by a deep eutectic solvent ([CholineCl][ZnCl2]3). The reactions proceed smoothly at low temperatures for...