scholarly journals Gastric Schwannoma: A Rare but Important Differential Diagnosis of a Gastric Submucosal Mass

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
William Yoon ◽  
Kari Paulson ◽  
Paul Mazzara ◽  
Sweety Nagori ◽  
Mohammed Barawi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Surgical Resection ◽  
Treatment Options ◽  
Partial Gastrectomy ◽  
Preoperative Imaging ◽  
Mesenchymal Tumors ◽  
Gastric Schwannoma ◽  
Gastric Mass ◽  
Submucosal Mass ◽  
Slow Growing

Schwannomas are generally slow growing asymptomatic neoplasms that rarely occur in the GI tract. However, if found, the most common site is the stomach. Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, and 60–70% of them occur in the stomach. Owing to their typical presentation as submucosal neoplasms, gastric schwannomas and GISTs appear grossly similar. Accordingly, the differential diagnosis for a gastric submucosal mass should include gastric schwannomas. Furthermore, GI schwannomas are benign neoplasms with excellent prognosis after surgical resection, whereas 10–30% of GISTs have malignant behavior. Hence, it is important to distinguish gastric schwannomas from GISTs to make an accurate diagnosis to optimally guide treatment options. Nevertheless, owing to the paucity of gastric schwannomas, the index of suspicion for this diagnosis is low. We report a rare case of gastric schwannoma in 53-year-old woman who underwent laparoscopic partial gastrectomy under the suspicion of a GIST preoperatively but confirmed to have a gastric schwannoma postoperatively. This case underscores the importance of including gastric schwannomas in the differential diagnosis when preoperative imaging studies reveal a submucosal, exophytic gastric mass. For a gastric schwannoma, complete margin negative surgical resection is the curative treatment of choice.

scholarly journals Gastric Schwannoma mimicking gastrointestinal stromal tumors: a rare case with review of literature

2020 ◽  
Vol 7 (5) ◽  
pp. 1691
Author(s):  
Nagari Bheerappa ◽  
Digvijoy Sharma ◽  
Gangadhar Rao Gondu ◽  
Nirjhar Raj ◽  
Kamal Kishore Bishnoi ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Gastrointestinal Stromal Tumors ◽  
Malignant Potential ◽  
Review Of Literature ◽  
Mesenchymal Tumors ◽  
Submucosal Tumors ◽  
Stromal Tumors ◽  
Gastric Schwannoma ◽  
Gastric Mass ◽  
Slow Growing

Gastric schwannoma (GS) is a rare neoplasm of the stomach. It accounts for 0.2% of all gastric tumors and is mostly benign, slow-growing, and asymptomatic. Gastrointestinal stromal tumors (GIST) are the most common mesenchymal tumors and up to 60-70% of GIST occur in the stomach. Schwannoma and GIST have similar radiological and endoscopic features making it extremely difficult to differentiate them preoperatively. Differential diagnosis of these two submucosal tumors is important because of the malignant potential of GIST and the relatively benign course of gastric schwannomas. This case stresses on the importance of including gastric schwannomas in the differential diagnosis of a submucosal gastric mass as it has the ability to mimic a gastrointestinal stromal tumor, which is a leading differential diagnosis because of its common occurrence at this site.

scholarly journals Gastric schwannoma: a benign tumor often misdiagnosed as gastrointestinal stromal tumor

2015 ◽  
Vol 5 (3) ◽  
Author(s):  
Apurva S. Shah ◽  
Pravin M. Rathi ◽  
Vaibhav S. Somani ◽  
Astha M. Mulani
Keyword(s):  
Differential Diagnosis ◽  
Gastrointestinal Stromal Tumor ◽  
Gastrointestinal Stromal Tumors ◽  
Rare Case ◽  
Benign Tumor ◽  
Stromal Tumor ◽  
Mesenchymal Tumors ◽  
Stromal Tumors ◽  
Gastric Schwannoma ◽  
Gastric Mass

Gastric schwannomas are rare mesenchymal tumors that arise from the nerve plexus of gut wall. They present with nonspecific symptoms and are often detected incidentally. Preoperative investigation is not pathognomic and many are therefore misdiagnosed as gastrointestinal stromal tumors. We report a rare case of a 37-year old woman who underwent laparotomy for complex bilateral ovarian cyst with resection of gastric-gastrointestinal stromal tumor preoperatively, but confirmed to have a gastric schwannomas postoperatively. This case underscores the differential diagnosis of submucosal, exophytic gastric mass as schwannoma.

scholarly journals Gastric Schwannoma

2018 ◽  
Vol 36 (2) ◽  
pp. 157
Author(s):  
Tanawat Pattarapuntakul
Keyword(s):  
Incidental Finding ◽  
Abdominal Mass ◽  
Mesenchymal Tumors ◽  
Cross Sectional ◽  
Presenting Symptoms ◽  
Gastric Schwannoma ◽  
Cross Sectional Imaging ◽  
Slow Growing ◽  
Radiology And Pathology ◽  
Upper Gastrointestinal

A gastric schwannoma is a rare primary spindle cell mesenchymal tumor of the digestive tract. Gastric schwannomas originate from Schwann cells of the peripheral nerves in the stomach. The majority of schwannomas are benign, slow growing tumors only a few of which develop into malignancies. Due to their indolent course, in most cases, gastric schwannomas are asymptomatic or discovered as an incidental finding on cross-sectional imaging or endoscopy. When symptomatic, the most common presenting symptoms are abdominal pain, upper gastrointestinal bleeding and intra- abdominal mass. Preoperatively, gastric schwannomas are difficult to differentiate from other mesenchymal tumors, such as gastrointestinal stroma or leiomyoma which develop from mesenchymal stem cells. The optimal management of the tumor is based on the symptoms of the patient, tumor size and histologic grading and the prognosis is excellent after complete surgical or endoscopic removal. Gastric schwannomas need multidisciplinary team management for definitive diagnosis and management, including specialists from gastroenterology, surgery, radiology and pathology.

scholarly journals Primary Intrathoracic Goiter

2009 ◽  
Vol 1 (1) ◽  
pp. 43-46
Author(s):  
Dorin T Colibaseanu ◽  
Jon A van Heerden ◽  
David R Farley ◽  
Stephen D Cassivi
Keyword(s):  
Differential Diagnosis ◽  
Thyroid Gland ◽  
Surgical Resection ◽  
Mediastinal Mass ◽  
Treatment Options ◽  
Radiographic Imaging ◽  
Intrathoracic Goiter ◽  
Transcervical Approach ◽  
Substernal Goiter ◽  
Mediastinal Goiter

ABSTRACT The differential diagnosis of a middle mediastinal mass is fairly broad. Though relatively rare, the diagnosis of primary intrathoracic goiter is a clinically important consideration that should not be overlooked. The nature of this clinical entity and its diagnostic implications are discussed. Relevant radiographic imaging is evaluated demonstrating the key findings. Indications for intervening and treatment options are reviewed. Specifically, the presence of a growing substernal goiter in an otherwise fit patient is generally an indication for surgical resection. The nature of a primary intrathoracic goiter usually obviates the more common transcervical approach since by definition the mediastinal goiter is discontinuous with the cervical thyroid gland. Other transthoracic approaches are therefore necessary.

scholarly journals Gastric Schwannoma: A Postoperative Surprise A Case Report.

2014 ◽  
Vol 1 (1) ◽  
pp. 23-25
Author(s):  
Abdelmounaim Ait ALi ◽  
Mohamed Essarghini ◽  
Abderzak Hajjouji ◽  
Khalid Sair
Keyword(s):  
Case Report ◽  
Clinical Case ◽  
Submucosal Tumor ◽  
S100 Protein ◽  
Partial Gastrectomy ◽  
Definitive Diagnosis ◽  
Resected Specimen ◽  
Stromal Tumors ◽  
Gastric Schwannoma ◽  
Slow Growing

Gastric Schwannoma is a rare, slow-growing, and clinically non-specific submucosal tumor, originating from Schwann cells with excellent prognosis after surgical resection. We report a clinical case of a patient presented with gastric schwannoma revealed by non-specific gastric signs and of which the definitive diagnosis is done through immunohistochemistry of the resected specimen, showing strong S100 protein positivity. The evolution is favorable after a partial gastrectomy with a decline of two years. Through this case, we are trying to trace the rarity, strong similarities with gastric stromal tumors and especially, the weak index of suspicion for this diagnosis.

scholarly journals Gastric Schwannoma: A Case Report and Review of the Literature for Gastric Submucosal Masses Distinction

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Behnam Sanei ◽  
Amirhosein Kefayat ◽  
Melika Samadi ◽  
Parvin Goli ◽  
Mohammad Hossein Sanei ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumors ◽  
Rare Case ◽  
Outlet Obstruction ◽  
Accurate Diagnosis ◽  
Review Of The Literature ◽  
Stromal Tumors ◽  
Gastric Schwannoma ◽  
Frequent Vomiting ◽  
Submucosal Mass ◽  
Slow Growing

Schwannomas origin from Schwann cells sheath and generally are benign, slow-growing, and asymptomatic neoplasms which frequently appear in the head and neck. Although gastrointestinal schwannoma is really rare, the most affected organ in GI system is the stomach. Gastric schwannoma forms 0.2% of all gastric tumors. This neoplasm is always detected as a submucosal mass, the same as other gastrointestinal stromal tumors. Although these tumors have almost the same presentations, they are completely different at therapeutic options and prognoses. Hence, it is important to distinguish them apart and make an accurate diagnosis to optimize treatment outcomes. Herein, we report a case of 28-year-old woman with frequent vomiting and abdominal pain caused by 5 × 6 cm schwannoma in the antrum of the stomach. This is a rare case of gastric outlet obstruction due to a massive schwannoma. In addition, all other probable submucosal masses will be discussed at different aspects.

scholarly journals Gastric Schwannoma

2018 ◽  
Vol 36 (2) ◽  
pp. 157
Author(s):  
Tanawat Pattarapuntakul
Keyword(s):  
Incidental Finding ◽  
Abdominal Mass ◽  
Mesenchymal Tumors ◽  
Cross Sectional ◽  
Presenting Symptoms ◽  
Gastric Schwannoma ◽  
Cross Sectional Imaging ◽  
Slow Growing ◽  
Radiology And Pathology ◽  
Upper Gastrointestinal

A gastric schwannoma is a rare primary spindle cell mesenchymal tumor of the digestive tract. Gastric schwannomas originate from Schwann cells of the peripheral nerves in the stomach. The majority of schwannomas are benign, slow growing tumors only a few of which develop into malignancies. Due to their indolent course, in most cases, gastric schwannomas are asymptomatic or discovered as an incidental finding on cross-sectional imaging or endoscopy. When symptomatic, the most common presenting symptoms are abdominal pain, upper gastrointestinal bleeding and intra- abdominal mass. Preoperatively, gastric schwannomas are difficult to differentiate from other mesenchymal tumors, such as gastrointestinal stroma or leiomyoma which develop from mesenchymal stem cells. The optimal management of the tumor is based on the symptoms of the patient, tumor size and histologic grading and the prognosis is excellent after complete surgical or endoscopic removal. Gastric schwannomas need multidisciplinary team management for definitive diagnosis and management, including specialists from gastroenterology, surgery, radiology and pathology.

scholarly journals Case reports on a gastric mass presenting with regional lymphadenopathy: A differential diagnosis is gastric schwannoma

2020 ◽  
Vol 72 ◽  
pp. 369-372
Author(s):  
Arnav Wadhawan ◽  
Maureen Brady ◽  
Charles LeVea ◽  
Steven Hochwald ◽  
Moshim Kukar
Keyword(s):  
Differential Diagnosis ◽  
Case Reports ◽  
Gastric Schwannoma ◽  
Gastric Mass

scholarly journals Gastric schwannoma: a diagnosis that should be known in 2019

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
Massama Lomdo ◽  
Khadija Setti ◽  
Mohamed Oukabli ◽  
Mountassir Moujahid ◽  
Ahmed Bounaim
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Schwann Cells ◽  
Peripheral Nerves ◽  
Gastric Resection ◽  
Immunohistochemical Study ◽  
Optimal Management ◽  
Mesenchymal Tumors ◽  
Gastric Schwannoma ◽  
Slow Growing

Abstract Gastric schwannoma (GS) is a rare neoplasm of the stomach deriving from Schwann cells of the peripheral nerves in the stomach. It accounts for 0.2% of all gastric tumors and is mostly benign, slow-growing and asymptomatic. Due to its rarity, GS is not widely recognized by clinicians. Preoperatively, GSs are difficult to differentiate from other mesenchymal tumors, such as gastrointestinal stromal tumor (GIST) or leiomyoma, which develop from mesenchymal stem cells. The optimal management of GS is based on the symptoms of the patient, tumor size and histologic grading. Here, we report the case of a GS in a 73-year-old female who underwent a wedge gastric resection following a clinical diagnosis of GIST. A histological and immunohistochemical study was performed excluding the misdiagnosis of GIST. The histomorphological features of the lesion and absence of c-Kit and strong positivity of S100 indicated the diagnosis of GS.

scholarly journals The lipomatosis of the parapharyngeal and retropharyngeal space: A case report

2015 ◽  
Vol 143 (7-8) ◽  
pp. 455-457 ◽  
Author(s):  
Klaudiusz Luczak ◽  
Karolina Dorobisz ◽  
Tomasz Krecicki ◽  
Dariusz Janczak ◽  
Mariusz Chabowski ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Sleep Apnea ◽  
Soft Tissue ◽  
Soft Tissue Tumors ◽  
Retropharyngeal Space ◽  
Respiratory Obstruction ◽  
Mesenchymal Tumors ◽  
Slow Growing ◽  
Progressive Dysphagia

Introduction. Lipomas are the most common benign mesenchymal tumors, which account for almost 50% of all soft-tissue tumors. Case Outline. The case of a 75-year-old patient with a slow growing lesion of para- and retropharyngeal space was reported. The patient was suffering from progressive dysphagia, respiratory obstruction and sleep apnea. Conclusion. An external surgical approach is the treatment of choice. Etiology, differential diagnosis and therapy of head and neck lipomas has been discussed.

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