Multilayer Films Electrodes Consisted of Cashew Gum and Polyaniline Assembled by the Layer-by-Layer Technique: Electrochemical Characterization and Its Use for Dopamine Determination

We take advantage of polyelectrolyte feature exhibited by natural cashew gum (Anacardium occidentaleL.) (CG), found in northeast Brazil, to employ it in the formation of electroactive nanocomposites prepared by layer-by-layer (LbL) technique. We used polyaniline unmodified (PANI) or modified with phosphonic acid (PA), PANI-PA as cationic polyelectrolyte. On the other hand, the CG or polyvinyl sulfonic (PVS) acids were used as anionic polyelectrolytes. The films were prepared with PANI or PANI-PA intercalated with CG or with PVS alternately resulting in four films with different sequences: PANI/CG PANI-PA/CG, PANI/PVS and PANI-PA/PVS, respectively. Analysis by cyclic voltammetry (CV) of the films showed that the presence of gum increases the stability of the films in acidic medium. The performance of the modified electrode of PANI-PA/CG was evaluated in electro analytical determination of dopamine (DA). The tests showed great sensitivity of the film for this analyte that was detected at 10−5 mol L−1.

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A novel inhibition biosensor constructed by layer-by-layer technique based on biospecific affinity for the determination of sulfide

Sensors and Actuators B Chemical ◽

10.1016/j.snb.2007.07.137 ◽

2008 ◽

Vol 129 (1) ◽

pp. 218-224 ◽

Cited By ~ 41

Author(s):

Lijun Liu ◽

Zhichun Chen ◽

Shaoming Yang ◽

Xin Jin ◽

Xianfu Lin

Keyword(s):

Layer By Layer ◽

Layer Technique ◽

Layer By Layer Technique

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Horseradish peroxidase biosensor based on layer-by-layer technique for the determination of phenolic compounds

Sensors and Actuators B Chemical ◽

10.1016/j.snb.2005.07.035 ◽

2006 ◽

Vol 114 (2) ◽

pp. 774-780 ◽

Cited By ~ 58

Author(s):

Shaoming Yang ◽

Yangmei Li ◽

Xiuming Jiang ◽

Zhichun Chen ◽

Xianfu Lin

Keyword(s):

Phenolic Compounds ◽

Horseradish Peroxidase ◽

Layer By Layer ◽

Layer Technique ◽

Layer By Layer Technique

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Simultaneous determination of ascorbic acid, dopamine and uric acid using polystyrene sulfonate wrapped multiwalled carbon nanotubes bound to graphite electrode through layer-by-layer technique

Sensors and Actuators B Chemical ◽

10.1016/j.snb.2010.01.011 ◽

2010 ◽

Vol 145 (2) ◽

pp. 643-650 ◽

Cited By ~ 82

Author(s):

Revanasiddappa Manjunatha ◽

Gurukar Shivappa Suresh ◽

Jose Savio Melo ◽

Stanislaus F. D'Souza ◽

Thimmappa Venkatarangaiah Venkatesha

Keyword(s):

Carbon Nanotubes ◽

Ascorbic Acid ◽

Uric Acid ◽

Graphite Electrode ◽

Layer By Layer ◽

Polystyrene Sulfonate ◽

Multiwalled Carbon ◽

Layer Technique ◽

Layer By Layer Technique

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Determination of fluoroquinolone antibiotics through the fluorescent response of Eu(III) based nanoparticles fabricated by layer-by-layer technique

Analytica Chimica Acta ◽

10.1016/j.aca.2013.04.054 ◽

2013 ◽

Vol 784 ◽

pp. 65-71 ◽

Cited By ~ 19

Author(s):

Nikolay Davydov ◽

Rustem Zairov ◽

Asiya Mustafina ◽

Viktor Syakayev ◽

Dmitry Tatarinov ◽

...

Keyword(s):

Layer By Layer ◽

Fluoroquinolone Antibiotics ◽

Fluorescent Response ◽

Layer Technique ◽

Layer By Layer Technique

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Layer-by-layer technique for enhancing physicochemical properties of actives

Journal of Drug Delivery Science and Technology ◽

10.1016/j.jddst.2020.101519 ◽

2020 ◽

Vol 56 ◽

pp. 101519

Author(s):

Pravin Shende ◽

Amar Patil ◽

Bala Prabhakar

Keyword(s):

Physicochemical Properties ◽

Layer By Layer ◽

Layer Technique ◽

Layer By Layer Technique

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Pectin-Chitosan Multilayer Coated Microbeads of Diclofenac Sodium Prepared by Layer-by-Layer Technique

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.1060.45 ◽

2014 ◽

Vol 1060 ◽

pp. 45-49

Author(s):

Kamonrak Cheewatanakornkool ◽

Pornsak Sriamornsak

Keyword(s):

Controlled Release ◽

Drug Release ◽

Diclofenac Sodium ◽

Gastric Fluid ◽

Layer By Layer ◽

Release Behavior ◽

Freeze Dried ◽

Layer Technique ◽

Calcium Pectinate ◽

Layer By Layer Technique

The main objective of this study was to fabricate biopolymer-based microbeads, providing enteric properties and controlled release of diclofenac sodium, using layer-by-layer technique. The calcium pectinate microbeads have been designed and coated with chitosan and pectin multilayers. Drug release was performed in simulate gastric fluid (pH 1.2) for 2 hours, followed by pH 6.8 buffer for 8 hours. The effects of chitosan concentration, number of layer and drying technique on drug release were investigated. The results showed that the calcium pectinate microbeads could be simply prepared by ionotropic gelation and then coated with chitosan and pectin solutions using layer-by-layer procedure. The diameter of the microbeads ranged from 800 to 1000 μm for air-dried samples and from 1 to 2 mm for freeze-dried samples. The freeze-dried microbeads had a rough surface and many pores inside, as observed by SEM. The microbeads coated with 4% chitosan/4% pectin revealed a slower drug release than those coated with 1% chitosan/4% pectin and demonstrated a controlled release pattern. Moreover, different drying techniques and numbers of layer also influenced drug release behavior of the prepared microbeads.

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