scholarly journals An Unusual Granular Cell Tumour of the Buttock and a Review of Granular Cell Tumours

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
Sharad P. Paul ◽  
Vladimir Osipov
Keyword(s):  
Clinical Case ◽  
Clinical Presentation ◽  
White Male ◽  
Granular Cell ◽  
Cell Tumour ◽  
Soft Tissue Tumour ◽  
Granular Cell Tumour ◽  
Tissue Tumour ◽  
Granular Cell Tumours ◽  
The Mean

Granular cell tumours, first described by Abrikossoff in 1926, are known to occur in skin, connective tissue, breast, gastrointestinal and genital tracts. While they are rare, they are more common in people of African descent and show a slight female preponderance, usually presenting as solitary and painless masses. Less than 10% of occurrences are multiple, and fewer than 3% of tumours behave in a malignant fashion. The mean age, at presentation, is 40–60 years. We report a case of granular cell tumour in a young white male presenting with a painful soft tissue tumour in his buttock. The presentation is unusual because of the age, patient demographic, body site, and clinical presentation. The clinical and histological aspects are reviewed in the context of this clinical case and the associated literature.

scholarly journals Gastric granular cell tumour, a rare entity

2019 ◽  
Vol 12 (3) ◽  
pp. e227510
Author(s):  
Cláudia Santos ◽  
Ana Virgínia Araújo ◽  
Helena Contente ◽  
Cláudia Branco
Keyword(s):  
Oral Cavity ◽  
Surgical Resection ◽  
Clinical Case ◽  
Subcutaneous Tissue ◽  
Granular Cell ◽  
The Body ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Rare Entity ◽  
Granular Cell Tumours

Granular cell tumours are rare neoplasms that may occur anywhere in the body. The most common locations are the oral cavity, skin and subcutaneous tissue, with only 8% of these tumours occurring at a gastrointestinal site. In the specific case of gastric granular cell tumours, only a few cases have been published until today. Granular cell tumours are usually benign; however, some malignant forms have been reported. Both endoscopic and surgical resection represent the treatment of choice. The authors report a new clinical case of a gastric granular cell tumour, treated with laparoscopic surgical resection, describing some endoscopic, imagiological and anatomopathological features.

scholarly journals Granular Cell Tumours: A Rare Entity in the Musculoskeletal System

Sarcoma ◽  
2009 ◽  
Vol 2009 ◽  
pp. 1-4 ◽  
Author(s):  
Barry Rose ◽  
George S. Tamvakopoulos ◽  
Eric Yeung ◽  
Robin Pollock ◽  
John Skinner ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Case Series ◽  
Immunohistochemical Analysis ◽  
Granular Cell ◽  
The Body ◽  
Soft Tissue Tumour ◽  
Granular Cell Tumour ◽  
Tissue Tumour ◽  
Neural Origin ◽  
Granular Cell Tumours

Granular Cell Tumours are rare mesenchymal soft tissue tumours that arise throughout the body and are believed to be of neural origin. They often present as asymptomatic, slow-growing, benign, solitary lesions but may be multifocal. 1-2% of cases are malignant and can metastasise. Described series in the literature are sparse. We identified eleven cases in ten patients treated surgically and followed-up for a period of over 6 years in our regional bone and soft tissue tumour centre. Five tumours were located in the lower limb, four in the upper limb, and two in the trunk. Mean patient age was 31.2 years (range 8–55 years). Excision was complete in one case, marginal in five cases and intralesional in five cases. No patients required postoperative adjuvant treatment. Mean follow-up was 19.3 months (range 1–37 months). One case was multifocal, but there were no cases of local recurrence or malignancy. Histopathological and immunohistochemical analysis revealed the classical granular cell tumour features in all cases. We believe this case series to be the largest of its type in patients presenting to an orthopaedic soft tissue tumour unit. We present our findings and correlate them with findings of other series in the literature.

Granular cell tumour of the larynx in an eight-year-old girl

1993 ◽  
Vol 107 (10) ◽  
pp. 940-941 ◽  
Author(s):  
Abdalla M. Hamid ◽  
Abduljabbar Alshaikly
Keyword(s):  
Local Excision ◽  
Black People ◽  
Benign Neoplasm ◽  
Granular Cell ◽  
The Body ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Multiple Lesions ◽  
Granular Cell Tumours

AbstractGranular cell tumour is a rare benign neoplasm, that can affect many parts of the body, as single or multiple lesions. It is more common in black people and females. Typically it occurs between the fourth and fifth decades of life, with the median age for the laryngeal variety as 36 years. About 30 to 50 per cent occur in the tongue and 30 per cent in the skin.A case of granular cell tumour of the larynx is reported in an eight-year-old girl, presenting with hoarseness of voice. She was successfully treated with local excision of the tumour. This tumour is rare in the larynx where it is more common in males than females although granular cell tumours are found more frequently in females generally.For these reasons the authors suspect that their case, of a laryngeal granular cell tumour occurring in an eight-year-old girl might be the youngest to be reported.

scholarly journals Case Series: Two Cases of an Atypical Presentation of Oral Granular Cell Tumour

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Emma Cole ◽  
Naomi Rahman ◽  
Roger Webb
Keyword(s):  
Soft Tissue ◽  
Clinical Presentation ◽  
Case Series ◽  
Granular Cell ◽  
Granular Cell Tumour ◽  
Atypical Presentation ◽  
Recurrence Rates ◽  
Soft Tissue Neoplasm ◽  
Atypical Clinical Presentation ◽  
Granular Cell Tumours

This paper describes two cases of oral granular cell tumours with an atypical clinical presentation; both are in females aged between 45 and 63 years of age. Granular cell tumours are unusual soft tissue neoplasm of neural or Schwann cell origin. Oral GCTs usually present clinically as pink or yellow small sessile lesions. GCTs are usually benign in nature; however they can present in a malignant form in fewer than 2% of cases. In benign cases treatment is surgical and usually curative with extremely low recurrence rates.

scholarly journals Granular Cell Tumour of The Vulva: A Case Report

1970 ◽  
Vol 3 (1) ◽  
pp. 28-30
Author(s):  
SM Khodeza ◽  
Nahar Begum ◽  
Nishat Begum
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Benign Lesion ◽  
Granular Cell ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Duct Cyst ◽  
Clinical Presentations ◽  
Neural Origin ◽  
Granular Cell Tumours

Vulvar granular cell tumours are uncommon neoplasms of neural origin. The clinical presentations, surgical findings and histology of Granular Cell Tumour (GCT) of the vulva in a 50 year old lady is presented. Although rare, this benign lesion must be considered in the differential diagnosis of the labia majora masses, such as Bartholin,s duct cyst, Lipoma, Papilloma, Hydradenoma and Fibroma. DOI: http://dx.doi.org/10.3329/akmmcj.v3i1.10111 AKMMCJ 2012; 3(1): 28-30

scholarly journals Granular cell tumour of the breast: A rare presentation of a breast mass in an elderly female with a subsequent breast cancer diagnosis

2019 ◽  
Vol 7 ◽  
pp. 2050313X1984115
Author(s):  
Mahmoud Al-Balas ◽  
Antonio De Leo ◽  
Margherita Serra ◽  
Donatella Santini ◽  
Mario Taffurelli
Keyword(s):  
Granular Cell ◽  
Breast Cancer Diagnosis ◽  
Clinical Suspicion ◽  
Cell Tumour ◽  
Breast Mass ◽  
Histological Evaluation ◽  
Granular Cell Tumour ◽  
Rare Presentation ◽  
Elderly Female ◽  
Granular Cell Tumours

A 74-year-old female patient presented with a hard breast mass and dimpling with a clinical suspicion of a carcinoma. Histological evaluation revealed a granular cell tumour. Granular cell tumour is a rare neoplasm, mostly benign in origin that may arise in every body site, 5%–15% of cases occur in the breast. It is strongly suggested that granular cell tumours origin is Schwann cells. Clinically, granular cell tumours presentation may mimic mammary carcinoma and their similar features on mammography and ultrasound make it difficult to differentiate between them.

scholarly journals Granular Cell Tumour of the Breast Cancer: Challenging Clinical and Radiological Mimic of Cancer

2012 ◽  
Vol 12 (1) ◽  
pp. 84-86
Author(s):  
Arnis Abolins ◽  
Ilze Strumfa ◽  
Andrejs Vanags ◽  
Genadijs Trofimovics ◽  
Janis Gardovskis
Keyword(s):  
Breast Cancer ◽  
Soft Tissue ◽  
Granular Cell ◽  
Soft Tissue Neoplasms ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Granular Cell Tumours

SummaryGranular cell tumours (GCT) are rare soft tissue neoplasms of unclear histogenesis affecting almost any organ or tissues. Approximately 5% of GCT cases are located in the breast. Although granular cell tumour is benign in most instances, it can mimic breast cancer by radiological and clinical traits. Increased awareness of GCT is necessary to avoid misinterpretation as cancer and subsequent overtreatment

Granular Cell Tumour of the Ulnar Nerve

1999 ◽  
Vol 24 (1) ◽  
pp. 122-124 ◽  
Author(s):  
T. YASUTOMI ◽  
H. KOIKE ◽  
Y. NAKATSUCHI
Keyword(s):  
Peripheral Nerve ◽  
Ulnar Nerve ◽  
Granular Cell ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Nerve Fibres ◽  
Neural Origin ◽  
Granular Cell Tumours

Although granular cell tumours have been demonstrated to have a neural origin, they rarely arise in peripheral nerve trunks. We report a case of granular cell tumour of the ulnar nerve in a 51-year-old man. Though dissectable from the nerve, this intraneural tumour showed microscopic involvement of focal nerve fibres. This tumour tended to infiltrate the nerve in the same manner as a neurofibroma.

scholarly journals Synchronous subcutaneous granular cell tumours, a rare presentation

2018 ◽  
Vol 100 (4) ◽  
pp. e85-e87
Author(s):  
A Goetz ◽  
N Nweze ◽  
A Joshi ◽  
J Farma
Keyword(s):  
Frozen Section ◽  
Immunohistochemical Analysis ◽  
Granular Cell ◽  
Mitotic Rate ◽  
Left Breast ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Rare Presentation ◽  
Granular Cell Tumours ◽  
The Masses

We describe a unique presentation of a rare disease presentation of a granular cell tumour. A 36-year-old woman presents with a large symptomatic left flank mass that had been slowly increasing in size. Multiple synchronous subcutaneous masses were found at presentation on the left breast, right auricle and right cheek. After diagnosis of granular cell tumour by core needle biopsy, the masses were excised with histopathological and immunohistochemical analysis of both specimens confirming the presence of non-malignant granular cell tumours. Granular cell tumours are rare Schwann cell derived tumours that are typically asymptomatic and benign. These tumours are most often located in the head and neck, with multifocal disease present in approximately 5–16% of patients. Final pathology is necessary for diagnosis and frozen section is rarely helpful. Malignancy is present in approximately 2% of cases and can be diagnosed by the presence of a high mitotic rate, large nucleoli, necrosis, spindling and pleomorphism are other suspicious features. Granular cell tumours do not generally require adjuvant treatment. The mainstay of therapy is surgical resection with surveillance.

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