scholarly journals Availability of Tongue Diagnosis System for Assessing Tongue Coating Thickness in Patients with Functional Dyspepsia

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Juyeon Kim ◽  
Jiyoung Son ◽  
Seungwon Jang ◽  
Dong-Hyun Nam ◽  
Gajin Han ◽  
...  

Tongue diagnosis is an important procedure in traditional Korean medicine (TKM). In particular, tongue coating thickness (TCT) is deemed to show the progression of the disease. However, conventional tongue diagnosis has limitations because of various external factors. Therefore, it is necessary to investigate the availability of tongue diagnosis system (TDS) in the assessment of TCT. This study has been designed as a prospective clinical trial involving 60 patients with functional dyspepsia. Tongue images will be obtained by TDS twice with a 30 min interval. The system will measure the percentage of TCT and classify it as either no coating, thin coating, or thick coating according to the existing diagnostic criteria. After finishing the collection of 60 patients' tongue images, TCT on the images will be simultaneously evaluated by the conventional method to establish the gold standard for assessing TCT by 5 well-trained clinicians. The evaluation will be repeated by the same clinicians after 2 weeks, but the order of the images will be changed. This trial is expected to provide clinical evidence for the availability of TDS as a diagnostic tool and to contribute to the standardization of the diagnosis system used in TKM. This trial is registered with ClinicalTrials.govNCT01864837.

2014 ◽  
Vol 155 (1) ◽  
pp. 709-713 ◽  
Author(s):  
Juyeon Kim ◽  
Gajin Han ◽  
Seok-Jae Ko ◽  
Dong-Hyun Nam ◽  
Jae-Woo Park ◽  
...  

Medicine ◽  
2019 ◽  
Vol 98 (28) ◽  
pp. e16106
Author(s):  
Jihye Kim ◽  
Jiwon Kim ◽  
Inkwon Yeo ◽  
Juyeon Kim ◽  
Jinsung Kim ◽  
...  

2012 ◽  
Vol 20 (5) ◽  
pp. 316-322 ◽  
Author(s):  
Jinsung Kim ◽  
Ga-Jin Han ◽  
Bin-Hye Choi ◽  
Jae-Woo Park ◽  
Kyungmo Park ◽  
...  

2017 ◽  
Vol 25 (3) ◽  
pp. 191-197 ◽  
Author(s):  
Shipeng Sun ◽  
Huamin Wei ◽  
Ruili Zhu ◽  
Bo Pang ◽  
Shuming Jia ◽  
...  

Tongue diagnosis is one of the most important diagnostic tools in traditional Chinese medicine and has been verified for thousands of years. However, its subjectivity and repeatability has been disputed continuously. The tongue coating as the primary coverage of tongue diagnosis provides more objectivity and reproducibility due to its relatively clear molecular basis; it also has a close relationship with many system diseases and may be used as a potentially valuable disease diagnostic tool. This article describes the material basis of the tongue coating, including its biology (epithelial cells, blood cells, vascular endothelial cells, and bacteria) and its metabolites; moreover, we summarize the diseases that are most correlated with the tongue coating. This will be valuable not only for fundamental research of tongue diagnosis but also for the diagnosis and differential diagnosis of disease. We suppose that the tongue coating could serve as a valuable auxiliary diagnosis tool in many diseases, and more research should focus on how to colligate the various information about the tongue and provide useful information for disease diagnosis.


2020 ◽  
Author(s):  
Min-Jee Kim ◽  
Shambhunath Bose ◽  
Na Rae Shin ◽  
Meng Yang ◽  
Ojin Kwon ◽  
...  

Abstract Background Cheonwangbosim-dan (CBD) is a traditional Korean herb formula that has been widely prescribed for insomnia patients with a heart-yin deficiency (HYD) pattern. Several studies have recently reported that heart function and insomnia are interrelated, and others have explored associations between insomnia, oral microbiota, and tongue diagnosis. This study aimed to evaluate the effects of CBD on primary insomnia, tongue diagnosis, and oral microbiota. We conducted a prospective, open-label clinical trial on primary insomnia. At baseline, 56 patients with primary insomnia were assigned to two groups, a HYD group and a non-HYD (NHYD) group. Members of these groups took CBD for 6 weeks. Primary and secondary outcomes including Pittsburgh Sleep Quality Indices (PSQIs), Insomnia Severity Indices (ISIs), actigraphy results, cardiac function, autonomic nerve function, clinical laboratory results, tongue features, and oral microbiota were collected from all subjects at after 0, 3, or 6 weeks of treatment. Additionally, PSQI and ISI were determined by telephone follow-up 10 weeks after study commencement.Results During the study, PSQIs and ISIs decreased significantly in both groups. However, the PSQI reduction observed in the HYD group was greater than in the NHYD group and sleep times as determined by actigraphy, that is, total bedtimes (TBTs) and total sleep times (TST), increased only in the HYD group. As sleep quality improved, the amount of tongue coating increased at the posterior tongue, where heart function appears. At baseline, the HYD and NHYD group had a specific oral microbiota (Veillonella at genus level), but no significant change was observed after taking CBD. Additionally, subjects were divided into two oral microbiota types (‘orotype’). The genera Prevotella, Veillonella or Neisseria were abundant in each orotype. The reduction in PSQI in the orotype 1 during the 6-week treatment period was greater than in orotype 2.Conclusions Taking together, CBD was effective in primary insomnia patients with a HYD pattern and CBD increased the amount of tongue coating. In addition, oral microbiota distributions were different in patients with a HYD or a NHYD pattern. The study shows CBD could be used to treat primary insomnia in patients with a HYD pattern as determined using tongue diagnosis and oral microbiota distributional patterns.


2012 ◽  
Vol 155-156 ◽  
pp. 133-137
Author(s):  
Li Ping Wang ◽  
Hao Dong Luo ◽  
Yan Mei Cui

It is necessary to study the mechanics performance of thin coating, which composite the prerequisite of coating’s application. The contact stresses are important factors for the design of hard coating/substrate because the failure of the hard coating is usually caused by these stresses. The finite element method is applied to simulate the stress of coating with contact load based on Hertz contact theory. The accuracy of model was initially tested in systems without a film. The contact stresses have been calculated based on various coating/substrate modulus ratios and the coating thickness. Results show that coating thickness changes from 1.5um to 3um, the effects of coating/substrate combination is perfect. The research has important guiding significance for the application of coating.


2013 ◽  
Vol 18 (4) ◽  
pp. 45-55
Author(s):  
Jin-Woong Park ◽  
Sun-Kyung Kang ◽  
Young-Un Kim ◽  
Sung-Tae Jung

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