scholarly journals Exploring Antiurolithic Effects of Gokshuradi Polyherbal Ayurvedic Formulation in Ethylene-Glycol-Induced Urolithic Rats

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Amol L. Shirfule ◽  
Venkatesh Racharla ◽  
S. S. Y. H. Qadri ◽  
Arjun L. Khandare
Keyword(s):  
Ethylene Glycol ◽  
Calcium Oxalate ◽  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Biochemical Parameters ◽  
Underlying Mechanism ◽  
Antioxidant Enzyme Activities ◽  
Calcium Oxalate Urolithiasis

Gokshuradi Yog (GY)is a polyherbal ayurvedic formulation used traditionally for several decades in India for the treatment of urolithiasis. The aim of the present study was to determine the underlying mechanism ofGYaction in the management of calcium oxalate urolithiasis. The effect ofGokshuradi polyherbal aqueous extracts(GPAEs) was studied on various biochemical parameters involved in calcium oxalate formation by employingin vitroandin vivomethods.GPAEexhibited significant antioxidant activity against 1, 1-diphenyl-2-picrylhydrazyl free radical and inhibited lipid peroxidation in thein vitroexperiments. The rat model of urolithiasis induced by 0.75% ethylene glycol (EG) and 1% ammonium chloride (AC) in water caused polyuria, weight loss, impairment of renal function, and oxidative stress and decreased antioxidant enzyme activities in untreated control groups. However,GPAE-(25, 50, and 100 mg/kg) treated groups caused diuresis accompanied by a saluretic effect and revealed significant increase in antioxidant enzyme activities along with decreased oxalate synthesizing biochemical parameters at higher doses. This study revealed the antiurolithic effect ofGPAEmediated possibly through inhibiting biochemical parameters involved in calcium oxalate formation, along with its diuretic and antioxidant effects, hence supporting its use in the treatment of calcium oxalate urolithiasis.

scholarly journals Zika virus induces oxidative stress and decreases antioxidant enzyme activities in vitro and in vivo

2020 ◽  
Vol 286 ◽  
pp. 198084 ◽  
Author(s):  
Letícia Trindade Almeida ◽  
Ariane Coelho Ferraz ◽  
Camila Carla da Silva Caetano ◽  
Marília Bueno da Silva Menegatto ◽  
Ana Cláudia dos Santos Pereira Andrade ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Enzyme ◽  
Zika Virus ◽  
Enzyme Activities ◽  
Antioxidant Enzyme Activities

scholarly journals In Vitro Effects of Brassinosteroids on the Growth and Antioxidant Enzyme Activities in Groundnut

ISRN Agronomy ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Aman Verma ◽  
C. P. Malik ◽  
V. K. Gupta
Keyword(s):  
Antioxidant Enzyme ◽  
Chlorophyll Content ◽  
Enzyme Activities ◽  
Shoot Multiplication ◽  
Multiple Shoots ◽  
Hill Reaction ◽  
Antioxidant Enzyme Activities ◽  
Mda Content ◽  
In Vitro Effects

This paper deals with the in vitro effects of brassinosteroids (BRs) on growth in the form of multiple shoots, chlorophyll content, Hill reaction activity (HRA), activities of catalase (CAT), peroxidase (POX), polyphenol oxidase (PPX), and ascorbate peroxidase (APX) in Arachis hypogaea L. genotypes (M-13 and PBS24030). In vitro impact of BR on shoot multiplication potential was found to be the best at 1 mL L−1 with BA (3 mg L−1) in both the cultivars. Flowering was observed in PBS24030 on the medium containing 2.0 mL L−1 BR with 3 mg L−1 BA. Rhizogenesis was noticed in the presence of BR alone. Total chlorophyll content and HRA were highest at 2.0 mL L−1 with BA in M-13 and 1.0 mL L−1 with BA in PBS24030. Antioxidant enzyme activities were increased in the presence of BR whether alone or in combination with BA in both the cultivars. However, progressive decline was observed in case of MDA content. The results obtained in the study clearly indicated not only the in vitro establishment of groundnut cultivars in the presence of BR alone and in combination with BA but also its effect on various growth promotory physiological parameters.

In vitro Antiglycation, Antioxidant Properties of Coleus forskohlii ''Balady'' Leaves and Stem and their Antioxidant Enzyme Activities

2017 ◽  
Vol 19 (3) ◽  
pp. 1-11 ◽  
Author(s):  
Yaaser Almulaiky ◽  
Abudukadeer Kuerban ◽  
Faisal Aqlan ◽  
Saeed Alzahrani ◽  
Mohammed Baeshen ◽  
...  
Keyword(s):  
Antioxidant Enzyme ◽  
Enzyme Activities ◽  
Antioxidant Properties ◽  
Antioxidant Enzyme Activities ◽  
Coleus Forskohlii

Growth and Antioxidant Responses in Jatropha curcas Cotyledons under Lead Stress

2009 ◽  
Vol 64 (11-12) ◽  
pp. 859-863 ◽  
Author(s):  
Shun Gao ◽  
Rui Yan ◽  
Jun Wu ◽  
Fu-li Zhang ◽  
Sheng-hua Wang ◽  
...  
Keyword(s):  
Antioxidant Enzyme ◽  
Jatropha Curcas ◽  
Enzyme Activities ◽  
Lead Concentration ◽  
Antioxidant Enzyme Activities ◽  
Sod Activity ◽  
Antioxidant Responses ◽  
Pal Activity

Jatropha curcas embryos were grown in vitro to observe the effects of lead on cotyledon responses. The cotyledon biomass increased initially and then decreased with increasing lead concentration. The SOD activity increased gradually up to 200 μM and then decreased. The POD activity showed a similar trend. The CAT activity was increased at all lead concentrations, the highest activity being observed at 200 μM. However, the PAL activity was inhibited significantly except for 100 μM. Anaylsis by electrophoresis suggested a significant correlation between lead concentration and patterns of SOD, POD and CAT isoenzymes, and these results were consistent with changes of the antioxidant enzyme activities as assayed in solution.

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