scholarly journals Drug Utilization Study in Ophthalmology Outpatients at a Tertiary Care Teaching Hospital

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Pradeep R. Jadhav ◽  
Vijay V. Moghe ◽  
Yeshwant A. Deshmukh

In view of the advancement in drug development and availability of new ocular therapeutics in the discipline of ophthalmology, we attempted to study the drug utilization and describe the prescribing practices of ophthalmologists in a tertiary care teaching hospital. Method. A prospective, cross-sectional, observational study was conducted on patients attending Outpatient Department of Ophthalmology for curative complaints. Prescriptions of 600 patients treated were analyzed by the WHO prescribing indicators and additional indices. Results. Analysis showed that the average number of drugs per prescription was 1.49. Percentage of drugs prescribed by generic name was 2.35%. Percentage of encounters with antibiotics was 44.83%. Percentage of drugs prescribed from National Essential drug list (NEDL)/National Formulary of India (NFI) was 19.48%. Patient's knowledge of correct dosage was 93.83%. Antimicrobial agents were the most commonly prescribed drugs followed by antiallergy drugs and ocular lubricants. Fluoroquinolones accounted for 60% of the total antimicrobial drugs, of which gatifloxacin was the most frequently prescribed fluoroquinolone. Conclusion. The study indicated an awareness of polypharmacy, but showed ample scope for improvement in encouraging the ophthalmologists to prescribe by generic name and selection of essential drugs from NEDL/NFI.

Author(s):  
Sangeetha Raja ◽  
Jamuna Rani R ◽  
Kala P

ABSTRACTObjective: The aim of this study was to carry out adverse drug reactions (ADRs) monitoring in various departments of a tertiary care teaching hospital.Methods: A cross-sectional study was conducted on ADRs reported in the hospital from December 2012 to May 2013 after obtaining InstitutionalEthics Committee approval.Results: A total of 40 ADRs were reported, 47.50% were males and 52.50% were females. The female adult population was 45%. The majority of ADRswere due to antimicrobial agents especially beta-lactam antibiotics (42.5%) followed by NSAIDs (7.50%). A maximum number of patients (75%)were reported with dermatological manifestations. The department of medicine reported the highest number of ADRs (37.5%). As per Naranjo’sprobability scale, 62.5% reports were assessed as probable. 62.5% reports were documented as mild according to Modified Hartwig’s criteria forseverity assessment.Conclusion: This study was done to sensitize the practicing physicians on the importance of adverse drug monitoring and reporting.Keywords: Pharmacovigilance, Adverse drug reactions, Tertiary care teaching hospital, Antimicrobial agents.


Author(s):  
ANCY SEBASTIAN ◽  
ANEESHA PK ◽  
JOSHWA AREECKAL ◽  
SONIYA DAVIS

Objective: The aim of this study is to evaluate the pattern of prescription and utilization of antidepressants (ADs) for various non-psychiatric indications in department of general medicine, cardiology, surgery, gynecology, and orthopaedic of a tertiary care teaching hospital. Methods: A prospective cross-sectional unicentric drug utilization study of inpatients was carried out in a 450 bedded tertiary care hospital. The study included 200 subjects admitted for both psychiatric and non-psychiatric illness. Pediatric patients and those with a length of stay <48 h were excluded from the study. Results: Prescriptions of 200 patients were studied in which 55% were males and 45% were females. The most widely prescribed drug is alprazolam comprising 50% of the total drug consumption and is followed by clonazepam (19.5%), amitriptyline (13.5%), diazepam (9.5%), escitalopram (3.5%), lorazepam (3%), and zolpidem (0.5%). About 36% of the drugs were prescribed in the general medicine department, and 27.5% of the prescriptions were from the cardiology department. Prescriptions from surgery, orthopedics, and gynecology were 16%, 11.5%, and 9% of the total, respectively. Conclusion: ADs were found to be potentially useful for non-psychiatric indications such as peripheral and diabetic neuropathy, gastroenterological conditions, and urological conditions. No benefit was observed in insomnia and musculoskeletal conditions except for fibromyalgia. ADs were also found to improve the treatment outcome and quality of life of patients having comorbid psychiatric conditions being treated for non-psychiatric disorders.


2019 ◽  
Vol 10 (4) ◽  
pp. 55-60
Author(s):  
Saborni Dey ◽  
Vivek Sinha ◽  
Poonam Kachhawa

Background: The drug utilization research is a significant constituent of medical audit which helps in monitoring, evaluating and building required modifications in the prescribing practices to attain a rational and cost effective medical care. Aims and Objective: The objective of this study was to evaluate drug utilization design of Nonsteroidal anti-inflammatory drugs (NSAIDs) in a tertiary care teaching hospital, SIMS, Hapur. Material and Methods: This prospective, observational study was conducted in the outpatients of the Pain clinic during six months period to evaluate the prescribing pattern of analgesics in a tertiary care teaching hospital. After getting approval by Institutional Ethical committee, random prescriptions were collected from the OPD and scanned for the record purpose. The demographic data and the prescription were taken from 340 prescriptions. Data was analyzed as per WHO prescribing indicators. Results: A total 340 prescriptions were analyzed. The result revealed that NSAIDs as Diclofenac (75.21%) and Paracetamol (14.88%) were the most commonly prescribed analgesics. Average number of drugs in the present study was found to be 2.29. Percentage of drugs prescribed generic name was (21.02%). Percentage of encounters with an antibiotic was 12.95%, The use of injectable preparation was around 7.20%. Out of all the medicines, 85.90% were found written from Essential Drug List. Conclusion: The prescribing trend of NSAIDs indicate some deviation from the WHO recommendations. This touchstone data will be useful to plan more targeted research and to improve prescribing practices. These types of studies help to design policy for rational use of drugs and perioding training programs of physicians, establishing drug and therapeutic committee, drug information centres and regular educational interventions that can be beneficial for improving prescribing practice with rational drug usage.


Author(s):  
Sunil Kardani ◽  
Rajesh Hadia ◽  
Jay Patel ◽  
Jeel Patel ◽  
Trupal Rathod ◽  
...  

Background: Antiepileptic drugs (AEDs) are the mainstay of the therapy for epilepsy, despite the development in recent years of new therapeutic options, such as brain stimulation or Surgery. Objective: To understand the pattern of drug utilization and medication adherence of anti-epileptic drugs (AEDs) among epileptic patients at a tertiary care teaching hospital. Methodology: A cross-sectional observational study of a total of 120 subjects receiving anti-epileptics was done. All the patients with epilepsy were prescribed with anti-epileptic drug who visited, admitted, or referred to the Department of Neurology. All inpatients and outpatients of epilepsy were screened for the study. Results: A total of 120 patients were included in our study into which (38.33%) were inpatients and (61.67%) were outpatient. The male (56%) patients were more as compared to female (44%) patients. A maximum number of patients were from the age group of 21-40 (41%) year. The majority of the patient were suffered from focal epilepsy (63%), remaining were having a generalized seizure. The highest comorbidities were found to be HTN and diabetes mellitus. Monotherapy was highly prescribed as compare to polytherapy. Among single AED, the maximum prescribed drug was Carbamazepine [30% (N=17)] followed by 25% (N=14) of phenytoin and levetiracetam 21% (N=12). In two AED Combinations, the most prescribed drugs were clobazam + Levetiracetam and Midazolam + phenytoin 12% (N=5) followed by sodium valproate + clobazam 10% (N=4). Highest combination of three AEDs that were prescribed the highest were carbamazepine + Levetiracetam + clobazam and phenytoin + phenobarbitone + sodium Valproate 20% (N=2) The highest medication adherence was found in patients who were on single AEDs and the lowest adherence was found in the patients who were on more than two AEDs. Conclusion: Antiepileptic drug monotherapy was highly prescribed as compare to polytherapy. Phenytoin was the most commonly prescribed AEDs followed by carbamazepine and highly prescribed single AEDs were found to be carbamazepine. The patients who were on single epileptic drugs showed the highest adherence as compared to the patients with more than two AEDs.


2020 ◽  
pp. 1-3
Author(s):  
Luna Kuli ◽  
Nilotpal Barua

Introduction: The importance of conducting drug utilization pattern studies is to study the prescribing trends to promote rational prescribing & develop awareness amongst prescribers. Aim and Objectives: To evaluate the current prescribing and drug utilization pattern in the treatment of ocular allergies in a tertiary care teaching hospital of Assam. Materials and Methods: A total of 265 prescriptions were assessed. A retrospective study was conducted at the Department of Ophthalmology and Pharmacology, Assam Medical College and Hospital, Dibrugarh, Assam for a period of 2 months from 1/01/2018 to 28/02/2018. Patients of either sex and all ages were included. Patients with concomitant diseases like diabetes, hypertension or other diseases were excluded. Results: The commonest ocular allergy was simple allergic conjunctivitis. The male: female ratio was 1.95. Commonest age group affected by the disease is 31-40 years. The average number of drugs per prescription was 1.68. Olopatadine was the most commonly prescribed drug. Topical route was the commonest. The demographic details of the patient such as name, age, sex, address, chief complaints, findings, diagnosis, Rx symbol, doctor’s signature were present in all prescriptions. Conclusion: No polypharmacy or irrational drug use were noticed.


2021 ◽  
pp. 77-78
Author(s):  
Sakshi Singh ◽  
Pushpawati Jain ◽  
Shipra Jain

The present study was conducted with the aim to evaluate the drug utilization pattern among geriatric patients of a tertiary care teaching hospital. A cross sectional study was conducted on elderly patients admitted in departments of Medicine and Surgery in a tertiary care teaching hospital. All the prescriptions were evaluated using WHO prescribing indicators. Total 200 prescriptions were collected during the study period. Most of the patients were in the age group of 65-69 years (68.5%) with male preponderance. Surgical conditions were the most common cause requiring hospitalization. Total 2045 drugs were prescribed to study participants with average number of drugs per prescription as 10.23 ± 3.14. Generic prescribing constituted 59.8% while antibiotics were prescribed in 15.5% of prescriptions. The total number of injections prescribed was 41.7% and drugs prescribed from WHO-EML constituted 41.5%. The present study highlights the signicance of drug utilization studies in geriatric


2021 ◽  
Vol 12 (6) ◽  
pp. 65-69
Author(s):  
Kranti Tekulapally

Background: Rational use of drugs significantly impacts the treatment outcomes and the cost of health care. Most of the medical students are exposed to rational use of medicines and prescription writing during their second year but it is only during internship that they actually start prescribing under expert guidance. Aims and Objective: This study was planned to assess the rational prescribing practices of Interns in a tertiary care teaching hospital. Materials and Methods: With prior approval from Institutional Ethics Committee, a cross sectional study was conducted among 2014 batch of Interns from Malla Reddy Medical College for Women, Suraram, Hyderabad. Hard copies of prevalidated questionnaire consisting of 23 questions including a question on writing a prescription for a patient suffering from cold and fever was administered to the students after taking oral informed consent. Data from completed questionnaires was entered into excel sheet and analysed using descriptive statistics. Results: Of 64 interns, only 20% were aware of the term rational use of medicines, 75% of the term essential medicines and 22% of p drugs. Most of them were unaware of the step criteria for p drugs and advantages of using p drugs (87%). 95% of them reiterated that they could label the parts of prescription but mean score of the interns for writing a prescription was 3. 62% of them had positive attitude towards prescription writing. Conclusion: There is a need to improve the knowledge, attitude and practices of Rational use of Medicinesamong the Interns. Educational interventional strategies in the form of seminars, workshops, orientation programs can be adopted to promote rational use of medicines.


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