scholarly journals Adderall Induced Acute Liver Injury: A Rare Case and Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Rohini R. Vanga ◽  
Bikram Bal ◽  
Kevin W. Olden
Keyword(s):  
Liver Injury ◽  
Rare Case ◽  
Acute Liver Injury ◽  
Past History ◽  
English Literature ◽  
Review Of The Literature ◽  
Intensive Monitoring ◽  
Hyperactivity Disorder ◽  
History Of ◽  
Time Of Presentation

Adderall (dextroamphetamine/amphetamine) is a widely prescribed medicine for the treatment of attention-deficit/hyperactivity disorder (ADHD) and is considered safe with due precautions. Use of prescribed Adderall without intention to overdose as a cause of acute liver injury is extremely rare, and to our knowledge no cases have been reported in the English literature. Amphetamine is an ingredient of recreational drugs such as Ecstacy and is known to cause hepatotoxicity. We describe here the case of a 55-year-old woman who developed acute liver failure during the treatment of ADHD with Adderall. She presented to the emergency room with worsening abdominal pain, malaise, and jaundice requiring hospitalization. She had a past history of partial hepatic resection secondary to metastasis from colon cancer which was under remission at the time of presentation. She recovered after intensive monitoring and conservative management. Adderall should be used carefully in individuals with underlying liver conditions.

scholarly journals Renal Metastases of a Femur Osteosarcoma: A Case Report and a Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Yousra Akasbi ◽  
Samia Arifi ◽  
Karim Lahlaidi ◽  
Tarik Namad ◽  
Nawfel Mellas ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Case ◽  
English Literature ◽  
Renal Involvement ◽  
Review Of The Literature ◽  
Metastatic Osteosarcoma ◽  
History Of ◽  
Renal Metastases

This paper discusses a rare case of renal metastatic osteosarcoma. A 25-year-old man with a history of metastatic osteosarcoma involving his right kidney was referred to our institution for treatment. He was managed with chemotherapy. An exhaustive review of the English literature pertaining to this disease was performed. To our knowledge, this case represents only the sixteenth. The literature suggests that the incidence of renal involvement in osteosarcoma is significant and that the treatment should be multidisciplinary in such patients.

Primary B-cell lymphoma presenting as bilateral ear lobule swelling

2007 ◽  
Vol 121 (12) ◽  
pp. 1207-1209 ◽  
Author(s):  
A K Sharma ◽  
S Chatterjee ◽  
V L Sharma
Keyword(s):  
B Cell ◽  
Rare Case ◽  
Cell Lymphoma ◽  
English Literature ◽  
B Cell Lymphoma ◽  
Excision Biopsy ◽  
History Of ◽  
One Year

AbstractWe report a rare case of primary B-cell lymphoma presenting as bilateral ear lobule swelling. A 56-year-old white man presented with a one-year history of painless swelling of both ear lobules. An excision biopsy confirmed B-cell lymphoma. Detailed systemic investigation confirmed the primary nature of the tumour. This tumour is rare in the ear lobule. A review of the English literature revealed no previously reported case of bilateral primary ear lobule involvement. Clinicians should be aware that this tumour can present as a primary in the ear lobules.

scholarly journals IgG4-Related Hashimoto's Thyroiditis of the Thyroid Gland

2017 ◽  
Vol 102 (5-6) ◽  
pp. 222-226
Author(s):  
Sang Yull Kang ◽  
Yo Na Kim ◽  
Seon Kwang Kim ◽  
Hyun Jo Youn ◽  
Sung Hoo Jung
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Rare Case ◽  
Thyroid Dysfunction ◽  
Past History ◽  
Hashimoto's Thyroiditis ◽  
Neck Swelling ◽  
Comprehensive Understanding ◽  
Anterior Neck ◽  
History Of ◽  
Proper Diagnosis

Immunoglobulin (Ig) G4-related Hashimoto's thyroiditis is a newly discovered subtype of Hashimoto's thyroiditis and characterized by thyroid inflammation and marked fibrosis. IgG4-related Hashimoto's thyroiditis is very rare and there has been relatively little information available to date. A 46-year-old woman with a past history of thyroid dysfunction visited our outpatient clinic for severe anterior neck swelling. She complained of swallowing discomfort and pain due to severe goiter and was successfully treated with total thyroidectomy. Immunohistochemistry showed thyroid invasion by IgG4-positive cells and an IgG4/IgG ratio over 40%. The patient was diagnosed with IgG4-related Hashimoto's thyroiditis. We report a very rare case of IgG4-related Hashimoto's thyroiditis with severe goiter. A more comprehensive understanding of the IgG4-related Hashimoto's thyroiditis may help physicians to allow proper diagnosis and treatment of patients with severe goiter.

Schwannoma of the Greater Superficial Petrosal Nerve: An Unusual Site for a Common Tumor

2020 ◽  
Vol 81 (06) ◽  
pp. 565-570
Author(s):  
Alok Mohan Uppar ◽  
Shilpa Rao ◽  
Chandrajit Prasad ◽  
Arivazhagan Arimappamagan ◽  
Vani Santosh
Keyword(s):  
Facial Nerve ◽  
Rare Case ◽  
Literature Search ◽  
English Literature ◽  
Clinical Spectrum ◽  
Small Subset ◽  
Rare Clinical Entity ◽  
Review Of The Literature ◽  
Unusual Site ◽  
Greater Superficial Petrosal Nerve

AbstractGreater superficial petrosal nerve (GSPN) schwannoma is a rare clinical entity. It forms a small subset of the larger group of facial nerve schwannomas. A thorough literature search yielded only 27 such cases reported to date in the English literature. We present one such rare case of GSPN schwannoma and discuss the clinical spectrum and management along with a review of the literature. We demonstrate the surgical steps in an operative video.

Salivary gland pathology in the paediatric population: implications for management and presentation of a rare case

2014 ◽  
Vol 128 (1) ◽  
pp. 104-106 ◽  
Author(s):  
L Jablenska ◽  
A Trinidade ◽  
V Meranagri ◽  
P Kothari
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Rare Case ◽  
Paediatric Population ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Superficial Parotidectomy ◽  
History Of ◽  
Painless Mass ◽  
Salivary Gland Pathology

AbstractIntroduction:Salivary gland pathology in the paediatric population is rare and can present management challenges regarding both investigation and treatment.Method:Case report and review of available literature.Results:A seven-year-old, fit, well girl presented with a two-month history of a painless mass over the left parotid area. Ultrasonography confirmed the presence of a well-defined, 1.5 × 2 cm, predominantly solid lesion with minor internal cystic spaces arising from the superficial part of the gland. Magnetic resonance imaging showed no invasion of the deep lobe or skeletal erosion. Superficial parotidectomy was performed via a facelift incision. Histopathology confirmed a diagnosis of pleomorphic adenoma. Review of the literature emphasised important differences in managing this pathology in the paediatric population when compared with adults.Conclusion:We present the youngest reported case of a pleomorphic adenoma of the parotid gland, detail its management, and discuss the general approach to parotid pathology management in the paediatric population.

A Rare Case of Chorea Gravidarum

2010 ◽  
Vol 2 (2) ◽  
pp. 145-146 ◽  
Author(s):  
Madhuri Gawande ◽  
Sunita Ghike ◽  
Sheela Jain
Keyword(s):  
Rheumatic Fever ◽  
Rare Case ◽  
Past History ◽  
Factors Associated ◽  
Sydenham’S Chorea ◽  
Generic Term ◽  
History Of ◽  
Sydenham's Chorea ◽  
Childhood Factors

ABSTRACT Chorea Gravidarum is the term given to chorea occurring during pregnancy. It is not an etiologically or pathologically distinct morbid entity but generic term for chorea of any etiology. We report a case of Chorea Gravidarum, who had past history of Rheumatic fever and Sydenham's Chorea in childhood. Factors associated with recurrence of chorea; those aggravating chorea during pregnancy and its management have been discussed.

A Rare Case of Sulfasalazine-Induced DRESS Syndrome With Acute Liver Injury

2017 ◽  
Vol 112 ◽  
pp. S1255-S1256
Author(s):  
Amit Mehta ◽  
Vikas Gupta ◽  
Luke Olson ◽  
Sonal Kumar ◽  
David Wan
Keyword(s):  
Liver Injury ◽  
Rare Case ◽  
Acute Liver Injury ◽  
Dress Syndrome

scholarly journals Bicalutamide-Associated Acute Liver Injury and Migratory Arthralgia: A Rare but Clinically Important Adverse Effect

2018 ◽  
Vol 12 (2) ◽  
pp. 266-270 ◽  
Author(s):  
Helga M. Gretarsdottir ◽  
Elin Bjornsdottir ◽  
Einar S. Bjornsson
Keyword(s):  
Prostate Cancer ◽  
Liver Injury ◽  
Causality Assessment ◽  
Acute Liver Injury ◽  
Assessment Method ◽  
Hepatitis Viruses ◽  
Drug Induced ◽  
History Of ◽  
Upper Abdomen ◽  
Liver Tests

We describe a case of acute liver injury and migratory arthralgia in a patient receiving bicalutamide treatment for prostate cancer. A 67-year-old male with metastatic prostate cancer presented with a 6-day history of migratory arthralgia. He had been undergoing treatment with bicalutamide for 4 months; 3 weeks prior to symptom appearance the bicalutamide dose had been increased. He had no other symptoms. Liver tests and inflammatory markers were markedly elevated. Serology for hepatitis viruses A, B, and C, CMV, and EBV and autoimmune causes were all negative, and an ultrasound of the upper abdomen was normal. There was no history of blood transfusion, intravenous drug abuse, or alcohol abuse. Due to the suspicion of a drug-induced symptomatology, bicalutamide was discontinued and the patient started on 30 mg prednisolone daily. Three weeks later he was symptom free and after 6 weeks his liver tests were almost normal. The Roussel Uclaf Causality Assessment Method (RUCAM) suggested a high probability of liver injury. Bicalutamide has very rarely been reported as a causative agent for liver injury and to our knowledge never for migratory polyarthralgia. The migratory polyarthralgia was attributed to bicalutamide due to the absence of other etiological factors and the disappearance of symptoms after discontinuation of the drug. To our knowledge, this is the first published case report of migratory arthralgia and concomitant liver injury attributed to bicalutamide.

scholarly journals A Rare Adrenal Mass in a 3-Month-Old: A Case Report and Literature Review

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Ashish Garg ◽  
Elza Pollak-Christian ◽  
Navneetha Unnikrishnan
Keyword(s):  
Adrenal Mass ◽  
Rare Case ◽  
Adrenal Tumor ◽  
Case Reports ◽  
English Literature ◽  
Abdominal Ultrasound ◽  
Cell Tumor ◽  
Review Of The Literature ◽  
Pediatric Case ◽  
Palpable Mass

A three-month-old female infant presented with abdominal distention for 2 months. A large palpable mass in right upper quadrant was noted on physical exam. Abdominal ultrasound revealed a large heterogeneous mass with multiple cystic components. Mass was surgically excised and pathology was consistent with mature adrenal teratoma. Teratoma is a germ cell tumor mainly found in gonadal tissues. Occurrence of adrenal gland teratoma in children is very rare with less than 10 pediatric case reports in English literature. We present a rare case of primary adrenal tumor in an infant and a review of the literature.

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