scholarly journals Correlation between Density and Resorption of Fresh-Frozen and Autogenous Bone Grafts

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Simone Lumetti ◽  
Carlo Galli ◽  
Edoardo Manfredi ◽  
Ugo Consolo ◽  
Claudio Marchetti ◽  
...  

Trial Design. This analysis compared the outcome of fresh-frozen versus autologous bone block grafts for horizontal ridge augmentation in patients with Cawood and Howell class IV atrophies.Methods. Seventeen patients received autologous grafts and 21 patients received fresh-frozen bone grafts. Patients underwent CT scans 1 week and 6 months after surgery for graft volume and density analysis.Results. Two autologous and 3 fresh-frozen grafts failed. Autologous and fresh-frozen grafts lost, respectively, 28% and 46% of their initial volume(P=0.028). It is noteworthy that less dense fresh-frozen blocks lost more volume than denser grafts (61% versus 16%).Conclusions. According to these 6-month results, only denser fresh-frozen bone graft may be an acceptable alternative to autologous bone for horizontal ridge augmentation. Further studies are needed to investigate its behaviour at longer time points.

2018 ◽  
Vol 29 (4) ◽  
pp. 325-334 ◽  
Author(s):  
Julio Leonardo de Oliveira Lima ◽  
Daniel Isaac Sendyk ◽  
Wilson Roberto Sendyk ◽  
Cristiane Ibanhes Polo ◽  
Luciana Correa ◽  
...  

Abstract Several techniques have been proposed for vertical bone regeneration, and many of them use bone autogenous and allogeneic grafts. The purpose of this study was to compare demineralised freeze-dried bone allografts (DFDBA), fresh-frozen (FF) allografts, autogenous bone grafts to find differences between volumetric and histological quantity of bone formation and vertical bone growth dynamic. A vertical tissue regeneration bone model was performed in rabbit calvarias under general anaesthesia. Four hollow cylinders of pure titanium were screwed onto external cortical bone calvarias in eight rabbits. Each one of the cylinders was randomly filled with one intervention: DFDBA, FF, autogenous bone, or left to be filled with blood clot (BC) as control. Allogeneic grafts were obtained from a ninth animal following international standardised protocols for the harvesting, processing, and cryopreservation of allografts. Autogenous graft was obtained from the host femur scraping before adapting hollow cylinders. Animals were euthanized at 13 weeks. Vertical volume was calculated after probe device measurements of the new formed tissue inside the cylinders and after titanium cylinders were removed. Histomorphometry and fluorochrome staining were used to analyse quantity and dynamic of bone formation, respectively. Results showed that DFDBA and fresh-frozen bone improved the velocity and the quantity of bone deposition in distant portions of the basal plane of grafting. Remaining material in allograft groups was more intense than in autogenous group. Both allografts can be indicated as reliable alternatives for volume gain and vertical bone augmentation.


2011 ◽  
Vol 37 (2) ◽  
pp. 223-231 ◽  
Author(s):  
Cintia Mussi Milani Contar ◽  
João Rodrigo Sarot ◽  
Maite Barroso da Costa ◽  
Jayme Bordini ◽  
Antonio Adilson Soares de Lima ◽  
...  

Abstract Bone allograft has become an alternative to autogenous bone due to its decreased operative trauma and the almost unlimited supply of reconstructive material. The aim of the present study was to histologically evaluate the suitability of fresh-frozen bone graft (test group) used in maxillary ridge augmentation, comparing it to autogenous bone (native maxilla: control group). During the re-entry procedures, 9 months after the fresh-frozen allogeneic bone blocks were placed in the atrophic maxillary ridges, bone cores were removed with a trephine bur from test and control treatments in the same patient. Routine histologic processing using hematoxylin and eosin and Picrosirius staining was performed. Mature and immature collagen area and density analysis were carried out for both groups under polarization. The results of Student’s t test for paired samples (P > .05) showed no statistically significant difference in mature and immature collagen area or density percentage between test and control groups. Histologically similar bone formation patterns were observed in both groups. We concluded that fresh-frozen bone allograft is a biologically acceptable alternative for augmentation of the deficient alveolar ridge, showing a similar collagen pattern to that of autogenous bone.


2004 ◽  
Vol 15 (1) ◽  
pp. 73-81 ◽  
Author(s):  
Mario Roccuzzo ◽  
Guglielmo Ramieri ◽  
Mario Cristina Spada ◽  
Silvio Diego Bianchi ◽  
Sid Berrone

2011 ◽  
Vol 15 (2) ◽  
pp. 262-270 ◽  
Author(s):  
Rubens Spin Neto ◽  
Coletti Felipe Leite ◽  
Luis Antonio Violin Dias Pereira ◽  
Elcio Marcantonio ◽  
Elcio Marcantonio Jr

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