Utilization of the phyphox application (physical phone experiment) to calculate the moment of inertia of hollow cylinders

Experiments have been carried out on determining the value of the moment of inertia of a hollow cylinder. This study aims to analyze the value of the moment of inertia with variations in the radius of the hollow cylinder using the Phyphox Application (Physical Phone Experiment). This research is experimental. The tools and material used area 1-meter longboard, three hollow cylinders with different radius sizes but the same mass, smartphone, laptop, caliper, and balance.The experiment of rolling motion on a hollow cylinder on an inclined plane is assisted by data processing in a Phyphoxapplication. From the experiment, the result of the moment of inertia value from data processing is 4.89 x 10-4kg.m2, 9.82 x 10-4kg.m2, 12.4 x10-4kg.m2. This research can be used as a teacher reference in teaching the topic of moments of inertia in physics learning at school. This is highly recommended for distance learning during the pandemic so that mastery of concepts is maximized. Further research is suggested that it can be tried to use other materials with other types of rigid bodies to find the moment of inertia. Further references on digital application media to assist learning are also needed considering the dynamic development of technology.

αTAT1-induced tubulin acetylation promotes ameloblastoma migration and invasion

Ameloblastoma (AB) is the most common benign epithelial odontogenic tumor occurring in the jawbone. AB is a slowly growing tumor but sometimes shows a locally invasive and an aggressive growth pattern with a marked bone resorption. In addition, the local recurrence and distant metastasis of AB also sometimes occurs, which resembles one of the typical malignant potentials. From these points of view, to understand better the mechanisms of AB cell migration or invasion is necessary for the better clinical therapy and improvements of the patients’ quality of life. Microtubules in eukaryotic cells reveal the shape of hollow cylinders made up of polymerized alpha (α)- and beta (β)-tubulin dimers and form the cytoskeleton together with microfilaments and intermediate filaments. Microtubules play important roles in cell migration by undergoing assembly and disassembly with post-translational modifications. Stability of microtubules caused by their acetylation is involved in cell migration. In this study, we investigated the expression and distribution of acetylated α-tubulin and alpha-tubulin N-acetyltransferase 1 (αTAT1), an enzyme which acetylates Lys-40 in α-tubulin, in AB specimens, and analyzed how tubulin was acetylated by αTAT1 activation in a human AB cell line, AM-1. Finally, we clarified that TGF-β-activated kinase1 (TAK1) was phosphorylated by TGF-β stimulation, then, induced tubulin acetylation via αTAT1 activation, which subsequently activated the migration and invasion of AB cells.

Modeling a Free Burnishing of a Powder Hollow Cylinder

The paper presents the results of the computer modelling of the stressed state and relative density when burnishing a porous hollow cylinder, made from copper sintered powder material. The mathematical model, based on the theory of porous bodies’ plasticity, is used for the analysis. The paper researches the impact of the initial porosity of the material on the effective stresses distribution, relative density and force change when free burnishing of hollow cylinders. It is ascertained that with the decrease of the initial porosity of the sintered material there is the increase of the burnishing force, stresses rate and relative density on the inner sur-face of a hollow cylinder. For porous materials at a certain stage of burnishing, the deformation zone is transformed into the compaction zone with a high relative density which de-creases while moving away from the inner surface of hollow cylinders. The maximum value of the relative density is implemented directly on the inner surface of hollow cylinders; along with this the density value is evenly distributed on the inner wall.

Boiling Heat Transfer Characteristics of Rotary Hollow Cylinders with In-Line and Staggered Multiple Arrays of Water Jets

Transient heat transfer studies of quenching rotary hollow cylinders with in-line and staggered multiple arrays of jets have been carried out experimentally. The study involves three hollow cylinders (Do/d = 12 to 24) with rotation speed 10 to 50 rpm, quenched by subcooled water jets (ΔTsub=50-80 K) with jet flow rate 2.7 to 10.9 L/min. The increase in area-averaged and maximum heat flux over quenching surface (Af) has been observed in the studied multiple arrays with constant Qtotal compared to previous studies. Investigation of radial temperature distribution at stagnation point of jet reveals that the footprint of configuration of 4-row array is highlighted in radial distances near the outer surface and vanishes further down toward the inner surface. The influence of the main quenching parameters on local average surface heat flux at stagnation point is addressed in all the boiling regimes where the result indicates jet flow rate provides strongest effect in all the boiling regimes. Effectiveness of magnitude of maximum heat flux in the boiling curve for the studied parameters is reported. The result of spatial and temporal heat flux by radial conduction in the solid presents projection depth of cyclic variation of surface heat flux in the radial axis as it disappears near inner surface of hollow cylinder. In addition, correlations are proposed for area-averaged Nusselt number as well as average and maximum local heat flux at stagnation point of jet for the in-line and staggered multiple arrays.

Crack Propagation Calculation for Axial Cracks in Hollow Cylinders Subjected to Thermal Shock

The core region of the RPV can be considered a hollow circular cylinder disregarding the geometrical details due to nozzles. This contribution investigates the prediction capabilities for crack initiation, crack growth and arrest by means of a rather simple method based on the closed-weight function formula for the stress intensity factor (SIF) for axial cracks in hollow cylinders subjected to thermal shock. The method is explained together with some illustrative examples for real low allow steel used in nuclear applications. In order to obtain the temperature and stress distribution in the cylinder during the thermal shock, a finite element (FE) model is defined to obtain the uncoupled solution of these two fields needed for the closed-weight function. Since the material exhibits a ductile-brittle transition fracture behavior, the temperature-dependent fracture toughness for initiation and for arrest are described using the ASME model. The solution for the SIF is based on linear elastic fracture mechanics (LEFM) and therefore only elastic material is assumed and the crack can propagate in brittle manner. The crack initiates propagation if the SIF value at the crack tip reaches the fracture toughness (for initiation) and propagates unstably in mode I unless the fracture arrest toughness is reached. The quality of the solution is checked by comparing the obtained solution for a “stationary” crack with the calculated extended finite element method (XFEM) solution for the same loading transient. The results show that for some geometries of the cylinder, the crack stops and in some other cases the crack propagates until the cylinder fails. The combined closed-weight function-initiation-growth-arrest (WFF-IGA) algorithm does not require expensive computational resources and gives fast reliable results. The WFF-IGA method provides a powerful and economical way to predict the crack propagation and arrest of the initial crack. This is an advantage when an optimization of the structure is needed.