scholarly journals Superior Mesenteric Artery Syndrome in a Patient with Cerebral Palsy

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Adi Neuman ◽  
Bhavita Desai ◽  
Daniel Glass ◽  
Wassim Diab
Keyword(s):  
Weight Loss ◽  
Cerebral Palsy ◽  
Abdominal Pain ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
High Index ◽  
Superior Mesenteric Artery Syndrome ◽  
The Third ◽  
Abdominal Symptoms ◽  
High Index Of Suspicion

Superior mesenteric artery syndrome involves compression of the third part of the duodenum due to narrowing of the area between the aorta and the superior mesenteric artery (SMA). We will describe the case of a 34-year-old with cerebral palsy who presented with abdominal pain, nausea, vomiting, and weight loss and was diagnosed with SMA syndrome via CT-imaging. With failure of conservative measures, our patient underwent a duodenojejunostomy after which improvement in her weight as well as relief of her abdominal symptoms was noted. Given the rarity of this syndrome, physicians need to keep a high index of suspicion in order to prevent the damaging consequences.

An uncommon cause of abdominal pain and weight loss: the superior mesenteric artery syndrome

VASA ◽  
2014 ◽  
Vol 43 (2) ◽  
pp. 149-153 ◽  
Author(s):  
Yasemin Gunduz ◽  
Fatih Altintoprak ◽  
Kiyasettin Asil ◽  
Guner Cakmak
Keyword(s):  
Weight Loss ◽  
Abdominal Pain ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Superior Mesenteric Artery Syndrome

scholarly journals Superior mesenteric artery syndrome: a single centre experience of laparoscopic duodenojejunostomy as the operation of choice

2017 ◽  
Vol 99 (6) ◽  
pp. 472-475 ◽  
Author(s):  
GC Kirby ◽  
ER Faulconer ◽  
SJ Robinson ◽  
A Perry ◽  
R Downing
Keyword(s):  
Weight Loss ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Epigastric Pain ◽  
Superior Mesenteric Artery Syndrome ◽  
Team Approach ◽  
The Third ◽  
Wilkie’S Syndrome ◽  
Sma Syndrome ◽  
Open Gastrojejunostomy

INTRODUCTION The superior mesenteric artery (SMA) syndrome, or Wilkie’s syndrome, is a rare cause of postprandial epigastric pain, vomiting and weight loss caused by compression of the third part of the duodenum as it passes beneath the proximal superior mesenteric artery. The syndrome may be precipitated by sudden weight loss secondary to other pathologies, such as trauma, malignancy or eating disorders. Diagnosis is confirmed by angiography, which reveals a reduced aorto-SMA angle and distance, and contrast studies showing duodenal obstruction. Conservative management aims to increase intra-abdominal fat by dietary manipulation and thereby increase the angle between the SMA and aorta. Where surgery is indicated, division of the ligament of Treitz, anterior transposition of the third part of the duodenum and duodenojejunostomy have been described. METHODS We present four cases of SMA syndrome where the intention of treatment was laparoscopic duodenojejunostomy. The procedure was completed successfully in three patients, who recovered quickly with no short-term complications. A fourth patient underwent open gastrojejunostomy (complicated by an anastomotic bleed) when dense adhesions prevented duodenojejunostomy. CONCLUSIONS The superior mesenteric artery syndrome should be considered in patients with epigastric pain, prolonged vomiting and weight loss. Laparoscopic duodenojejunostomy is a safe and effective operation for management of the syndrome. A multi-speciality team approach including gastrointestinal, vascular and radiological specialists should be invoked in the management of these patients.

scholarly journals Superior Mesenteric Artery Syndrome Associated with Rapid Weight Loss Attributed to Amphetamine Abuse

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Richard M. Fazio ◽  
On Chen ◽  
Wael Eldarawy
Keyword(s):  
Weight Loss ◽  
Abdominal Pain ◽  
Superior Mesenteric Artery ◽  
Female Patient ◽  
Mesenteric Artery ◽  
Rapid Weight Loss ◽  
Amphetamine Abuse ◽  
The Third ◽  
Sma Syndrome ◽  
Number Of Factors

Superior mesenteric artery (SMA) syndrome arises from a reduction in the angle formed between the SMA and the aorta, thereby compressing the third portion of the duodenum. This phenomenon may be caused by a number of factors, one of which being acute weight loss. We report a case of a female patient presenting with abdominal pain and vomiting who developed superior mesenteric artery (SMA) syndrome as a result of rapid weight loss, thought to be secondary to amphetamine abuse. This association can often be overlooked and, to our knowledge, has not been previously reported.

scholarly journals Wilkie’s Syndrome Following Weight Loss in a Trauma Patient

2020 ◽  
pp. 1-3
Author(s):  
George Oosthuizen ◽  
George Oosthuizen
Keyword(s):  
Weight Loss ◽  
Trauma Patient ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Treatment Options ◽  
Rare Condition ◽  
Feeding Tube ◽  
Significant Weight Loss ◽  
The Third ◽  
Wilkie’S Syndrome

Wilkie’s syndrome, or superior mesenteric artery syndrome, is a rare condition of duodenal obstruction caused by compression of the superior mesenteric artery on the third part of the duodenum. The diagnosis should be considered in a patient who has experienced significant weight loss and now presents with persistent vomiting, especially if the vomiting occurs with the patient in the supine position and is alleviated by the lateral or prone position. The diagnosis can be confirmed by imaging studies demonstrating compression of the third part of the duodenum, and the main aim of treatment should be to pass a feeding tube beyond the point of obstruction to allow enteral feeding. The condition improves spontaneously with weight gain. Further treatment options include parenteral feeding and operative bypass in select cases. Here we present a case of Wilkie’s syndrome in a trauma patient with significant weight loss, together with a review of the literature on this interesting topic.

scholarly journals Mitochondrial disease: an uncommon but important cause of diabetes mellitus

2018 ◽  
Vol 2018 ◽  
Author(s):  
Ming Li Yee ◽  
Rosemary Wong ◽  
Mineesh Datta ◽  
Timothy Nicholas Fazio ◽  
Mina Mohammad Ebrahim ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Weight Loss ◽  
Lactic Acidosis ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Mitochondrial Disorder ◽  
Superior Mesenteric Artery Syndrome ◽  
List Type ◽  
Presenting Symptoms ◽  
History Of

Summary Mitochondrial diseases are rare, heterogeneous conditions affecting organs dependent on high aerobic metabolism. Presenting symptoms and signs vary depending on the mutation and mutant protein load. Diabetes mellitus is the most common endocrinopathy, and recognition of these patients is important due to its impact on management and screening of family members. In particular, glycemic management differs in these patients: the use of metformin is avoided because of the risk of lactic acidosis. We describe a patient who presented with gradual weight loss and an acute presentation of hyperglycemia complicated by the superior mesenteric artery syndrome. His maternal history of diabetes and deafness and a personal history of hearing impairment led to the diagnosis of a mitochondrial disorder. Learning points: The constellation of diabetes, multi-organ involvement and maternal inheritance should prompt consideration of a mitochondrial disorder. Mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes (MELAS) and maternally inherited diabetes and deafness (MIDD) are the most common mitochondrial diabetes disorders caused by a mutation in m.3243A>G in 80% of cases. Metformin should be avoided due to the risk of lactic acidosis. There is more rapid progression to insulin therapy and higher prevalence of diabetic complications compared to type 2 diabetes. Diagnosis of a mitochondrial disorder leads to family screening, education and surveillance for future complications. Superior mesenteric artery syndrome, an uncommon but important cause of intestinal pseudo-obstruction in cases of significant weight loss, has been reported in MELAS patients.

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