scholarly journals Multiple Congenital Epulis in Alveolar Ridges of Maxilla and Mandible in a Newborn: A Rare Case Report

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Nader Saki ◽  
Somayeh Araghi
Keyword(s):  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Respiratory Problems ◽  
Pathologic Features ◽  
Rare Case Report ◽  
Oral Cavity Tumor ◽  
Single Mass ◽  
Congenital Epulis ◽  
Maxilla And Mandible

Congenital granular cell lesion (CGCL) or congenital epulis is an uncommon benign of the oral cavity tumor appearing at birth with typical clinical and pathologic features. It predominately affects females, mainly on the anterior maxillary alveolar ridge, and occurs usually as a single mass, although sometimes as multiple. The left side incisor area is the most common site. The etiology and histogenesis of the lesion remain obscure. Though it is a benign lesion, the tumor may cause feeding and respiratory problems if there are too large or multiple tumors. We report a case of a three-day-old, female newborn, who was referred to our hospital with multiple congenital oral swellings arising from the maxilla and mandible. The tumors caused a feeding problem and, hence, they were resected by surgical excision under general anesthesia.

scholarly journals 999 Case Report: A Rare Congenital Granular Cell Epulis In a Newborn Female Infant

2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
R O'Rorke ◽  
D Ramkumar ◽  
S Jones
Keyword(s):  
Case Report ◽  
Early Diagnosis ◽  
Infant Feeding ◽  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Excisional Biopsy ◽  
Histopathological Analysis ◽  
Anterior Maxilla ◽  
Congenital Granular Cell Epulis

Abstract Background A congenital granular cell epulis (CGCE) is a rare benign lesion of uncertain histologic origin that is found on the mucosa of the alveolar ridges of newborn babies. There have been less than 250 reported cases of CGCE. They are most commonly found in the anterior maxilla region in female infants. Case Report An 8-week-old female was referred from the Neonatal team with a 10mmX5mm lesion found at birth on the mucosa of the anterior maxilla. She was seen in the Oral and Maxillofacial Department where her parents reported that the lesion was causing discomfort when feeding and they were keen for its removal. On initial medical examination the patient was diagnosed with a Grade 1 ejection systolic murmur and was awaiting further cardiac investigations. With this in mind and the young age of the patient, it was decided an excisional biopsy of the lesion under local anaesthesia (LA) would be the safest option. The lesion was excised uneventfully when the patient was 9 weeks old. It was shown to be a congenital granular cell epulis following histopathological analysis. The patient was reviewed 8 weeks post-operatively. There were no signs of recurrence, the infant’s feeding had improved drastically, and she was thriving. Discussion CGCE is a rare and interesting lesion in neonates. Early diagnosis and treatment of CGCE is essential in facilitating infant feeding. This report highlights that a well-planned surgical excision under LA is a well-tolerated and safer option which is welcomed by parents.

scholarly journals Surgical Excision of Orbital Progressive Granular Cell Tumour

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Demetrio Germanò ◽  
Hossein Mostafa Elbadawy ◽  
Diego Ponzin ◽  
Daniele Ferro ◽  
Leonardo Priore
Keyword(s):  
Ct Scan ◽  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumour ◽  
Granular Cell Tumour ◽  
Initial Examination ◽  
Orbital Mass ◽  
S 100 ◽  
Substantial Progress

Granular cell tumour (GCT) is mostly benign lesion first described by Abrikossoff and named after him. Most cases are reported in the head and neck area, where the tongue is the most common site. Here we review previous cases in the literature for GCT in the orbit and present a new case. A 49-year-old male presented with apparent exophthalmos. Examination of the patient revealed the presence of a mass in the bottom side of the orbit. A substantial progress was noted after two months from the initial examination using computed tomography (CT) scan. An orbital mass was extracted and histological analysis showed signs typical for GCT. Immunohistochemistry was positive for S-100; the biopsy showed no mitotic or necrotic areas. Proptosis was resolved after surgery and a six-year follow-up CT scan was performed. We conclude that rapid progress of the tumour does not necessarily suggest malignancy.

scholarly journals Multiple congenital granular cell tumours of the maxilla and mandible: a rare case report and review of the literature

2021 ◽  
Vol 10 (5) ◽  
pp. 1386-1392
Author(s):  
Jianguo Gan ◽  
Congyu Shi ◽  
Shan Liu ◽  
Xudong Tian ◽  
Xiaoyi Wang ◽  
...  
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Granular Cell ◽  
Review Of The Literature ◽  
Rare Case Report ◽  
Granular Cell Tumours ◽  
Maxilla And Mandible

scholarly journals Congenital granular cell epulis: A case series

2020 ◽  
Vol 9 ◽  
pp. 17
Author(s):  
Mustafa Okumuş ◽  
Adil Umut Zubarioğlu ◽  
Uğuray Payam Hacısalihoğlu
Keyword(s):  
Benign Lesion ◽  
Case Series ◽  
Granular Cell ◽  
Surgical Excision ◽  
Postoperative Recovery ◽  
Alveolar Ridge ◽  
Congenital Granular Cell Epulis ◽  
Malignant Lesions ◽  
Rule Out

Background: Congenital granular cell epulis (CGCE) is an extremely rare intraoral tumor of the newborn with a potential to disrupt feeding and produce respiratory distress. Case Series: We report two newborns presented with mass protruding off the mouth since birth. The mass was arising from alveolar ridge in both cases and dealt with surgical excision. Histopathology revealed it congenital granular cell epulis. Postoperative recovery and follow-up are uneventful. Conclusion: Congenital granular cell epulis is a benign lesion though not quite uncommon, may cause diagnostic challenges. Early excision and histopathology rule out malignant lesions.

Dental Management of Congenital Granular Cell Lesion and Neonatal Teeth: A Case Report

2021 ◽  
Vol 45 (4) ◽  
pp. 269-272
Author(s):  
Min-Kyung Tak ◽  
Jae-Gon Kim ◽  
Yeon-Mi Yang ◽  
Dae-Woo Lee
Keyword(s):  
Case Report ◽  
Oral Cavity ◽  
Granular Cell ◽  
Surgical Excision ◽  
Dental Anomalies ◽  
Dental Papilla ◽  
Dental Management ◽  
Oral Cavity Tumor

Congenital granular cell lesion (CGCL) is a rare benign oral cavity tumor in infants. Neonatal teeth are also rare dental anomalies that appear during the first month of life. This report describes a case of eruption of neonatal teeth after surgical excision of CGCL. Surprisingly, residual neonatal teeth erupted after extraction of the neonatal teeth. If neonatal teeth are mobile, they should be carefully extracted with curettage of the underlying tissues of the dental papilla; failure to curette the socket might result in eruption of odontogenic remnants. If neonatal teeth were exfoliated, parents should be informed of the need for regular checkups with a dentist due to possibility of development of residual neonatal teeth.

scholarly journals Conjunctival Melanocytic Nevi With Granular Cell Change

2019 ◽  
Vol 144 (4) ◽  
pp. 457-465
Author(s):  
Maya Eiger-Moscovich ◽  
Ralph C. Eagle ◽  
Sara E. Lally ◽  
Carol L. Shields ◽  
Jerry A. Shields ◽  
...  
Keyword(s):  
Case Series ◽  
Granular Cell ◽  
Surgical Excision ◽  
Melanocytic Nevus ◽  
Proliferative Index ◽  
Ki 67 ◽  
Melanocytic Nevi ◽  
Pathologic Features ◽  
Mitotic Figures

Context.— Granular cell change in melanocytic nevus is underrepresented in the literature with only 4 well-documented cases, 1 described in the conjunctiva. Unfamiliarity with the clinical and pathologic features of these lesions contributes to the diagnostic difficulty. Objective.— To delineate the clinical and histopathologic features of conjunctival nevi with granular cell change. Design.— In a retrospective observational case series, the medical records of all patients with conjunctival nevi and granular cell change diagnosed between December 2016 and October 2018 were reviewed. Data collected included age, sex, clinical presentation, pathologic findings, and follow-up. Results.— Twelve patients, 6 males and 6 females, with a median age of 14 years (range, 8–82 years) were identified. The nevus manifested as a pigmented, well-circumscribed nodule (7 of 9; 78%) or patch (2 of 9; 22%) in the bulbar and limbal conjunctiva (7 of 9; 78%) or in the plica semilunaris/caruncle (2 of 9; 22%). Cysts were noted in 7 of 9 lesions (78%). Features prompting surgical excision included atypical pigmentation (8 of 9; 89%), growth (7 of 9; 78%), and atypical vascularity (4 of 9; 44%). Microscopically, all lesions comprised a conventional melanocytic nevus with focal granular cell change and immunoreactivity for Melan-A, SOX10, and HMB-45, with Ki-67 proliferative index of less than 2%. Of the 9 lesions with follow-up information, there were no recurrences over mean follow-up of 11.2 months (range, 1–23 months). Conclusions.— Granular cell change in melanocytic nevi is an underrecognized finding that can simulate melanoma clinically and histopathologically. Young age at diagnosis, lack of associated conjunctival melanosis, bulbar location, cysts, and the absence of mitotic figures with a low Ki-67 proliferative index are helpful clinical and pathologic diagnostic clues.

scholarly journals A Single Case Report of Granular Cell Tumor of the Tongue Successfully Treated through 445 nm Diode Laser

Healthcare ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 267
Author(s):  
Maria Vittoria Viani ◽  
Luigi Corcione ◽  
Chiara Di Blasio ◽  
Ronell Bologna-Molina ◽  
Paolo Vescovi ◽  
...  
Keyword(s):  
Diode Laser ◽  
Laser Surgery ◽  
Granular Cell Tumor ◽  
Single Case ◽  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Young Female ◽  
Complete Healing ◽  
Cell Tumor

Oral granular cell tumor (GCT) is a relatively rare, benign lesion that can easily be misdiagnosed. Particularly, the presence of pseudoepitheliomatous hyperplasia might, in some cases, lead to the hypothesis of squamous cell carcinoma. Surgical excision is the treatment of choice. Recurrence has been reported in up to 15% of cases treated with conventional surgery. Here, we reported a case of GCT of the tongue in a young female patient, which was successfully treated through 445 nm diode laser excision. Laser surgery might reduce bleeding and postoperative pain and may be associated with more rapid healing. Particularly, the vaporization effect on remnant tissues could eliminate GCT cells on the surgical bed, thus hypothetically leading to a lower rate of recurrence. In the present case, complete healing occurred in 1 week, and no recurrence was observed after 6 months. Laser surgery also allows the possibility to obtain second intention healing. Possible laser-induced histopathological artifacts should be carefully considered.

Congenital epulis

2005 ◽  
Vol 120 (2) ◽  
pp. 148-150 ◽  
Author(s):  
Sonika Kanotra ◽  
Sohit Paul Kanotra ◽  
J Paul
Keyword(s):  
Granular Cell ◽  
Surgical Excision ◽  
Large Mass ◽  
Uneventful Recovery ◽  
Granular Cell Tumour ◽  
Rare Lesion ◽  
Congenital Epulis ◽  
Feeding Difficulty ◽  
Gingival Mucosa ◽  
Treatable Condition

Congenital epulis or gingival granular cell tumour is a rare lesion occurring in the newborn, affecting females eight times more than males and arising more commonly from the maxillary than the mandibular alveolar ridge. We report the case of a five-day-old girl who presented to us with a large mass arising from the gingival mucosa of the mandible, causing feeding difficulty. Immediate surgical excision was followed by an uneventful recovery. The case is reported to make clinicians aware of this uncommon but easily treatable condition.

scholarly journals Congenital epulis with auto-resolution: case report

2014 ◽  
Vol 62 (3) ◽  
pp. 315-318
Author(s):  
Adriane Sousa de SIQUEIRA ◽  
Márcia Regina Dias de CARVALHO ◽  
Ana Celina Dourado MONTEIRO ◽  
Maria das Graças Rodrigues PINHEIRO ◽  
Lucas Rodrigues PINHEIRO ◽  
...  
Keyword(s):  
Granular Cell Tumor ◽  
Benign Lesion ◽  
Granular Cell ◽  
Cell Types ◽  
Alveolar Ridge ◽  
Normal Oral Mucosa ◽  
Male Baby ◽  
Histological Sections ◽  
Eosinophilic Cytoplasm ◽  
Congenital Epulis

Congenital epulis is an uncommon benign lesion that affects the oral cavity of newborns, and presents histological features which are similar to those of granular cell tumor. The origin of this lesion has not been fully elucidated, and many hypotheses are considered due to the large variety of cell types observed in histological sections. Epulis development occurs further in the prenatal period, and is more common in newborn females, frequently in the maxilla. This lesion usually is presentend as a nodule covered by normal oral mucosa, which in some cases, interferes with baby's breathing and feeding. This report describes the case of a two-month-old male baby who presented a pedunculated intraoral lesion in the mandibular alveolar ridge. Histological sections revealed presence of mucosal fragments with atrophic squamous stratified epithelium, and fibrous connective tissue composed of cells with granular and eosinophilic cytoplasm. A few days after initial exam, the lesion detached from alveolar ridge, and healed spontaneously.

Congenital Granular Cell Lesion: Clinical, Microscopic and Immunohistochemical Aspects in a Case of Multiple Lesions

2011 ◽  
Vol 36 (1) ◽  
pp. 71-74 ◽  
Author(s):  
José Humberto Damante ◽  
Elen de Souza Tolentino ◽  
Reinaldo Mazzottini ◽  
Flávio Monteiro-Amado ◽  
Raul Negrão Fleury ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Present Article ◽  
Granular Cell ◽  
Alveolar Ridge ◽  
Multiple Lesions ◽  
Oral Cavity Tumor ◽  
Congenital Epulis

Congenital granular cell lesion of the newborn, also known as congenital epulis, is a rare benign oral cavity tumor presenting at birth. Usually, it appears as a solitary mass arising in the mouth and originates from the anterior alveolar ridge. The objective of the present article is to report a case of congenital granular cell lesion in an 8-day-old female newborn. The patient presented four intraoral pedunculated lesions. Diagnosis, treatment, microscopic and immunohistochemical characteristics are also discussed.

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