scholarly journals Congenital epulis with auto-resolution: case report

2014 ◽  
Vol 62 (3) ◽  
pp. 315-318
Author(s):  
Adriane Sousa de SIQUEIRA ◽  
Márcia Regina Dias de CARVALHO ◽  
Ana Celina Dourado MONTEIRO ◽  
Maria das Graças Rodrigues PINHEIRO ◽  
Lucas Rodrigues PINHEIRO ◽  
...  
Keyword(s):  
Granular Cell Tumor ◽  
Benign Lesion ◽  
Granular Cell ◽  
Cell Types ◽  
Alveolar Ridge ◽  
Normal Oral Mucosa ◽  
Male Baby ◽  
Histological Sections ◽  
Eosinophilic Cytoplasm ◽  
Congenital Epulis

Congenital epulis is an uncommon benign lesion that affects the oral cavity of newborns, and presents histological features which are similar to those of granular cell tumor. The origin of this lesion has not been fully elucidated, and many hypotheses are considered due to the large variety of cell types observed in histological sections. Epulis development occurs further in the prenatal period, and is more common in newborn females, frequently in the maxilla. This lesion usually is presentend as a nodule covered by normal oral mucosa, which in some cases, interferes with baby's breathing and feeding. This report describes the case of a two-month-old male baby who presented a pedunculated intraoral lesion in the mandibular alveolar ridge. Histological sections revealed presence of mucosal fragments with atrophic squamous stratified epithelium, and fibrous connective tissue composed of cells with granular and eosinophilic cytoplasm. A few days after initial exam, the lesion detached from alveolar ridge, and healed spontaneously.

Obstructive Congenital Gingival Granular Cell Tumor

2003 ◽  
Vol 112 (4) ◽  
pp. 388-391 ◽  
Author(s):  
Jean-Baptiste Charrier ◽  
Pierre Droullé ◽  
Jean-François Chassagne ◽  
Jean-Michel Vignaud ◽  
Michel Stricker
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Surgical Removal ◽  
Alveolar Ridge ◽  
Ultrasound Scan ◽  
Postoperative Course ◽  
Morphological Aspects ◽  
S 100 ◽  
Congenital Epulis

Congenital gingival granular cell tumors (also known as congenital epulis or Neumann's tumor) are rare and always benign intraoral tumors originating from the alveolar ridge. They are typically seen as a mass protruding out of a newborn child's mouth. We report a case of a large obstructive congenital gingival granular cell tumor of the mandibular ridge. The intraoral mass was first detected on a 38-week prenatal ultrasound scan and resulted in neonatal airway obstruction. Complete surgical removal was performed with an uneventful postoperative course. Histologic and immunohistochemical assessments with antibodies against S-100 protein confirmed the diagnosis. The clinical and morphological aspects, differential diagnosis, histogenesis, and treatment are discussed.

Congenital granular-cell tumor of alveolar ridge and tongue

1975 ◽  
Vol 40 (2) ◽  
pp. 270-277 ◽  
Author(s):  
C.T. Dixter ◽  
M.S. Konstat ◽  
J.L. Giunta ◽  
E. Schreier ◽  
G.E. White
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Alveolar Ridge ◽  
Congenital Granular Cell Tumor

Gingival granular cell tumor of the newborn (congenital “epulis”): Ultrastructural observations relating to histogenesis

1982 ◽  
Vol 13 (7) ◽  
pp. 686-689 ◽  
Author(s):  
Ernest E. Lack ◽  
Antonio R. Perez-Atayde ◽  
Trevor J. McGill ◽  
Gordon F. Vawter
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Congenital Epulis

scholarly journals Granular cell tumor that originated in a posterior ethmoid sinus

2017 ◽  
Vol 3 (3) ◽  
pp. 721
Author(s):  
Myung Woo Kim ◽  
Sun Hee Chang ◽  
Ick Soo Choi
Keyword(s):  
Nasal Cavity ◽  
Nasal Polyp ◽  
Granular Cell Tumor ◽  
Neuron Specific Enolase ◽  
Granular Cell ◽  
Ethmoid Sinus ◽  
Cell Tumor ◽  
The Body ◽  
Eosinophilic Cytoplasm ◽  
The Right

<p class="abstract"><span lang="EN-US">A granular cell tumor (GCT) is a rare neoplasm. It grows slowly, presumably originates from a Schwann cell, and is typically benign. Histopathologically, GCTs are composed of loosely infiltrating sheets of large, pale, polyhedral cells with abundant granular eosinophilic cytoplasm and a pale, centrally situated nucleus. Immunohistochemically, GCTs express the S-100 protein and neuron-specific enolase. A GCT can occur anywhere in the body. Half of all GCTs occur in the head and neck regions, especially on the tongue, but they are rarely found in the nasal cavity. A GCT usually arises as a solitary tumor and can be confirmed only by a histologic examination. The appropriate treatment is excision of the lesion. </span>Here, we present a rare case of a GCT originating in the right posterior ethmoid sinus in the nasal cavity. A GCT originating in a posterior ethmoid sinus has not been reported thus far. In our case, a simple nasal polyp was found in the left ethmoid sinus of the patient. Thus, we initially misjudged the GCT in the right nasal cavity as a simple nasal polyp.</p>

scholarly journals Multiple Congenital Epulis in Alveolar Ridges of Maxilla and Mandible in a Newborn: A Rare Case Report

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Nader Saki ◽  
Somayeh Araghi
Keyword(s):  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Respiratory Problems ◽  
Pathologic Features ◽  
Rare Case Report ◽  
Oral Cavity Tumor ◽  
Single Mass ◽  
Congenital Epulis ◽  
Maxilla And Mandible

Congenital granular cell lesion (CGCL) or congenital epulis is an uncommon benign of the oral cavity tumor appearing at birth with typical clinical and pathologic features. It predominately affects females, mainly on the anterior maxillary alveolar ridge, and occurs usually as a single mass, although sometimes as multiple. The left side incisor area is the most common site. The etiology and histogenesis of the lesion remain obscure. Though it is a benign lesion, the tumor may cause feeding and respiratory problems if there are too large or multiple tumors. We report a case of a three-day-old, female newborn, who was referred to our hospital with multiple congenital oral swellings arising from the maxilla and mandible. The tumors caused a feeding problem and, hence, they were resected by surgical excision under general anesthesia.

Congenital epulis and granular cell tumor

1995 ◽  
Vol 80 (6) ◽  
pp. 687-697 ◽  
Author(s):  
Edwin Kaiserling ◽  
Peter Ruck ◽  
Jia-Cheng Xiao
Keyword(s):  
Granular Cell Tumor ◽  
Granular Cell ◽  
Cell Tumor ◽  
Congenital Epulis

scholarly journals Congenital Granular Cell Epulis

2014 ◽  
Vol 138 (1) ◽  
pp. 128-131 ◽  
Author(s):  
Rachel Conrad ◽  
Mia C. N. Perez
Keyword(s):  
Granular Cell Tumor ◽  
Squamous Epithelium ◽  
Neuron Specific Enolase ◽  
Granular Cell ◽  
Cell Tumor ◽  
Alveolar Ridge ◽  
Careful Observation ◽  
Granular Cytoplasm ◽  
S 100 ◽  
Congenital Granular Cell Epulis

Congenital granular cell epulis is a rarely reported lesion of unknown histogenesis with a strong predilection for the maxillary alveolar ridge of newborn girls. Microscopically, it demonstrates nests of polygonal cells with granular cytoplasm, a prominent capillary network, and attenuated overlying squamous epithelium. The lesion lacks immunoreactivity for S-100, laminin, chromogranin, and most other markers except neuron-specific enolase and vimentin. Through careful observation of its unique clinical, histopathologic, and immunohistochemical features, this lesion can be distinguished from the more common adult granular cell tumor as well as other differential diagnoses.

scholarly journals Congenital granular cell epulis: A case series

2020 ◽  
Vol 9 ◽  
pp. 17
Author(s):  
Mustafa Okumuş ◽  
Adil Umut Zubarioğlu ◽  
Uğuray Payam Hacısalihoğlu
Keyword(s):  
Benign Lesion ◽  
Case Series ◽  
Granular Cell ◽  
Surgical Excision ◽  
Postoperative Recovery ◽  
Alveolar Ridge ◽  
Congenital Granular Cell Epulis ◽  
Malignant Lesions ◽  
Rule Out

Background: Congenital granular cell epulis (CGCE) is an extremely rare intraoral tumor of the newborn with a potential to disrupt feeding and produce respiratory distress. Case Series: We report two newborns presented with mass protruding off the mouth since birth. The mass was arising from alveolar ridge in both cases and dealt with surgical excision. Histopathology revealed it congenital granular cell epulis. Postoperative recovery and follow-up are uneventful. Conclusion: Congenital granular cell epulis is a benign lesion though not quite uncommon, may cause diagnostic challenges. Early excision and histopathology rule out malignant lesions.

scholarly journals Congenital granular cell epulis: A rare diagnosis

1970 ◽  
Vol 1 (1) ◽  
pp. 69-72
Author(s):  
B Sigdel ◽  
R Baidya ◽  
P Shrestha ◽  
S Shrestha
Keyword(s):  
Granular Cell Tumor ◽  
Benign Tumor ◽  
Radical Surgery ◽  
Granular Cell ◽  
Female Child ◽  
Cell Tumor ◽  
Congenital Epulis ◽  
Congenital Granular Cell Epulis ◽  
Attending Physician ◽  
Rare Diagnosis

Congenital granular cell tumor is very rare and it arises from the gum pad of neonates. Surgery is required immediatly after birth as the tumor interfares with feeding and respiration. Although a benign tumor, it can create immense anxiety amongst the attending physician and family members. Its recognition is important so as to avoid over diagnosis leading to radical surgery. We report a case of congenital epulis arising from the maxillary alveolar ridge in a newborn female child, which was successfully excised and the diagnosis confirmed histologically. No tumor recurrence has been reported in the patient postoperatively. Keywords: Congenital; Epulis; Granular cell DOI: 10.3126/jpn.v1i1.4458 Journal of Pathology of Nepal (2011) Vol.1, 69-72

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