Congenital epulis

2005 ◽  
Vol 120 (2) ◽  
pp. 148-150 ◽  
Author(s):  
Sonika Kanotra ◽  
Sohit Paul Kanotra ◽  
J Paul

Congenital epulis or gingival granular cell tumour is a rare lesion occurring in the newborn, affecting females eight times more than males and arising more commonly from the maxillary than the mandibular alveolar ridge. We report the case of a five-day-old girl who presented to us with a large mass arising from the gingival mucosa of the mandible, causing feeding difficulty. Immediate surgical excision was followed by an uneventful recovery. The case is reported to make clinicians aware of this uncommon but easily treatable condition.

2021 ◽  
Vol 14 (9) ◽  
pp. e242242
Author(s):  
Zhi Yon Charles Toh ◽  
Thomas Cooper ◽  
Maryam Jessri ◽  
Frank S-C Chang

Granular cell tumour (GCT) is a rare soft tissue lesion which many consider to have malignant potential of yet unknown aetiopathogenesis. Oral GCT lesions may occur in an area of leucoplakia and are predominantly present on the tongue. This case study highlights an uncommon presentation of this condition located on the buccal mucosa and illustrates the need for meticulous evaluation of suspicious lesions. Due to the malignant risk associated with GCT lesions, it is important to make the correct diagnosis and ensure complete surgical excision for these cases. Ongoing long-term follow-up is also indicated to monitor for recurrence or malignancy.


2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Nader Saki ◽  
Somayeh Araghi

Congenital granular cell lesion (CGCL) or congenital epulis is an uncommon benign of the oral cavity tumor appearing at birth with typical clinical and pathologic features. It predominately affects females, mainly on the anterior maxillary alveolar ridge, and occurs usually as a single mass, although sometimes as multiple. The left side incisor area is the most common site. The etiology and histogenesis of the lesion remain obscure. Though it is a benign lesion, the tumor may cause feeding and respiratory problems if there are too large or multiple tumors. We report a case of a three-day-old, female newborn, who was referred to our hospital with multiple congenital oral swellings arising from the maxilla and mandible. The tumors caused a feeding problem and, hence, they were resected by surgical excision under general anesthesia.


2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Demetrio Germanò ◽  
Hossein Mostafa Elbadawy ◽  
Diego Ponzin ◽  
Daniele Ferro ◽  
Leonardo Priore

Granular cell tumour (GCT) is mostly benign lesion first described by Abrikossoff and named after him. Most cases are reported in the head and neck area, where the tongue is the most common site. Here we review previous cases in the literature for GCT in the orbit and present a new case. A 49-year-old male presented with apparent exophthalmos. Examination of the patient revealed the presence of a mass in the bottom side of the orbit. A substantial progress was noted after two months from the initial examination using computed tomography (CT) scan. An orbital mass was extracted and histological analysis showed signs typical for GCT. Immunohistochemistry was positive for S-100; the biopsy showed no mitotic or necrotic areas. Proptosis was resolved after surgery and a six-year follow-up CT scan was performed. We conclude that rapid progress of the tumour does not necessarily suggest malignancy.


2006 ◽  
Vol 121 (2) ◽  
pp. 170-173 ◽  
Author(s):  
T Sasaki ◽  
K Yamamoto ◽  
T Akashi

An extremely rare case of a granular cell tumour arising from the right Kiesselbach's area (Little's area) of the nasal septum is reported. A 69-year-old Japanese woman consulted our clinic and her chief complaints were of continuous serous discharge, stuffiness and occasional slight bleeding from the right nasal cavity. Fibrescopy showed a multilocular mass, which was provisionally considered a nasal polyp. Surgical excision was attempted. During surgery, the tumour shrank markedly following local application of adrenaline, suggestive of hypervascularity. The tumour was successfully excised by careful dissection after cauterisation of the mucosa surrounding the tumour. Histopathological examination revealed morphological features of granular cell tumour immunopositive for S-100 protein. This is the first report of granular cell tumour arising from the Kiesselbach's area in the English literature. The eccentric behaviour of the tumour and the management of a granular cell tumour arising from this area are discussed, together with a literature review.


Author(s):  
Carlos Tavares Bello ◽  
Patricia Cipriano ◽  
Vanessa Henriques ◽  
João Sequeira Duarte ◽  
Conceição Canas Marques

Summary Granular cell tumours (GCT) are rare, slow-growing, benign neoplasms that are usually located in the head and neck. They are more frequent in the female gender and typically have an asymptomatic clinical course, being diagnosed only at autopsy. Symptomatic GCT of the neurohypophysis are exceedingly rare, being less than 70 cases described so far. The authors report on a case of a 28-year-old male that presented to the Endocrinology clinic with clinical and biochemical evidence of hypogonadism. He also reported minor headaches without any major visual symptoms. Further laboratory tests confirmed hypopituitarism (hypogonadotrophic hypogonadism, central hypothyroidism and hypocortisolism) and central nervous system imaging revealed a pituitary macroadenoma. The patient underwent transcranial pituitary adenoma resection and the pathology report described a GCT of the neurohypophysis with low mitotic index. The reported case is noteworthy for the rarity of the clinicopathological entity. Learning points: Symptomatic GCTs are rare CNS tumours whose cell of origin is not well defined that usually give rise to visual symptoms, headache and endocrine dysfunction. Imaging is quite unspecific and diagnosis is difficult to establish preoperatively. Surgical excision is challenging due to lesion’s high vascularity and propensity to adhere to adjacent structures. The reported case is noteworthy for the rarity of the clinicopathological entity.


2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Sarah Bouayyad ◽  
Jen Ong ◽  
Houda Bouayyad ◽  
Heerani Woodun

Abstract Granular cell tumour is a rare, benign tumour that may arise in the soft tissues of various locations. It is often asymptomatic; hence, it gets misdiagnosed as other conditions. This is a case of an asymptomatic 50-year-old male with an incidental finding of a supraglottic lesion during routine oesophagogastroscopy. Examination under general anaesthetic showed a whitish non-ulcerating exophytic lesion on the laryngeal surface of the epiglottis, sparing anterior commissure and vocal cords. Surgical excision was performed with an open supraglottic laryngectomy approach. Histopathology confirmed GCT, strongly positive for S-100 protein and weakly positive for CD68. Accurate histologic analysis is a key to identify this rare tumour among other differentials. Although benign, ongoing monitoring is advised due to risk of recurrence.


2009 ◽  
Vol 2009 ◽  
pp. 1-3 ◽  
Author(s):  
David Bosanquet ◽  
Graham Roblin

Congenital Epulis, also known as Neumann's tumour, is a rare congenital growth affecting the gingival mucosa of neonates. It is benign condition, seen more frequently in females, with multiple Epuli occurring in only 10% of cases. The cause and origin of Congenital Epulis remains unclear. In this article we present a case report of an otherwise healthy female neonate with two Congenital Epuli arising from the upper and lower gingival margin, which were successfully treated with surgical excision. We also present a review of the literature and an estimation of the incidence of Congenital Epulis based on our institutions figures, of 0.0006% (upper 95% confidence interval: 0.0035%).


2019 ◽  
Vol 9 (1) ◽  
pp. 46-50
Author(s):  
E.B. Edetanlen ◽  
C.B. Ogboh

Congenital granular cell tumour of the new born is a rare benign lesion of soft tissues which normally affects the maxillary alveolar ridge in neonates. Though benign, it can cause respiratory embarrassment and prevent feeding causing physical distress to the infant and psychological distress to the parents or guardian. Very few cases are reported in the literature. We aimed to highlight the clinical presentation, management and a brief review of the literature of the lesion.A case of a 3-day old baby who presented to the Oral and Maxillofacial Surgery Clinic University of Benin Teaching Hospital (UBTH) was used to illustrate the clinical presentation and management of congenital epulis.Congenital epulis of the new-born is a rare occurrence, though it can grow to a frightening size, it still remains a benign lesion with li le or no recurrence following surgical excision. The role of counselling to the parents cannot be over-emphasized.Keywords: Congenital, epulis, granular, newborn


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