scholarly journals A Single Case Report of Granular Cell Tumor of the Tongue Successfully Treated through 445 nm Diode Laser

Healthcare ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 267
Author(s):  
Maria Vittoria Viani ◽  
Luigi Corcione ◽  
Chiara Di Blasio ◽  
Ronell Bologna-Molina ◽  
Paolo Vescovi ◽  
...  
Keyword(s):  
Diode Laser ◽  
Laser Surgery ◽  
Granular Cell Tumor ◽  
Single Case ◽  
Benign Lesion ◽  
Granular Cell ◽  
Surgical Excision ◽  
Young Female ◽  
Complete Healing ◽  
Cell Tumor

Oral granular cell tumor (GCT) is a relatively rare, benign lesion that can easily be misdiagnosed. Particularly, the presence of pseudoepitheliomatous hyperplasia might, in some cases, lead to the hypothesis of squamous cell carcinoma. Surgical excision is the treatment of choice. Recurrence has been reported in up to 15% of cases treated with conventional surgery. Here, we reported a case of GCT of the tongue in a young female patient, which was successfully treated through 445 nm diode laser excision. Laser surgery might reduce bleeding and postoperative pain and may be associated with more rapid healing. Particularly, the vaporization effect on remnant tissues could eliminate GCT cells on the surgical bed, thus hypothetically leading to a lower rate of recurrence. In the present case, complete healing occurred in 1 week, and no recurrence was observed after 6 months. Laser surgery also allows the possibility to obtain second intention healing. Possible laser-induced histopathological artifacts should be carefully considered.

Oral granular cell tumors: an analysis of 10 new pediatric and adolescent cases and a review of the literature

2005 ◽  
Vol 29 (1) ◽  
pp. 69-74 ◽  
Author(s):  
Robert Brannon ◽  
Payal Anand
Keyword(s):  
English Language ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumor ◽  
Review Of The Literature ◽  
Soft Tissue Neoplasm ◽  
Adolescent Population ◽  
Male Ratio ◽  
Common Location

Clinicopathologic studies on the granular cell tumor, a submucosal benign soft-tissue neoplasm, have not addressed the pediatric and adolescent population. This study of patients from birth to 19 years of age describes clinically and microscopically 10 new cases and combines them with 24 well-documented pediatric cases previously published in the English-language literature. Of the 34, patient ages ranged from 3 to 19 years (mean age 14.5 years) with a female-to-male ratio of 3.3 to 1. The most common location was the tongue (50%) and lips (25%). In neoplasms whose epithelial findings were documented microscopically, a reactive pseudoepitheliomatous (pseudocarcinomatous) hyperplasia of the overlying epithelium occurred in 29%. The recurrence rate was less than 10% following conservative surgical excision. This study reveals that an oral granular cell tumor in the first decade of life is an uncommon event and discusses the importance of differentiating between squamous cell carcinoma and granular cell tumor.

scholarly journals Biliary Duct Granular Cell Tumor: A Rare But Surgically Curable Benign Tumor

HPB Surgery ◽  
1993 ◽  
Vol 6 (4) ◽  
pp. 311-317 ◽  
Author(s):  
W. David Lewis ◽  
Joseph F. Buell ◽  
Roger L. Jenkins ◽  
Peter A. Burke
Keyword(s):  
Granulosa Cell ◽  
Granular Cell Tumor ◽  
Granulosa Cell Tumor ◽  
Granular Cell ◽  
Surgical Excision ◽  
Biliary Tree ◽  
Cell Tumor ◽  
The Body ◽  
Benign Tumors ◽  
Biliary Duct

Granulosa cell tumors are rare benign tumors which may be found throughout the body. Rare cases are isolated within the biliary tree. If completely resected, surgical excision is curative.A case of biliary duct granulosa cell tumor is presented with review of the world’s literature on this topic.

scholarly journals Granular Cell Tumor over the Mons Pubis: An Uncommon Tumor

2019 ◽  
Vol 2019 ◽  
pp. 1-3 ◽  
Author(s):  
M. Patabendige ◽  
D. J. Wickramasooriya ◽  
L. Dasanayake
Keyword(s):  
Soft Tissue ◽  
Granular Cell Tumor ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumor ◽  
The Body ◽  
Complete Surgical Excision ◽  
Neural Origin ◽  
Labium Majus ◽  
Uncommon Tumor

Granular cell tumors are uncommon, usually benign, soft tissue neoplasms of neural origin. They occur throughout the body; vulval involvement is uncommon and labium majus is the commonest site in vulva. Complete surgical excision is the preferred treatment of choice to prevent recurrence. Here, we present a benign granular cell tumor over the mons pubis of vulva in a 27-year-old woman.

Perianal Granular Cell Tumor: Report of a Case and Review of the Literature

2009 ◽  
Vol 95 (4) ◽  
pp. 538-541 ◽  
Author(s):  
Massimiliano Mistrangelo ◽  
Paola Cassoni ◽  
Gitana Scozzari ◽  
Isabella Castellano ◽  
Giorgia Gavello ◽  
...  
Keyword(s):  
Literature Search ◽  
Granular Cell Tumor ◽  
Clinical Course ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumor ◽  
Pathological Examination ◽  
Perianal Region ◽  
Therapeutic Procedures

Introduction Granular cell tumor was first described by Abrikossoff in 1926. Over the years several cases of this neoplasm have been reported, with a variety of localizations. We here report a case of perianal granular cell tumor and discuss its histogenesis and its relevance to clinical practice. Methods The clinical course and histopathology of the case are reviewed, and a literature search for other reported cases has been performed. Results A 46-year-old woman presented with a perianal nodular lesion. Pathological examination revealed a granular cell tumor. A literature search produced only 25 other cases of anal and perianal granular cell tumors. Conclusions Granular cell tumors are rarely observed in the perianal region. Their existence must always be borne in mind in the differential diagnosis of perianal neoplasms. In most cases surgical excision is curative, but potential malignant transformation must be considered during therapeutic procedures and follow-up.

scholarly journals Surgical Excision Of Intraoral Lipoma; Case Report

2016 ◽  
Vol 12 (12) ◽  
pp. 211
Author(s):  
Ahmed Ismail Nagy
Keyword(s):  
Case Report ◽  
Granular Cell Tumor ◽  
Clinical Presentation ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumor ◽  
Lower Lip ◽  
Floor Of The Mouth ◽  
The Common ◽  
Oral Tumors

Lipoma is a common tumor of soft tissue. Its location on the oral mucosa is rare, representing 1% to 5% of benign oral tumors although it is the most mesenchymal tumor of the trunk and proximal portions of extremities. Lipoma of the oral cavity may occur in any region. The buccal mucosa, tongue, and floor of the mouth are among the common locations. The clinical presentation is typically as an asymptomatic yellowish mass. The overlying epithelium is intact, and superficial blood vessels are usually evident over the tumor. Other benign connective tissue lesions such as granular cell tumor, neurofibroma, traumatic fibroma and salivary gland lesions (mucocele and mixed tumor) might be included in differential diagnosis. We present a case report of oral lipoma in the left side of the lower lip in 18 years old Saudi patient.

scholarly journals Granular Cell Tumor Presenting as a Tracheal Mass in a 17-year-old Female

2008 ◽  
Vol 23 (1) ◽  
pp. 39-40
Author(s):  
Jose M. Carnate ◽  
Audie G. Silva
Keyword(s):  
Tumor Cells ◽  
Granular Cell Tumor ◽  
S100 Protein ◽  
Granular Cell ◽  
Surgical Excision ◽  
Cell Tumor ◽  
Granular Cytoplasm ◽  
History Of ◽  
Infiltrative Growth Pattern ◽  
One Year

Granular cell tumors involving the trachea are rare. We present the case of a seventeen year old female with a one year history of gradually worsening dyspnea necessitating a tracheotomy. A suprastomal intraluminal tracheal mass was excised. Histologic sections (Figure 1) show a poorly circumscribed neoplasm infiltrating through the tracheal cartilage. It is composed of polygonal to somewhat elongated tumor cells that have small, dark nuclei. The cytoplasm is ample, eosinophilic and strikingly granular in quality. The cell borders are ill-defined creating a `syncytial’ pattern of dark nuclei scattered in a sea of granular cytoplasm. The diagnosis was a granular cell tumor. Immunohistochemistry (Figure 2) revealed strong, diffuse cytoplasmic positivity for S100 protein, attesting to its neural crest histogenesis. The infiltrative growth pattern may momentarily raise the question of malignancy but this is dispelled by awareness that infiltration is the natural history for all granular cell tumors, benign or malignant. Histologically, malignancy is diagnosed if three or more of the following are present: necrosis, spindling of tumor cells, vesicular nuclei with large nucleoli, greater than 2 mitoses per ten high power fields, high nucleus-to-cytoplasm ratio and nuclear pleomorphism. None was present in our case. Surgical excision remains the mainstay of treatment.

scholarly journals Granular Cell Tumor on the soft palate: a very rare location

2015 ◽  
Vol 21 (1) ◽  
pp. 58
Author(s):  
Willian Pecin Jacomacci
Keyword(s):  
Soft Palate ◽  
Granular Cell Tumor ◽  
Benign Lesion ◽  
Granular Cell ◽  
Soft Tissue Tumors ◽  
Cell Tumor ◽  
Neural Origin ◽  
Rare Location ◽  
Rare Lesion ◽  
Immunohistochemical Analyses

<p>Granular cell tumor (GCT) is a rare lesion of neural origin and uncertain nature. It can be a true neoplasm, a degenerative metabolic process or a proliferation trauma-induced. In general, it appears as a singular benign lesion, however, there are rare cases that are malignant multicentric forms. The most frequent orofacial localization is the tongue.  The aim of this report was to describe a case of GCT occurring on  the soft palate. Patient presented a discrete and asymptomatic nodule for approximately eight months. Definitive diagnosis of granular cell tumor was established by histological and immunohistochemical analyses. The case illustrates the occurrence of granular cell tumor in an unusual region and emphasizes the importance of including this entity in differential diagnosis of soft tissue tumors in otherwise locations besides the tongue. </p>

scholarly journals Coexisting Granular Cell Tumor and Tubular Adenoma of the Ileocecal Valve

2018 ◽  
Vol 12 (1) ◽  
pp. 7-12
Author(s):  
Jonathan Gapp ◽  
John Gross ◽  
Lakshmi Chintalacheruvu ◽  
Savio Reddymasu
Keyword(s):  
Rare Case ◽  
Granular Cell Tumor ◽  
Ileocecal Valve ◽  
Granular Cell ◽  
Young Female ◽  
Cell Tumor ◽  
Tubular Adenoma ◽  
Modus Operandi ◽  
Simple Observation ◽  
Few Data

Granular cell tumors (GCTs) have been described as neoplasms of Schwann cell origin. They are often benign and notably uncommon in the gastrointestinal tract. Recently, their incidence has become more common, likely as a result of increased colonoscopy screenings. Very few data exist regarding their potential for malignancy, but malignant GCTs have been reported. Here, we report the case of a young female patient who was diagnosed with an atypical GCT on the ileocecal valve with an overlying tubular adenoma which was found incidentally on colonoscopy. This represents the first known report of a GCT with atypical features on the ileocecal valve, as well as a rare case of overlying adenomatous changes. Due to the paucity of cases, there is no clear modus operandi for their management. Furthermore, it is not clear whether surgical or endoscopic interventions or simple observation may be most appropriate. Further studies are needed to evaluate the potential for malignancy of this tumor, as well as its management.

scholarly journals Malignant granular cell tumor of the arm – case report

2021 ◽  
Vol 4 (1) ◽  
pp. 3-8
Author(s):  
Mihai Mehedinţu ◽  
Răzvan Danciu ◽  
Anca I. Toma ◽  
Corina Ştefan ◽  
Cristian R. Jecan
Keyword(s):  
Granular Cell Tumor ◽  
Clinical Presentation ◽  
Histopathological Examination ◽  
Granular Cell ◽  
Surgical Excision ◽  
Female Gender ◽  
Cell Tumor ◽  
Malignant Granular Cell Tumor ◽  
Tissue Cancer

Abstract Granular cell tumor (GCT) is a rare form of soft tissue cancer that is usually benign. Its malignant evolution is encountered in less than 2% of cases, having a more rapid and unfavorable evolution. Clinical presentation betraying malignant features could be increased tumor size, rapid growth, deep localization, and female gender. This paper presents the case of a 52-year-old patient with a hard, rapidly evolving tumor in the left arm. The diagnosis of granular cell tumor was made based on histopathological examination using the Fanburg and Smith criteria to differentiate the formation as malignant, but with certainty this was subsequently confirmed by the existence of a metastasis. Surgical excision was performed and the evolution was favorable. Evolution and treatment differ depending on the benign or malignant form, but surgical treatment with wide local excision is recommended. This may be followed by chemotherapy or radiotherapy, and follow-up of patients for the rest of their lives is mandatory.

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