scholarly journals Postanesthetic Severe Oral Angioedema in Patient’s Taking Angiotensin-Converting Enzyme Inhibitor

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Acílio Marques ◽  
Carla Retroz-Marques ◽  
Sara Mota ◽  
Raquel Cabral ◽  
Matos Campos

Angiotensin-converting enzyme (ACE) inhibitors are the leading cause of a drug-induced angioedema. This occurrence is frequently underdiagnosed, but its relapse can be life-threatening. The authors’ intention in reporting this clinical case is to sound a warning about reviewing attitudes and surveillance to try to improve patient perioperative safety.

2014 ◽  
Vol 11 (4) ◽  
pp. 75-78
Author(s):  
D A Napalkov

In the form of the literature review we shows the concept of the treatment of high-risk hypertensive patients, who have been taking ACE inhibitors which application is the most advanced approach from the perspective of evidence-based cardiology. One of the most studied drugs is perindopril. The article deals with the data on the special properties of perindopril molecules, as well as on the possibilities of using perindopril and indapamide combination, as well as on usage of indapamide and amlodipine for the realization of protective mechanism. At the conclusion of the article we offered the differentiated approach to the usage of different drugs containing perindopril for different indications.


2019 ◽  
Vol 32 (11) ◽  
pp. 714
Author(s):  
Joana Cosme ◽  
Amélia Spínola ◽  
Manuel Branco Ferreira ◽  
Manuel Pereira Barbosa

Introduction: Hospitalizations due to angioedema are important especially in debilitating or life-threatening situations. The aim of this study was to evaluate the frequency and etiology of angioedema without urticaria in hospital admissions.Material and Methods: The admissions between 2009 and 2013 in Centro Hospitalar Lisboa Norte with a diagnosis grouped under the ICD9 codes of angioedema were retrospectively analysed. The episodes of angioedema with urticaria were excluded. The admissions were categorized into 2 groups: A — hospitalizations motivated by the angioedema; B — hospitalizations in which the angioedema was an incidental finding.Results: There were 169 hospitalizations (52% females, 96% adults, mean age 52 ± 20.8 years), distributed by 23 hospital departments, 51% in the Immunoallergology department. The mean annual angioedema admission rate was 72/100 000. In 68% of the cases, angioedema was the cause for the admission; in 32% an incidental finding. In 38% there was upper airway involvement. The etiologies were: hereditary angioedema in 24%, angiotensin converting enzyme inhibitor induced angioedema in 31%, idiopathic angioedema in 21%, thrombolysis induced angioedema in 13%, nonsteroidal anti-inflammatory drug-induced angioedema in 5%.Discussion: The main etiology was angiotensin converting enzyme inhibitor angioedema, followed by hereditary angioedema and thrombolysis induced angioedema, and these findings concur with the international literature.Conclusion: The mean annual angioedema admission rate was 72/100 000 and there was airway involvement in 38% of hospitalizations.


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