scholarly journals A Gastrointestinal Electrical Stimulation System Based on Transcutaneous Power Transmission Technology

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Bingquan Zhu ◽  
Yongbing Wang ◽  
Guozheng Yan ◽  
Pingping Jiang ◽  
Zhiqiang Liu

Electrical stimulation has been suggested as a possible treatment for various functional gastrointestinal disorders (FGID). This paper presents a transcutaneous power supplied implantable electrical stimulation system. This technology solves the problem of supplying extended power to an implanted electrical stimulator. After implantation, the stimulation parameters can be reprogrammed by the external controller and then transmitted to the implanted stimulator. This would enable parametric studies to investigate the efficacy of various stimulation parameters in promoting gastrointestinal contractions. A pressure detector in the internal stimulator can provide real-time feedback about variations in the gastrointestinal tract. An optimal stimulation protocol leading to cecal contractions has been proposed: stimulation bursts of 3 ms pulse width, 10 V amplitude, 40 Hz frequency, and 20 s duration. The animal experiment demonstrated the functionality of the system and validated the effects of different stimulation parameters on cecal contractions.

2022 ◽  
Vol 12 (1) ◽  
pp. 76
Author(s):  
Jeonghee Kim ◽  
Thomas Wichmann ◽  
Omer T. Inan ◽  
Stephen P. DeWeerth

(1) Background: Non-invasive neuromodulation is a promising alternative to medication or deep-brain stimulation treatment for Parkinson’s Disease or essential tremor. In previous work, we developed and tested a wearable system that modulates tremor via the non-invasive, electrical stimulation of peripheral nerves. In this article, we examine the proper range and the effects of various stimulation parameters for phase-locked stimulation. (2) Methods: We recruited nine participants with essential tremor. The subjects performed a bean-transfer task that mimics an eating activity to elicit kinetic tremor while using the wearable stimulation system. We examined the effects of stimulation with a fixed duty cycle, at different stimulation amplitudes and frequencies. The epochs of stimulation were locked to one of four phase positions of ongoing tremor, as measured with an accelerometer. We analyzed stimulation-evoked changes of the frequency and amplitude of tremor. (3) Results: We found that the higher tremor amplitude group experienced a higher rate of tremor power reduction (up to 65%) with a higher amplitude of stimulation when the stimulation was applied at the ±peak of tremor phase. (4) Conclusions: The stimulation parameter can be adjusted to optimize tremor reduction, and this study lays the foundation for future large-scale parameter optimization experiments for personalized peripheral nerve stimulation.


Electronics ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. 1156
Author(s):  
Tyler Ward ◽  
Neil Grabham ◽  
Chris Freeman ◽  
Yang Wei ◽  
Ann-Marie Hughes ◽  
...  

We present biphasic stimulator electronics developed for a wearable functional electrical stimulation system. The reported stimulator electronics consist of a twenty four channel biphasic stimulator. The stimulator circuitry is physically smaller per channel and offers a greater degree of control over stimulation parameters than existing functional electrical stimulator systems. The design achieves this by using, off the shelf multichannel high voltage switch integrated circuits combined with discrete current limiting and dc blocking circuitry for the frontend, and field programmable gate array based logic to manage pulse timing. The system has been tested on both healthy adults and those with reduced upper limb function following a stroke. Initial testing on healthy users has shown the stimulator can reliably generate specific target gestures such as palm opening or pointing with an average accuracy of better than 4 degrees across all gestures. Tests on stroke survivors produced some movement but this was limited by the mechanical movement available in those users’ hands.


2012 ◽  
Author(s):  
Erica D. Sood ◽  
Jennifer Shroff Pendley ◽  
Alicia O. Fisher ◽  
Prateek Wali ◽  
Fernando Del Rosario

Author(s):  
Yvan Vandenplas ◽  
◽  
Bruno Hauser ◽  
Silvia Salvatore ◽  
◽  
...  

Цель. Функциональные гастроинтестинальные расстройства (ФГИР), такие как колики, запоры и регургитация, встречаются практически у 1/2 младенцев. Целью данной публикации является предоставление врачами современного обзора данных по влиянию ФГИР на здоровье семьи и ребенка, а также практических рекомендаций по ведению данных пациентов. Материалы и методы. Проанализированы руководства и экспертные рекомендации. Результаты. ФГИР являются частой причиной беспокойства родителей и ухудшения качества жизни ребенка и членов семьи. Кроме того, они опре-деляют существенные финансовые затраты родителей, страховых компаний и системы здравоохранения в целом. Первичной задачей ведения мла-денцев с ФГИР является уменьшение выраженности симптомов у ребенка и улучшение качества жизни семьи. В тех случаях, когда тактика ведения не ограничивается успокоением родителей, адекватная диетотерапия может быть рекомендована как эффективный и наиболее безопасный метод. Заключение. К основным задачам специалистов в области здравоохранения при ведении детей с ФГИР относятся успокоение родителей, опре-деление оптимальной тактики диетотерапии и ограничение необоснованного использования медикаментов. Ключевые слова: запор, функциональные гастроинтестинальные расстройства, младенец, младенческие колики, питание, регургитация, рефлюкс. Для цитирования: Vandenplas Y., Hauser B., Salvatore S. Функциональные гастроинтестинальные расстройства: влияние на здоровье ребенка и семьи. Педиатрия. Consilium Medicum. 2020; 1: 36–41. DOI: 10.26442/26586630.2020.1.190721


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