scholarly journals RecurrentC. difficilein a Patient with IgG Deficiency

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Asad Jehangir ◽  
Kyle Bennett ◽  
Shoaib Bilal Fareedy ◽  
Andrew Rettew ◽  
Bilal Shaikh ◽  
...  
Keyword(s):  
Case Report ◽  
Healthcare Costs ◽  
Middle Age ◽  
Recurrent Infections ◽  
Fecal Transplant ◽  
Short Span ◽  
Igg Deficiency ◽  
One Year ◽  
Recurrent Pyogenic Infections

IgG deficiency can predispose to recurrent pyogenic infections. The association of IgG deficiency withClostridium difficileinfection has been infrequently reported in the literature. We present a case of a middle-age woman with multiple hospitalizations for recurrentC. difficilein a short span of time which prompted consideration of a possible fecal transplant. On evaluation, she was found to have low total IgG, with subclass analysis revealing low IgG1 and IgG3. She was started on monthly infusions of immunoglobulins and one year after her last episode ofC. difficileshe has not had any recurrence. The role of immunoglobulin infusion in the treatment of recurrentC. difficileis controversial, with some studies revealing no clear evidence of benefit. Our case report suggests that the patients who have underlying IgG deficiency may benefit from immunoglobulin, as this can significantly reduce the incidence of recurrent infections and hence save the healthcare costs.

scholarly journals Role of Histopathological Analysis in Diagnosing Steroid Cell Tumour: A Case Report

2019 ◽  
Vol 2 (1) ◽  
pp. 91-94
Author(s):  
S R Ohayi
Keyword(s):  
Case Report ◽  
Small Proportion ◽  
Middle Age ◽  
Abdominal Mass ◽  
Cell Tumour ◽  
Histopathological Analysis ◽  
Rare Tumour ◽  
Histopathological Features ◽  
Not Otherwise Specified

Steroid cell tumour of the ovary is an extremely rare tumour. They are classified into three types with the commonest, the steroid cell tumour not otherwise specified (NOS) consisting approximately 60% of them. They occur mostly in middle age, are mostly benign and mostly cause virilising symptoms though a small proportion can present with oestrogenic effects. Diagnosis is based on presence of symptoms, presence of specific histopathological features with absence of certain histopathological features and positive specific immunostaining results. Here the author reports a case of a 42-year old woman with abdominal mass but without virilising symptoms but on whom a diagnosis of ovarian steroid cell tumour was reached by histopathological analysis which revealed presence of specific histopathological features with absence of certain histopathological features.

scholarly journals Role of Chitosan In Lymphoedema

2020 ◽  
Vol 2 (01) ◽  
pp. 01-03
Author(s):  
Ravi Chittoria
Keyword(s):  
Case Report ◽  
Recurrent Infections ◽  
Skin Changes ◽  
Increased Risk ◽  
Prevention Of Infections ◽  
Main Components ◽  
Chronic Problem

Lymphoedema is a chronic problem with various skin changes that lead to impaired care for the affected limb. These skin changes also lead to recurrent infections. The difficulty in care and the subsequent neglect leads to further spread of the infection and increased risk of future infections. Prevention of infections and prevention of progress of the skin changes is one of the main components of the treatment of the lymphoedema. There are various materials available to enhance the healing of the knobs and fissures secondary to lymphoedema. We would like to present our case report on the usage of chitosan in a patient with stage 7 skin changes of lymphedema.

scholarly journals Role of Histopathological Analysis in Diagnosing Steroid Cell Tumour: A Case Report

2019 ◽  
Vol 2 (1) ◽  
pp. 91-94
Author(s):  
S R Ohayi
Keyword(s):  
Case Report ◽  
Small Proportion ◽  
Middle Age ◽  
Abdominal Mass ◽  
Cell Tumour ◽  
Histopathological Analysis ◽  
Rare Tumour ◽  
Histopathological Features ◽  
Not Otherwise Specified

Steroid cell tumour of the ovary is an extremely rare tumour. They are classified into three types with the commonest, the steroid cell tumour not otherwise specified (NOS) consisting approximately 60% of them. They occur mostly in middle age, are mostly benign and mostly cause virilising symptoms though a small proportion can present with oestrogenic effects. Diagnosis is based on presence of symptoms, presence of specific histopathological features with absence of certain histopathological features and positive specific immunostaining results. Here the author reports a case of a 42-year old woman with abdominal mass but without virilising symptoms but on whom a diagnosis of ovarian steroid cell tumour was reached by histopathological analysis which revealed presence of specific histopathological features with absence of certain histopathological features.

Safe neoadjuvant trastuzumab-based treatment in HER2 + inflammatory early breast cancer in a glucose 6-phosphate dehydrogenase-deficient postmenopausal woman: A case report and review of the literature

2019 ◽  
Vol 26 (2) ◽  
pp. 492-495
Author(s):  
Alberto J Cunquero-Tomás ◽  
Claudio D Ávila-Andrade ◽  
Javier Milara ◽  
Karla Javier ◽  
Vega Iranzo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Report ◽  
Early Breast Cancer ◽  
Pathologic Response ◽  
Review Of The Literature ◽  
Adjuvant Trastuzumab ◽  
Hemolytic Crisis ◽  
One Year ◽  
Glucose 6 Phosphate Dehydrogenase

Introduction Glucose 6-phosphate dehydrogenase (G6PD) is a basic antioxidant pathway for erythrocytes, being its deficiency the most common gene mutation worldwide. As breast cancer is one of the most frequent tumors, many of these patients may present with G6PD deficiency prior treatment without notice. Case report We present the case of a woman deficient for G6PD with the diagnosis of Stage IIIB (cT4d cN1 cM0) HER2-enriched early breast cancer. Management and outcome The patient underwent neoadjuvance with trastuzumab and anthracycline-free chemotherapy, based on docetaxel (75 mg/m2, 120 mg) and carboplatin (AUC 5, 560 mg). She did not present hemolytic crisis and no blood transfusions were needed. She achieved a good pathologic response and completed one-year adjuvant trastuzumab without incidences. Discussion Although the role of HER2 and trastuzumab in oxidative stress is not yet completely understood, we suggest that trastuzumab may be a suitable agent for treatment in patients with HER2-enriched breast cancer in a non-oxidative chemotherapy scheme, with acceptable responses and no triggering hemolytic crisis.

scholarly journals Role of Histopathological Analysis in Diagnosing Steroid Cell Tumour: A Case Report

2019 ◽  
Vol 2 (1) ◽  
pp. 91-94
Author(s):  
S R Ohayi
Keyword(s):  
Case Report ◽  
Small Proportion ◽  
Middle Age ◽  
Abdominal Mass ◽  
Cell Tumour ◽  
Histopathological Analysis ◽  
Rare Tumour ◽  
Histopathological Features ◽  
Not Otherwise Specified

Steroid cell tumour of the ovary is an extremely rare tumour. They are classified into three types with the commonest, the steroid cell tumour not otherwise specified (NOS) consisting approximately 60% of them. They occur mostly in middle age, are mostly benign and mostly cause virilising symptoms though a small proportion can present with oestrogenic effects. Diagnosis is based on presence of symptoms, presence of specific histopathological features with absence of certain histopathological features and positive specific immunostaining results. Here the author reports a case of a 42-year old woman with abdominal mass but without virilising symptoms but on whom a diagnosis of ovarian steroid cell tumour was reached by histopathological analysis which revealed presence of specific histopathological features with absence of certain histopathological features.

scholarly journals Ocular manifestation in progeria: A case report

2020 ◽  
Vol 12 (1) ◽  
pp. 133-138
Author(s):  
Rinkal Suwal ◽  
Pranita Dhakal ◽  
Purushottam Joshi
Keyword(s):  
Case Report ◽  
Bright Light ◽  
Ocular Manifestations ◽  
First Case ◽  
Musculoskeletal Abnormalities ◽  
One Year ◽  
Progeria Syndrome ◽  
Hutchinson Gilford Progeria Syndrome ◽  
Delayed Growth

Introduction: Progeria also known as Hutchinson Gilford Progeria Syndrome (HGPS) (MIM176670) is a very uncommon fatal genetic untimely aging syndrome. It is characterized by retarded physical development, accelerated degeneration of the skin, cardiovascular and musculoskeletal abnormalities. Other features include prominent eyes, thin nose, small chin and thin lips. Eyebrow hair loss, madarosis and lagopththalmos are the common ocular manifestations. Case: We report a case of five year old boy with complaints of discomfort in bright light and a whitish appearance in his right eye for two months. He was accompanied by the parents. They complained of loss of eyelashes and eyebrows. In the developmental history he was normal at birth till the age of one year then they noticed gradual hair fall, delayed growth, wrinkling of skin, increase in size of head and thinning of limbs. Conclusion: This is the first case report from Nepal with the ocular presentation of progeria indicating the role of ocular senescence in patients with Hutchinson Progeria Gilford Syndrome.

scholarly journals Primary pulmonary Echinococcosis: A case report

2016 ◽  
Vol 9 (1) ◽  
pp. 66
Author(s):  
Md. Rafiqul Alam ◽  
Md. Abul Kalam Azad ◽  
Zia Uddin Ahmed ◽  
Md. Mizanur Rahman Khan ◽  
Ferdous Jahan ◽  
...  
Keyword(s):  
Case Report ◽  
Middle Age ◽  
Pulmonary Involvement ◽  
Parasitic Disease ◽  
Positive Serology ◽  
The World ◽  
One Year ◽  
Pulmonary Echinococcosis

Echinococcosis is a parasitic disease endemic in many parts of the world. Liver is the most common affected organ followed by lungs. Primary pulmonary involvement is very rare. In this case report, we are going to present a case of primary pulmonary echinococcosis in a middle age female. She was presented with cough and haemoptysis. She was initially labeled and treated as a case of consolidation with different antibiotics in appropriate dose and duration without clinical and radiological improvement. So she was evaluated further and diagnosed as a case of primary pulmonary echinococcosis on the basis of histopathology and positive serology for Echinococcal antigen. She was advised to take oral Albendazole 400mg 12 hourly for one year with regular follow-up.

scholarly journals Human Capital and the Lifetime Costs of Impatience

2015 ◽  
Vol 7 (3) ◽  
pp. 126-153 ◽  
Author(s):  
Brian C. Cadena ◽  
Benjamin J. Keys
Keyword(s):  
Human Capital ◽  
Middle Age ◽  
Investment Decision ◽  
Dropping Out ◽  
Human Capital Formation ◽  
Lifetime Costs ◽  
Using Data ◽  
One Year ◽  
Exponential Discounting

In this paper, we examine the role of impatience in human capital formation—arguably the most important investment decision individuals make during their lifetimes. We focus on a set of investment behaviors that cannot be explained solely by variation in exponential discounting. Using data from the NL SY and a straightforward measure of impatience, we find that impatient people more frequently invest in dynamically inconsistent ways, such as dropping out of college with one year or less remaining. The cumulative investment differences result in the impatient earning 13 percent less and expressing more regret as this cohort reaches middle age. (JEL D91, I26, J24, J31)

The Role of Navigation and Ultrasound Piezosurgery in the Surgical Treatment of Hypertelorism: A Case Report

2014 ◽  
Vol 75 (S 02) ◽  
Author(s):  
S. Heredero ◽  
J. Solivera ◽  
A. Romance ◽  
A. Dean ◽  
J. Lozano
Keyword(s):  
Case Report ◽  
Surgical Treatment
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