scholarly journals Clinical Impact of Prophylactic Antibiotic Treatment for Self-Expandable Metallic Stent Insertion in Patients with Malignant Colorectal Obstruction

2015 ◽  
Vol 2015 ◽  
pp. 1-7
Author(s):  
Jong-Sun Kim ◽  
Wan-Sik Lee ◽  
Cho-Yun Chung ◽  
Hyung-Chul Park ◽  
Dae-Seong Myung ◽  
...  
Keyword(s):  
Risk Factor ◽  
Prophylactic Antibiotic ◽  
Infectious Complications ◽  
Stent Insertion ◽  
Metallic Stent ◽  
Colorectal Obstruction ◽  
Propensity Score Matching Analysis ◽  
Expandable Metallic Stent ◽  
Potential Risk Factors ◽  
Prophylactic Antibiotic Treatment

Purpose. The aim of this study was to determine the efficacy of prophylactic antibiotics (PA) for reducing the infectious complications and the potential risk factors responsible for the infectious complications after stent insertion for malignant colorectal obstruction.Methods. We performed a retrospective review of 224 patients who underwent self-expandable metallic stent (SEMS) insertion for malignant colorectal obstruction from May 2004 to December 2012.Results. There were 145 patients in the PA group and 79 in non-PA group. The CRP level in PA group was significantly higher than that in non-PA. Abdominal tenderness and mechanical ileus were significantly more frequent in PA group than those in non-PA. The frequency of post-SEMS insertion fever, systemic inflammatory response syndrome (SIRS), and bacteremia was not significantly different between PA and non-PA groups. In multivariate analysis, the CRP level was risk factor related to post-SEMS insertion SIRS. However, in propensity score matching analysis, there was no independent risk factor related to post-SEMS insertion fever, SIRS, and bacteremia.Conclusion. The use of PA in patients with malignant colorectal obstruction may be not effective to prevent the development of infectious complications after SEMS insertion.

Self-expandable Metallic Stent Insertion for Nonresectable Esophageal Cancer Patients.

2001 ◽  
Vol 52 (2) ◽  
pp. 75-81
Author(s):  
Hideo Shimada ◽  
Osamu Chino ◽  
Takayuki Nishi ◽  
Hikaru Tanaka ◽  
Yoshifumi Kise ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Cancer Patients ◽  
Stent Insertion ◽  
Metallic Stent ◽  
Expandable Metallic Stent

Metallic Stent for Malignant Colorectal Obstruction

2018 ◽  
Vol 02 (01) ◽  
pp. 046-052
Author(s):  
Yoshitaka Inaba ◽  
Yozo Sato
Keyword(s):  
Stent Migration ◽  
Late Complications ◽  
Secondary Outcome ◽  
Successful Implementation ◽  
Metallic Stent ◽  
Bridge To Surgery ◽  
Success Rates ◽  
Sems Placement ◽  
Colorectal Obstruction ◽  
Expandable Metallic Stent

AbstractAcute colorectal obstruction has been often reported as a secondary outcome of left-colonic malignancy. It is considered as a common emergency condition. Self-expandable metallic stent (SEMS) placement is widely used as a palliative treatment for the management of malignant colorectal obstruction (MCRO). SEMS placement is also deliberated as a bridge to surgery. With advances in technology, several recent studies of SEMS placement for MCRO indicated high technical (94–98%) and clinical (91–93%) success rates. The complication rate associated with SEMS is quite acceptable. However, long-term outcomes are still unclear. The symptoms should be carefully monitored before application of SEMS, particularly in patients who are eligible for systemic chemotherapy and in patients with a long life expectancy because of late complications such as reobstruction, stent migration, and perforation. Appropriate patient selection and placement technique are keys for the successful implementation of SEMS.

scholarly journals Serious Complications after Self-expandable Metallic Stent Insertion in a Patient with Malignant Lymphoma

2015 ◽  
Vol 78 (1) ◽  
pp. 31 ◽  
Author(s):  
Sung Bae Cho ◽  
Seon Ah Cha ◽  
Joon Young Choi ◽  
Jong Min Lee ◽  
Hyeon Hui Kang ◽  
...  
Keyword(s):  
Malignant Lymphoma ◽  
Stent Insertion ◽  
Metallic Stent ◽  
Expandable Metallic Stent

scholarly journals Endoscopic biliary self-expandable metallic stent in malignant biliary obstruction with or without sphincterotomy: systematic review and meta-analysis

2019 ◽  
Vol 07 (01) ◽  
pp. E26-E35 ◽  
Author(s):  
Benedetto Mangiavillano ◽  
Amedeo Montale ◽  
Leonardo Frazzoni ◽  
Mario Bianchetti ◽  
Amrita Sethi ◽  
...  
Keyword(s):  
Adverse Events ◽  
Success Rate ◽  
Meta Analysis ◽  
Stent Insertion ◽  
Metallic Stent ◽  
Success Rates ◽  
Technical Success ◽  
Technical Success Rate ◽  
Expandable Metallic Stent ◽  
Increased Risk

Abstract Background and aim To assess the rate of adverse events and the technical success rate of biliary stenting with or without EBS.  Methods A literature search up to February 2017 was performed. Studies assessing adverse events (AEs) and technical success rates of stenting with or without EBS were considered. Results Seven studies (870 patients; 12 treatment arms) were included. Early AEs, i. e. those occurring within 30 days, were significantly lower in no-EBS vs. EBS-group (11 % vs. 20.1 %; OR: 0.36, 95 %CI: 0.13 – 1.00). Rates of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis were not significantly different in the two groups (no-EBS vs. EBS: 6.1 % vs 5 %; OR: 1.33, 95 %CI: 0.68 – 2.59). The rate of bleeding was significantly lower in patients without EBS (no-EBS vs EBS: 0 % vs 5 %; OR: 0.12, 95 % CI: 0.03 – 0.45). Rates of cholangitis were significantly lower in patients without EBS (no-EBS vs. EBS: 3.3 % vs. 7.4 %; OR: 0.38, 95 %CI: 0.17 – 0.83). Both late AEs and mortality rates did not significantly differ between no-EBS and EBS patients (19.9 % vs. 18.9 %; OR: 0.93, 95 %CI: 0.56 – 1.53, and 2.5 % vs. 2.9 %; OR: 1.18, 95 %CI: 0.22 – 6.29, respectively). The technical success rate for stent insertion also did not differ (98 % vs. 97.6 %; OR: 1.05, 95 %CI: 0.42 – 2.63). Conclusion EBS seems to be associated, in the first 30 days after the procedure, with an increased risk of cholangitis and bleeding. No difference was observed in the rate of post-ERCP pancreatitis.

scholarly journals Successful Stent-in-stent Insertion of an Expandable Metallic Stent Covered with Polyuretane Placed to Obliterate a Large Bronchial Fistula after Chemoradiotherapy for Inoperable Lung Cancer.

Haigan ◽  
1999 ◽  
Vol 39 (6) ◽  
pp. 877-880
Author(s):  
Hiroya Minami ◽  
Noriaki Tsubota ◽  
Yoshifumi Miyamoto ◽  
Masahiro Yoshimura ◽  
Kayoko Obayashi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Stent Insertion ◽  
Metallic Stent ◽  
Bronchial Fistula ◽  
Expandable Metallic Stent

Early Infectious Complications of Percutaneous Metallic Stent Insertion for Malignant Biliary Obstruction

2010 ◽  
Vol 194 (1) ◽  
pp. 261-265 ◽  
Author(s):  
Yu Li Sol ◽  
Chang Won Kim ◽  
Ung Bae Jeon ◽  
Nam Kyung Lee ◽  
Suk Kim ◽  
...  
Keyword(s):  
Biliary Obstruction ◽  
Infectious Complications ◽  
Malignant Biliary Obstruction ◽  
Stent Insertion ◽  
Metallic Stent

scholarly journals Antibiotic Prophylaxis in Transarterial Therapy of Hepatocellular Carcinoma: A Meta-Analysis

2012 ◽  
Vol 26 (2) ◽  
pp. 85-91 ◽  
Author(s):  
Jun Wang ◽  
Xiao Dong He ◽  
You Cheng Zhang
Keyword(s):  
Hepatocellular Carcinoma ◽  
Antibiotic Prophylaxis ◽  
Antibiotic Treatment ◽  
Meta Analysis ◽  
Survival Rates ◽  
Prophylactic Antibiotic ◽  
Infectious Complications ◽  
Bibliographic Databases ◽  
Increased Risk ◽  
Prophylactic Antibiotic Treatment

Transarterial therapies, either alone or in conjunction with adjuvant therapies, have been demonstrated to improve survival rates in patients with hepatocellular carcinoma (HCC). Although generally well tolerated and widely used for more than two decades, transarterial procedures have been reported to be associated with several infectious complications when performed in patients with HCC. However, the question of whether antibiotic prophylaxis is necessary for patients undergoing transarterial procedures for HCC remains controversial. Accordingly, this meta-analysis examined clinical trial evidence regarding the effects of prophylactic antibiotic therapy versus no prophylactic treatment with respect to infectious complications in patients undergoing transarterial therapy for HCC.BACKGROUND: The use of prophylactic antibiotics against postprocedure infection in patients undergoing transarterial therapy for hepatocellular carcinoma is controversial.AIM: To compare the effects of prophylactic antibiotic treatment and no prophylactic antibiotic treatment on infectious complications following transarterial procedures.METHODS: Clinical trials fulfilling predefined selection criteria were identified by searching several bibliographic databases; a meta-analysis was performed where appropriate.RESULTS: Four trials of inadequate quality consisting of 210 patients were included in the analysis. Only one case of possible postprocedure infection in each group was reported. The rate of patients developing fever (RR 0.91 [95% CI 0.61 to 1.35]), changes in peripheral white blood cell count or serum C-reactive protein levels, and the mean length of hospital stay (mean difference 0.20 [95% CI 0.75 to 1.14]) showed no significant intergroup differences between antibiotic and no antibiotic treatment. Furthermore, the results of the present study indicated that the incidence of bacteremia, septicemia, sepsis or hepatic abscess after transarterial therapy was rare.CONCLUSION: Antibiotic prophylaxis in patients undergoing transarterial therapy for hepatocellular carcinoma may not be routinely necessary. However, a more judicious use of antibiotics is recommended for patients who are at an increased risk of infection. Nevertheless, prospective trials on a larger scale are clearly needed.

scholarly journals Current therapies in treatment and prevention of fracture wound biofilms: why a multifaceted approach is essential for resolving persistent infections

2018 ◽  
Vol 3 (2) ◽  
pp. 50-67 ◽  
Author(s):  
Krystle A. Blanchette ◽  
Joseph C. Wenke
Keyword(s):  
Bacterial Infections ◽  
Prophylactic Antibiotic ◽  
Infectious Complications ◽  
Persistent Infections ◽  
Treatment And Prevention ◽  
Current Therapies ◽  
Prophylactic Antibiotic Treatment ◽  
Orthopedic Injuries ◽  
Experimental Treatments ◽  
Wound Biofilms

Abstract. Traumatic orthopedic injuries, particularly extremity wounds, are a significant cause of morbidity. Despite prophylactic antibiotic treatment and surgical intervention, persistent infectious complications can and do occur. Persistent bacterial infections are often caused by biofilms, communities of antibiotic tolerant bacteria encased within a matrix. The structural and metabolic differences in this mode of growth make treatment difficult. Herein, we describe both established and novel, experimental treatments targeted at various stages of wound healing that are specifically aimed at reducing and eliminating biofilm bacteria. Importantly, the highly tolerant nature of these bacterial communities suggests that most singular approaches could be circumvented and a multifaceted, combinatorial approach will be the most effective strategy for treating these complicated infections.

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