scholarly journals Prolonged P-Wave and QT Dispersion in Children with Inflammatory Bowel Disease in Remission

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Helen Aghdasi Bornaun ◽  
Nuh Yılmaz ◽  
Günsel Kutluk ◽  
Reyhan Dedeoğlu ◽  
Kazım Öztarhan ◽  
...  

Objectives.Ulcerative colitis (UC) and Crohn’s disease (CD) are chronic inflammatory bowel diseases (IBD) with unclear underlying aetiologies. Severe cardiac arrhythmias have been emphasised in a few studies on adult IBD patients. This study aimed to investigate the alteration of the P-wave and QT interval dispersion parameters to assess the risk of atrial conduction and ventricular repolarisation abnormalities in pediatric IBD patients.Patients and Methods.Thirty-six IBD patients in remission (UC: 20, CD: 16) aged 3–18 years and 36 age- and sex-matched control patients were enrolled in the study. Twelve-lead electrocardiograms were used to determine durations of P-wave, QT, and corrected QT (QTc) interval dispersion. Transthoracic echocardiograms and 24-hour rhythm Holter recordings were obtained for both groups.Results.The P-wave dispersion, QT dispersion, and QTc interval dispersion (Pdisp, QTdisp, and QTcdisp) were significantly longer in the patient group. The mean values of Pminimum, Pmaximum, and QTcminimum were significantly different between the two groups. The echocardiography and Holter monitoring results were not significantly different between the groups. Furthermore, no differences in these parameters were detected between the CD and UC groups.Conclusion.Results suggest that paediatric IBD patients may carry potential risks for serious atrial and ventricular arrhythmias over time even during remission.

2014 ◽  
Vol 11 (11) ◽  
pp. 1140-1146 ◽  
Author(s):  
Arnd Giese ◽  
Ahmet Örnek ◽  
Mustafa Kurucay ◽  
Kaffer Kara ◽  
Helmut Wittkowski ◽  
...  

2019 ◽  
Vol 29 (4) ◽  
pp. 488-491
Author(s):  
Oyku Tosun ◽  
Elif Karatoprak

AbstractIntroduction:Migraine is a common neurovascular disease characterised with recurrent attacks by pain-free periods. It has been suggested that both sympathetic and parasympathetic dysfunctions play a role in its pathophysiology.Aim:The aim of our study was to investigate the ECG changes during attack-free period in children with migraine, in terms of QTc interval, QTc, and P-wave dispersion to evaluate the autonomic nervous system disturbance.Methods:Sixty children who were diagnosed with migraine were included as patient group and 50 healthy, age- and body mass index-matched children who were examined for innocent murmur were included as control group. The patients’ routine ECG records were screened from the outpatient clinic files. The durations of P-wave, QT, and QTc intervals and dispersion values and heart rates (beats/minute) were compared between the patient and control groups.Results:P maximum and P dispersion were significantly higher, and P minimum was significantly lower in the migraine group compared with the control group. QT–QTc maximum and QT–QTc dispersion were significantly higher and QT–QTc minimum was significantly lower in the migraine group compared with the control group.Conclusion:According to our findings, although migraine patients were asymptomatic and no arrhythmia was detected in the surface ECG, sympathovagal balance in the sympathetic system, which may be disrupted in favour of the sympathetic system, should continue even in the attack-free period, and we should be careful in terms of serious arrhythmias that may develop in these patients.


2020 ◽  
Vol 30 (11) ◽  
pp. 1666-1671
Author(s):  
Tulay Demircan ◽  
Zuhal Onder Sivis ◽  
Burçak Tatlı Güneş ◽  
Cem Karadeniz

AbstractIron overload is associated with an increased risk of atrial and ventricular arrhythmias. Data regarding the relationship between electrocardiographic parameters of atrial depolarisation and ventricular repolarisation with cardiac T2* MRI are scarce. Therefore, we aimed to investigate these electrocardiographic parameters and their relationship with cardiac T2* value in patients with β-thalassemia major. In this prospective study, 52 patients with β-thalassemia major and 52 age- and gender-matched healthy patients were included. Electrocardiographic measurements of QT, T peak to end interval, and P wave intervals were performed by one cardiologist who was blind to patients’ data. All patients underwent MRI for cardiac T2* evaluation. Cardiac T2* scores less than 20 ms were considered as iron overload. P wave dispersion, QTc interval, and the dispersions of QT and QTc were significantly prolonged in β-thalassemia major patients compared to controls. Interestingly, we found prolonged P waves, QT and T peak to end dispersions, T peak to end intervals, and increased T peak to end/QT ratios in patients with T2* greater than 20 ms. No significant correlation was observed between electrocardiographic parameters and cardiac T2* values and plasma ferritin levels. In conclusion, our study demonstrated that atrial depolarisation and ventricular repolarisation parameters are affected in β-thalassemia major patients and that these parameters are not correlated with cardiac iron load.


2017 ◽  
Vol 3 (4) ◽  
pp. 165-168 ◽  
Author(s):  
Servet Yolbas ◽  
Ahmet Yildirim ◽  
Deccane Duzenci ◽  
Bulent Karakaya ◽  
Mustafa Necati Dagli ◽  
...  

Cor et Vasa ◽  
2019 ◽  
Vol 61 (5) ◽  
pp. 459-463
Author(s):  
Habibe Kafes ◽  
Burak Açar ◽  
Lale Asarcikli ◽  
Esra Gucuk ◽  
Zeki Mesut Yalin Kilic ◽  
...  

2012 ◽  
Vol 12 (04) ◽  
pp. 1240016
Author(s):  
V. KALPANA ◽  
S. T. HAMDE ◽  
L. M. WAGHMARE

Electrocardiography deals with the electrical activity of the heart. The condition of cardiac health is given by the electrocardiogram (ECG). ECG analysis is one of the most important aspects of research in the field of biomedical sciences and healthcare. The precision in the identification of various parameters in the ECG is of great importance for the reliability of an automated ECG analyzing system and diagnosis of cardiac diseases. Many algorithms have been developed in the last few years, each with their own advantages and limitations. In this work, we have developed an algorithm for 12-lead ECG parameter detection which works in three steps. Initially, the signal is denoised by the wavelet transform approach using a graphical programming language called LabVIEW (Laboratory Virtual Instrument Engineering Workbench). Next, primary features are detected from the denoised ECG signal using Matlab, and lastly, the secondary features related to diabetes are estimated from the detected primary features. Diabetes mellitus (DM), which is characterized by raised blood glucose levels in an individual, affects an estimated 2–4% of the world's population, making it one of the major chronic illnesses prevailing today. Recently, there has been increasing interest in the study of relationship between diabetes and cardiac health. Thus, in this work, we estimate diabetic-related secondary ECG features like corrected QT interval (QTc), QT dispersion (QTd), P wave dispersion (PD), and ST depression (STd). Our software performance is evaluated using CSE DS-3 multi-lead data base and the data acquired at SGGS IE & T, Nanded, MS, which contains 5000 samples recorded at a sampling frequency of 500 HZ. The proposed algorithm gives a sensitivity of 99.75% and a specificity of 99.83%.


2006 ◽  
Vol 30 (6) ◽  
pp. 957-961 ◽  
Author(s):  
E Seyfeli ◽  
M Duru ◽  
G Kuvandık ◽  
H Kaya ◽  
F Yalcin

Sign in / Sign up

Export Citation Format

Share Document