Papillary Fibroelastoma as a Cause of Cardiogenic Embolic Stroke in aβ-Thalassemia Patient: Case Report and Literature Review

We describe a case of a young male without stroke risk factors who presented with a sudden onset of left-sided weakness, left hand numbness, and left eye blurriness. CT scan of the head without contrast and diffusion-weighted MRI of the brain with contrast revealed an ischemic stroke in the right middle cerebral artery distribution. Transesophageal echocardiography (TEE) revealed a mobile pedunculated mass on the posterior surface of the mitral valve. This mass was resected and pathology showed a cardiac papillary fibroelastoma (CPFE), which was determined to be the cause of the patient’s cardioembolic stroke. Further workup also found that patient had microcytic anemia secondary toβ-thalassemia intermedia, a rare hematologic disorder due to defective hemoglobin synthesis. Recently, another case report suggestedβ-thalassemia major may underlie the pathogenesis of CPFE.β-Thalassemia major causes a state of chronic inflammation and endothelial damage, which can mediate CPFE formation. Based on literature review, this is the first case report of a CPFE in a patient withβ-thalassemia intermedia. This hypothesis-generating case report calls attention to the need for elucidating the relationship between CPFE andβ-thalassemia in future studies to better understand the diagnosis and management of a rare cardiac tumor.

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Anosmia, a Hidden Sign for COVID-19? A Case Report and Literature Review

10.21203/rs.3.rs-27117/v1 ◽

2020 ◽

Author(s):

Karen Christelle ◽

Maryam Mohd Zulkifli ◽

Nani Draman

Keyword(s):

Case Report ◽

Literature Review ◽

Close Contact ◽

Relevant Literature ◽

Sudden Onset ◽

World Health ◽

Mass Gatherings ◽

First Case ◽

Control And Prevention ◽

History Of

Abstract Background The coronavirus disease 2019 (COVID-19) is an ongoing viral pandemic that is actively affecting 210 countries worldwide, with a total of more than 1.5 million cases and 106 000 deaths. Symptoms associated with COVID-19 are mainly fever, cough, dyspnea and sore throat. The current indication for COVID-19 testing includes presence of these symptoms with a positive history of travel to affected countries or contact with COVID-19 patients. Anosmia has been recently reported anecdotally over the past weeks as an emerging symptom of the COVID-19 but has yet to gain recognition as a symptom for COVID-19 by the World Health Organization (WHO) and Centre for Disease Control and Prevention (CDC). This case report highlights a case of isolated sudden onset of anosmia as a presenting symptom of COVID-19 and relevant literature review supporting the incidence of anosmia in COVID-19. This is a first case report of anosmia in COVID-19 occurring in pregnancy.Case Presentation A 30-year-old pregnant lady at 11 weeks of gestation presented with sudden onset of anosmia for one day with no other accompanying symptoms. She had just recovered from a mild cold a day prior to the development of anosmia. She had a history of travel by land to Singapore 14 days prior to onset of anosmia. There was no known close contact with a COVID-19 patient or attended any mass gatherings prior to development of her symptom. She underwent nasopharyngeal and oropharyngeal swab sampling which was then tested using reverse transcription polymerase chain reaction (RT-PCR) method and confirmed infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).Conclusion Clinicians should be aware regarding anosmia as a presenting symptom of COVID-19 especially in the presence of risk factors such as travel to affected countries and having close contact with COVID-19 positive patients. If testing is not done, these patients should be advised for home quarantine to reduce the risk of transmission. Healthcare workers must always adhere to infection control and prevention protocol as well as personal protective equipment.

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The first case report of Haim Munk disease with neurological manifestations and literature review

Clinical Case Reports ◽

10.1002/ccr3.4802 ◽

2021 ◽

Vol 9 (9) ◽

Author(s):

Mehdi Moghaddasi ◽

Mohammadreza Ghassemi ◽

Mohammad Shekari Yazdi ◽

Seyed Amir Hasan Habibi ◽

Nafiseh Mohebi ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Neurological Manifestations ◽

First Case

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The first reported treatment of Nager syndrome associated hearing loss with bone-anchored hearing aids: case report

The Journal of Laryngology & Otology ◽

10.1017/s0022215111002738 ◽

2011 ◽

Vol 126 (1) ◽

pp. 76-78 ◽

Cited By ~ 4

Author(s):

G P Davies ◽

I J M Johnson

Keyword(s):

Hearing Loss ◽

Case Report ◽

Literature Review ◽

Current Literature ◽

Hearing Aids ◽

Clinical Case ◽

Conductive Hearing Loss ◽

First Case ◽

Nager Syndrome ◽

Conductive Hearing

AbstractObjective:To report the first case of treatment of Nager syndrome associated conductive hearing loss with bone-anchored hearing aids, in a three-year-old boy.Method:Clinical case report and current literature review regarding the use of bone-anchored hearing aids in the treatment of conductive hearing loss in children.Results:A three year eight month old boy with Nager syndrome was successfully treated for conductive hearing loss using bilateral bone-anchored hearing aids.Conclusion:This is the first case report of the use of bone-anchored hearing aids to treat Nager syndrome associated conductive hearing loss. Treatment was safe and successful in this case.

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Sepsis Caused by Bacterial Colonization of Migrated Distal Ventriculoperitoneal Shunt Catheter into the Pulmonary Artery: A First Case Report and Literature Review

World Neurosurgery ◽

10.1016/j.wneu.2019.02.176 ◽

2019 ◽

Vol 126 ◽

pp. 172-180 ◽

Cited By ~ 1

Author(s):

Edin Hajdarpašić ◽

Almir Džurlić ◽

Nevena Mahmutbegović ◽

Salko Zahirović ◽

Adi Ahmetspahić ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Pulmonary Artery ◽

Ventriculoperitoneal Shunt ◽

Bacterial Colonization ◽

Shunt Catheter ◽

First Case

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High-Altitude Decompression Sickness Treated with Hyperbaric Therapy and Extracorporeal Oxygenation

Aerospace Medicine and Human Performance ◽

10.3357/amhp.5457.2020 ◽

2020 ◽

Vol 91 (2) ◽

pp. 106-109

Author(s):

Jacek Siewiera ◽

Przemysław Szałański ◽

Dariusz Tomaszewski ◽

Jacek Kot

Keyword(s):

Case Report ◽

High Altitude ◽

Decompression Sickness ◽

Endothelial Damage ◽

Neurological Deficits ◽

Institute Of Medicine ◽

First Case ◽

Hyperbaric Therapy ◽

Extracorporeal Oxygenation ◽

Vv Ecmo

BACKGROUND: High-altitude decompression sickness (HADCS) is a rare condition that has been associated with aircraft accidents. To the best of our knowledge, the present paper is the first case report of a patient treated for severe HADCS using recompression therapy and veno-venous extracorporeal oxygenation (VV-ECMO) with a complete recovery.CASE REPORT: After depressurization of a cabin, the 51-yr-old jet pilot was admitted to the Military Institute of Medicine with a life-threatening HADCS approximately 6 h after landing from a high-altitude flight, in a dynamically deteriorating condition, with progressing dyspnea and edema, reporting increasing limb paresthesia, fluctuating consciousness, and right-sided paresis. Hyperbaric oxygen therapy in the intensive care mode was initiated. A therapeutic recompression with U.S. Navy Treatment Table 6 was performed with neurological improvement. Due to cardiovascular collapse, sedation, mechanical ventilation, and significant doses of catecholamines were started, followed by continuous veno-venous hemodialysis. In the face of disturbances in oxygenation, during the second day of treatment the patient was commenced on veno-venous extracorporeal oxygenation. Over the next 6 d, the patient’s condition slowly improved. On day 7, VV-ECMO was discontinued. On day 19, the patient was discharged with no neurological deficits.DISCUSSION: We observed two distinct stages during the acute phase of the disease. During the first stage, signs of hypoperfusion, neurological symptoms, and marbled skin were observed. During the second stage, multiple organ dysfunction dominated, including heart failure, pulmonary edema, acute kidney injury, and fluid overload, all of which can be attributed to extensive endothelial damage.Siewiera J, Szałański P, Tomaszewski D, Kot J. High-altitude decompression sickness treated with hyperbaric therapy and extracorporeal oxygenation. Aerosp Med Hum Perform. 2020; 91(2):106–109.

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Inflammatory Myofibroblastic Tumor of the Epiglottis Excised with a Carbon Dioxide Laser: Case Report and Literature Review

Ear Nose & Throat Journal ◽

10.1177/014556131809700806 ◽

2018 ◽

Vol 97 (8) ◽

pp. E31-E33 ◽

Cited By ~ 1

Author(s):

Blake Raggio ◽

Neil Chheda

Keyword(s):

Carbon Dioxide ◽

Case Report ◽

Adjuvant Therapy ◽

Literature Review ◽

Carbon Dioxide Laser ◽

Inflammatory Myofibroblastic Tumor ◽

Benign Neoplasm ◽

First Case ◽

Laser Excision

Inflammatory myofibroblastic tumor (IMT) is a benign neoplasm of intermediate biologic potential. It rarely occurs in the larynx, and it has not been previously reported in the epiglottis. We treated a 66-year-old woman who presented with progressive dysphonia and a mass on her suprahyoid epiglottis. The tumor was completely excised with a CO2 laser; no adjuvant therapy was administered. Histopathology revealed that the mass was an IMT. No evidence of recurrence was noted after 6 months of follow-up. We present what we believe is the first case of an epiglottic IMT to be reported in the literature, and we propose CO2 laser excision without adjuvant therapy as an acceptable treatment.

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A First Case of Acute Cerebellitis Associated with Coronavirus Disease (COVID-19): a Case Report and Literature Review

The Cerebellum ◽

10.1007/s12311-020-01177-9 ◽

2020 ◽

Vol 19 (6) ◽

pp. 911-914 ◽

Cited By ~ 2

Author(s):

Nima Fadakar ◽

Sara Ghaemmaghami ◽

Seyed Masoom Masoompour ◽

Babak Shirazi Yeganeh ◽

Ali Akbari ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Acute Cerebellitis ◽

First Case

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Dissecting basilar artery aneurysm manifesting as sudden sensorineural hearing loss: a case report and literature review

Journal of International Medical Research ◽

10.1177/0300060519875374 ◽

2019 ◽

Vol 47 (11) ◽

pp. 5844-5848

Author(s):

Yi-zhi Zhang ◽

Qiu-hui Chen ◽

Zhan-chuan Liu ◽

Ying Zhang ◽

Yan-qiu Han ◽

...

Keyword(s):

Hearing Loss ◽

Case Report ◽

Literature Review ◽

Sensorineural Hearing Loss ◽

Basilar Artery ◽

Artery Aneurysm ◽

Sudden Sensorineural Hearing Loss ◽

Sensorineural Hearing ◽

First Case ◽

Basilar Artery Aneurysm

Highlights • Dissecting basilar artery aneurysm (DBAA) is relatively rare. • We report the first case of a DBAA manifesting as sudden sensorineural hearing loss. • This case report adds to the symptom spectrum of DBAA.

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