scholarly journals Optimization of Hydrothermal and Diluted Acid Pretreatments of Tunisian Luffa cylindrica (L.) Fibers for 2G Bioethanol Production through the Cubic Central Composite Experimental Design CCD: Response Surface Methodology

2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Kaouther Zaafouri ◽  
Manel Ziadi ◽  
Aida Ben Hassen-Trabelsi ◽  
Sabrine Mekni ◽  
Balkiss Aïssi ◽  
...  
Keyword(s):  
Experimental Design ◽  
Alcoholic Fermentation ◽  
Reducing Sugars ◽  
Enzymatic Saccharification ◽  
Hydrothermal Pretreatment ◽  
Luffa Cylindrica ◽  
Central Composite Experimental Design ◽  
Central Composite ◽  
Volumetric Yield

This paper opens up a new issue dealing with Luffa cylindrica (LC) lignocellulosic biomass recovery in order to produce 2G bioethanol. LC fibers are composed of three principal fractions, namely, α-cellulose (45.80%  ± 1.3), hemicelluloses (20.76%  ± 0.3), and lignins (13.15%  ± 0.6). The optimization of LC fibers hydrothermal and diluted acid pretreatments duration and temperature were achieved through the cubic central composite experimental design CCD. The pretreatments optimization was monitored via the determination of reducing sugars. Then, the 2G bioethanol process feasibility was tested by means of three successive steps, namely, LC fibers hydrothermal pretreatment performed at 96°C during 54 minutes, enzymatic saccharification carried out by means of a commercial enzyme AP2, and the alcoholic fermentation fulfilled with Saccharomyces cerevisiae. LC fibers hydrothermal pretreatment liberated 33.55 g/kg of reducing sugars. Enzymatic hydrolysis allowed achieving 59.4 g/kg of reducing sugars. The conversion yield of reducing sugar to ethanol was 88.66%. After the distillation step, concentration of ethanol was 1.58% with a volumetric yield about 70%.

Supramolecular solvent-based microextraction method for cobalt traces in food samples with optimization Plackett–Burman and central composite experimental design

RSC Advances ◽  
2015 ◽  
Vol 5 (115) ◽  
pp. 94879-94886 ◽  
Author(s):  
Funda Aydin ◽  
Erkan Yilmaz ◽  
Mustafa Soylak
Keyword(s):  
Experimental Design ◽  
Atomic Absorption Spectrometry ◽  
Flame Atomic Absorption Spectrometry ◽  
Absorption Spectrometry ◽  
Optimization Method ◽  
Food Samples ◽  
Flame Atomic Absorption ◽  
Supramolecular Solvent ◽  
Central Composite Experimental Design ◽  
Central Composite

A new microextraction method based on formation of supramolecular solvent (Ss) was developed by using of chemometric optimization method for cobalt determination with microsampling flame atomic absorption spectrometry (MS-FAAS).

Evaluation of methyl chavicol concentration by different evaporation processes using central composite experimental design

2012 ◽  
Vol 98 ◽  
pp. 464-471 ◽  
Author(s):  
Patricia Fazzio Martins ◽  
Claudio Carmona ◽  
Edgar Leonardo Martinez ◽  
Paula Sbaite ◽  
Rubens Maciel Filho ◽  
...  
Keyword(s):  
Experimental Design ◽  
Methyl Chavicol ◽  
Central Composite Experimental Design ◽  
Central Composite

Central Composite experimental design applied to removal of lead and nickel from sand

2009 ◽  
Vol 172 (2-3) ◽  
pp. 1087-1092 ◽  
Author(s):  
V.V. Guaracho ◽  
N.M.S. Kaminari ◽  
M.J.J.S. Ponte ◽  
H.A. Ponte
Keyword(s):  
Experimental Design ◽  
Central Composite Experimental Design ◽  
Central Composite

scholarly journals Optimization by Central Composite Experimental Design of the Synthesis of Physically Crosslinked Chitosan Spheres

Biomimetics ◽  
2020 ◽  
Vol 5 (4) ◽  
pp. 63
Author(s):  
Sara Isabel Zamora Lagos ◽  
Jefferson Murillo Salas ◽  
Mayra Eliana Valencia Zapata ◽  
José Herminsul Mina Hernández ◽  
Carlos David Grande Tovar
Keyword(s):  
Tissue Engineering ◽  
Experimental Design ◽  
Biological Properties ◽  
Sphere Diameter ◽  
Naoh Solution ◽  
Central Composite Experimental Design ◽  
Physically Crosslinked ◽  
Needle Diameter ◽  
Central Composite ◽  
Crosslinking Agents

Chitosan (CS) has special properties such as biocompatibility, biodegradability, antibacterial, and biological activity which make this material is currently studied in various applications, including tissue engineering. There are different methods to modify the morphology of CS. Most use chemical crosslinking agents, however, those methods have disadvantages such as low polymer degradability and unwanted side effects. The objective of this research was to obtain CS spheres through the physical crosslinking of commercial CS without using crosslinking agents through a simple coacervation method. A central composite experimental design was used to optimize the synthesis of the CS spheres and by the response surface methodology it was possible to obtain CS spheres with the smallest diameter and the most regular morphology. With the optimal formulation (CS solution 1.8% (w/v), acetic acid (AAC) solution 1% (w/v), sodium hydroxide (NaOH) solution 13% (w/v), relative humidity of (10%) and needle diameter of 0.6 mm), a final sphere diameter of 1 mm was obtained. Spheres were characterized by physical, chemical, thermal, and biological properties in simulated body fluid (SBF). The results obtained allowed us to understand the effect of the studied variables on the spheres’ diameter. An optimized condition facilitated the change in the morphology of the CS while maintaining its desirable properties for use in tissue engineering.

Optimization of the indole photodegradation on supported TiO2: influences of temperature, concentration, TiO2 amount and flow rate

2008 ◽  
Vol 58 (3) ◽  
pp. 549-554 ◽  
Author(s):  
Smail Merabet ◽  
Michel Schneider ◽  
Didier Robert ◽  
Smail Benkhanouche ◽  
Mohammed Bouhelassa ◽  
...  
Keyword(s):  
Experimental Design ◽  
Flow Rate ◽  
Cellulose Fibres ◽  
Complete Degradation ◽  
Central Composite Experimental Design ◽  
Supported Tio2 ◽  
Central Composite

This work describes the photodegradation of aqueous indole solutions by using TiO2 supported on cellulose fibres. Four parameters were studied: the indole concentration; the TiO2 amount; the temperature and the flow rate. Central composite experimental design was used to determine the influences of the parameters on the indole degradation percentage. We demonstrate that in our experimental domain the quasi complete degradation of indole is in all cases reached and more interestingly that it is possible to find unique values of TiO2 amount and flow rate leading to optimised photodegradation of indole in the studied domains of temperature and indole concentration.

Automated development of a kinetic method for the continuous-flow determination of creatinine.

1978 ◽  
Vol 24 (12) ◽  
pp. 2115-2124 ◽  
Author(s):  
A S Olansky ◽  
S N Deming
Keyword(s):  
Continuous Flow ◽  
Clinical Chemistry ◽  
Kinetic Method ◽  
Chemistry Laboratory ◽  
Chemical Methods ◽  
Central Composite Experimental Design ◽  
Clinical Chemistry Laboratory ◽  
Computer Controlled ◽  
Central Composite

Abstract A "stopped-flow" method for the kinetic Jaffé determination of creatinine was developed, with the use of a computer-controlled continuous-flow system. Simplex optimization was used to find conditions of hydroxide and picrate giving maximum sensitivity for creatinine. We used a modified central composite experimental design to evaluate creatinine sensitivity and albumin, glucose, and acetone interferences as functions of hydroxide and picrate concentrations. More importantly, this work illustrates that the automated development of clinical chemical methods offers an efficient means of obtaining optimized, well-understood analytical procedures for subsequent routine use in the clinical chemistry laboratory.

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