scholarly journals Change of Anesthesia Management for a Patient Undergoing CABG by an Incidental Finding of a Genetic Variant Associated with Malignant Hyperthermia

2019 ◽  
Vol 2019 ◽  
pp. 1-3 ◽  
Author(s):  
Trey B. Creech ◽  
Li Zhang
Keyword(s):  
Malignant Hyperthermia ◽  
Coronary Artery Bypass Surgery ◽  
Genetic Variant ◽  
Incidental Finding ◽  
Artery Bypass ◽  
Anesthesia Management ◽  
Anesthesia Providers ◽  
Whole Exome ◽  
Life Threatening ◽  
History Of

Malignant hyperthermia (MH) is a rare life-threatening hypermetabolic muscular disorder with a high mortality rate. Three genes, RYR1, CACNA1S, and STAC3, have been associated with MH susceptibility. Multiple genetic variants have been identified in these three genes. Some of those variants were pathogenic, but many others are yet to be tested. Such uncertainty can make it challenging for anesthesia providers as there is currently no anesthesia guideline for each genetic variant in patients who have neither clinical nor family history of MH. With the increasing popularity of whole exome sequencing, anesthesia providers will likely face such challenges more often as many patients may have genetic variations of unknown clinical significance in their RYR1, CACNA1S, or STAC3 genes. Here we describe change of anesthesia management for a patient who had an incidental finding of a genetic variant in RYR1 gene undergoing an elective coronary artery bypass surgery.

scholarly journals Development of Multiple Aortic Mycotic Aneurysms After Cardiac Catheterization

2017 ◽  
Vol 5 (4) ◽  
pp. 232470961774090
Author(s):  
Desiree A. Steimer ◽  
John J. Squiers ◽  
J. Michael DiMaio ◽  
Katherine B. Harrington
Keyword(s):  
Cardiac Catheterization ◽  
Aortic Root ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Ascending Aorta ◽  
Aortic Root Replacement ◽  
Past Medical History ◽  
History Of ◽  
Mycotic Aneurysms

A 71-year-old male with a past medical history of coronary artery bypass surgery developed multiple, infected pseudoaneurysms of the ascending aorta and aortic root 1 year after cardiac catheterization. He underwent aortic root replacement with a 24-mm homograft. Tissue culture from operative specimens revealed invasive Aspergillus fumigatus infection. He was treated with voriconazole for 3 months. After 1 year, he had no recurrence of symptoms, pseudoaneurysm, or fungal infection.

TO THE QUESTION ABOUT SPECIFIC FEATURES OF THE CARDIOVASCULAR RISK FACTORS STRUCTURE IN MEN UNDER 60 YEARS OLD WITH ACUTE KIDNEY INJURY DURING MYOCARDIAL INFARCTION

2021 ◽  
pp. 23-28
Author(s):  
Gordienko A.V. ◽  
Balabanov A.S. ◽  
Tassybayev B.B.
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Kidney Injury ◽  
Study Group ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
History Of

Relevance. Acute kidney injury (AKI) worsens the prognosis of myocardial infarction (MI). Aim. To study the characteristics of cardiovascular (CVD) risk factors in men under 60 years of age with AKI in myocardial infarction (MI) to improve prevention. Material and methods. The study included men aged 19-60 years old with type I MI. Patients are divided into two age-comparable groups: I - the study group, with ACI - 25 patients; II - control, without it - 168 patients. A comparative analysis of the frequency of observation of the main and additional CVD risk factors in groups was performed. Results. In the patients of the study group, more often than in the control group, the following was observed: MI in winter (68.0 and 36.3%, respectively; p = 0.01), with repeated cases - the interval between infarction of more than one year (48.0 and 29.8%; p = 0.04); psychoemotional stress (64.0 and 46.1%; p = 0.04) or hypertensive crisis as a situation provoking MI (28.0 and 19.2%; p = 0.04); a history of: overweight less than 10 years (72.0 and 35.7%; p = 0.002) with moderate obesity (48.0 and 22.6%; p = 0.03), chronic heart failure (36.0 and 14.0%; p = 0.006), peptic ulcer (32.0 and 13.7%; p = 0.01), unstable angina (64.0 and 42.6%; p = 0.003), peripheral angiopathies (80.0 and 56.5%; p = 0.02), coronary angiography (45.5 and 25.5%; p = 0.04) and coronary artery bypass surgery (24.0 and 8.6%; p = 0.009). Conclusions. The structure of CVD risk factors in men under 60 years old with MI and AKI is characterized by the prevalence of moderate obesity, gastroduodenal ulcers, chronic heart failure, stress and crisis course of hypertension, coronary angiography and a history of coronary artery bypass surgery, as well as MI in winter. It is advisable to use the listed combinations of factors in predictive modeling and planning of preventive measures in such patients.

The Current Status of Anastomotic Devices for Coronary Artery Bypass Surgery

2009 ◽  
Vol 4 (1) ◽  
pp. 9-12 ◽  
Author(s):  
John D. Puskas
Keyword(s):  
Coronary Artery ◽  
Clinical Outcome ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Outcome Data ◽  
Current Status ◽  
Proximal Anastomosis ◽  
History Of ◽  
Anastomotic Devices

The purpose of this article is to briefly review the history of proximal and distal anastomotic devices and to discuss presently available devices. Clinical outcome data from the EPIC Trial of the Cardica PAS-Port Proximal Anastomosis System will also be presented.

scholarly journals Lipomatous Hypertrophy of the Atrial Septum in a Patient Undergoing Coronary Artery Bypass Surgery

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Thomas Strecker ◽  
Michael Weyand ◽  
Abbas Agaimy
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Artery Bypass ◽  
Cardiovascular Complications ◽  
Atrial Septum ◽  
Fatty Tissue ◽  
Life Threatening ◽  
Lipomatous Hypertrophy

Background. Lipomatous hypertrophy of the atrial septum (LHAS) is a rare entity characterized by mass-forming deposition of fatty tissue within the atrial septum. To date, <300 cases have been reported; many of them were autopsy findings. The clinical presentation of LHAS varies from incidental asymptomatic mass (most frequent form) to severe life-threatening cardiovascular complications necessitating emergency cardiac surgery. Case Presentation. Here, we present the successful surgical resection of such a massive LHAS which was found incidentally on preoperative investigation of a 71-year-old patient with progressive coronary heart disease. Histology confirmed the diagnosis of lipomatous hypertrophy of the atrial septum. Conclusions. The described case report illustrates an unusual example of LHAS in a patient undergoing a planned coronary artery bypass surgery. In this case, surgical intervention was justified to avoid later outflow obstructions.

scholarly journals Catheter ablation of incessant monomorphic ventricular tachycardia complicating the post-operative period after coronary artery bypass grafting

2020 ◽  
Vol 4 (Issue 4) ◽  
Author(s):  
Panagiotis Koudounis ◽  
Maria Agelaki ◽  
Apostolos Christou ◽  
Vaia Magaliou ◽  
Paraskevi Fragkou ◽  
...  
Keyword(s):  
Ventricular Tachycardia ◽  
Coronary Artery ◽  
Catheter Ablation ◽  
Coronary Artery Bypass ◽  
Coronary Artery Bypass Surgery ◽  
Bypass Surgery ◽  
Electrophysiological Study ◽  
Artery Bypass ◽  
Monomorphic Ventricular Tachycardia ◽  
History Of

A 68-year-old patient with history of recent coronary artery bypass surgery (CABG) was admitted to our hospital with incessant monomorphic ventricular tachycardia (VT) and was treated successfully with radiofrequency catheter ablation (RFA). A new electrophysiological study 3 months post ablation induced no arrhythmia and no implantable cardioverter- defibrillator (ICD) was implanted. Key words: ventricular tachycardia, coronary artery bypass surgery, ablation

Sign in / Sign up

Export Citation Format

Share Document