scholarly journals Autoimmune Hepatitis (AIH) in Acquired Immune Deficiency Syndrome (AIDS): A Case Report and Review of Literature

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Jordan Roussel ◽  
Sudha Pandit ◽  
Paul Jordan ◽  
Moheb Boktor ◽  
Kurt Knowles ◽  
...  

The common causes of abnormal liver chemistries in human immunodeficiency virus (HIV) infected patients are multifactorial. Diagnosis of autoimmune hepatitis (AIH) in HIV infected patients is intriguing but data is scarce. Unmasking of AIH during immune reconstitution in HIV patients after starting antiretroviral therapy is reported but not with advanced acquired immunodeficiency syndrome (AIDS). Here we present a fascinating case of 32-year-old African-American man with advanced AIDS who presented with elevated transaminases. He was diagnosed with AIH before starting antiretroviral therapy and successfully treated with prednisolone and azathioprine with antiretroviral therapy despite very low CD4 count.

2018 ◽  
Author(s):  
Heti Susiyanti Pasaribu

Perilaku seksual beresiko merupakan suatu aktivitas seksual berkaitan dengan hubungan seks yang dilakukan individu dengan pasangan seksnya sehingga rentan tertular penyakit menular seksual seperti HIV/AIDS. Penyakit HIV/AIDS merupakan suatu penyakit yang terus berkembang dan menjadi masalah global yang melanda dunia. Human Immunodeficiency Virus (HIV) yaitu virus yang memperlemah kekebalan tubuh pada manusia. Sedangkan Acquired Immunodeficiency Syndrome atau Acquired Immune Deficiency Syndrome (AIDS) adalah sekumpulan gejala dan infeksi (atau sindrom) yang timbul karena rusaknya sistem kekebalan tubuh manusia akibat infeksi virus HIV, atau infeksi virus-virus lain yang mirip yang menyerang spesies lainnya. Penyakit HIV/AIDS telah menjadi pandemi yang mengkhawatirkan masyarakat dunia karena disamping belum ditemukan obat dan vaksin untuk pencegahan, penyakit ini memiliki window periode dan fase asimtomatik (tanpa gejala) yang relatif panjang dalam perjalanan penyakitnya. Berdasarkan angka kejadian kasus HIV/AIDS terdapat peningkatan diseluruh dunia, termasuk indonesia. Salah satu hal yang dianggap menjadi sumber penyebaran HIV/AIDS adalah perilau seks beresiko. Pemberian penyuluhan sebagai upaya penyebarluasan informasi mengenai HIV/AIDS guna peningkatan pengetahuan masyarakat diharapkan dapat menimbulkan sikap positif masyarakat terhadap HIV. Adapun penyampaian informasi dapat dilakukan dengan berbagai metode misalnya pendidikan kesehatan yang diberikan oleh tenaga kesehatan dapat berupa pamflet atau spanduk di tempat beresiko tinggi.


Sari Pediatri ◽  
2016 ◽  
Vol 9 (2) ◽  
pp. 101
Author(s):  
Ni Ketut Prami Rukmini ◽  
Nia Kurniati ◽  
Dadi Suyoko

Acquired immune deficiency syndrome (AIDS) pertama kali dilaporkan pada awal tahun 1980-an,merupakan infeksi human immunodeficiency virus (HIV). Penyakit ini telah menjadi pandemi yang meluassecara cepat khususnya di Afrika dan Asia. Pada tahun 2005 terdapat 40,3 juta orang di seluruh duniahidup dengan HIV/AIDS, termasuk diantaranya 4,9 juta infeksi baru dan 3,1 juta tercatat meninggaldunia.1-3 Selama tahun 2005, diperkirakan 700.000 anak di seluruh dunia baru terinfeksi HIV. Sekitar90% memperoleh infeksi dari ibunya selama kehamilan, kelahiran atau menyusui.4,5 Di Rumah SakitCipto Mangunkusumo (RSCM) Jakarta, prevalens anak yang terinfeksi HIV 46 anak sepanjang tahun2005. Manifestasi klinis HIV/AIDS ini bermacam-macam sesuai dengan derajat penyakit yang telah terjadi.5Dijumpai beberapa sistem klasifikasi untuk mendiagnosis infeksi HIV pada anak sehingga diharapkandapat menjadi pedoman tata laksana pasien HIV/AIDS.5-9 Tujuan laporan kasus ini untuk mendiskusikantentang anak yang dicurigai terinfeksi HIV, bagaimana menegakkan diagnosis, dan tata laksana AIDSpada anak


Author(s):  
Vincent Ongko Wijaya ◽  
Dony Ardianto ◽  
Gama Sita Setya Pratiwi ◽  
Anton Mahendra ◽  
Glennis Widra Shintyalola ◽  
...  

Tuberkuloma serebral merupakan komplikasi sistem saraf pusat yang jarang dan berbahaya akibat infeksi tuberkulosis (TB). Kondisi imunosupresif pada infeksi human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) merupakan faktor resiko dari perkembangan penyakit. Dilaporkan kasus seorang perempuan berusia 23 tahun dengan riwayat HIV/AIDS dan dalam pengobatan TB aktif dengan keluhan nyeri kepala dan pusing berputar sejak 1 minggu sebelum masuk rumah sakit. Pemeriksaan neurologis dalam batas normal. Pemeriksaan penunjang laboratorium menunjukkan penurunan kadar CD4 absolut dan dilanjutkan CT scan kepala dengan kontras. Pasien mendapat terapi utama deksametason, kotrimoksazol, dan obat anti tuberkulosis. Kata kunci: HIV/AIDS, tuberkuloma, tuberkulosis


2016 ◽  
Vol 3 (3) ◽  
Author(s):  
John M. Humphrey ◽  
Thomas J. Walsh ◽  
Roy M. Gulick

Abstract Invasive Aspergillus (IA) sinusitis is a life-threatening opportunistic infection in immunocompromised individuals, but it is uncommon in human immunodeficiency virus (HIV) infection. To gain a better understanding of the characteristics of IA sinusitis in this population, we present a unique case of chronic IA sinusitis in an HIV-infected patient taking antiretroviral therapy and review the literature summarizing published cases of invasive aspergillosis of the paranasal (n = 41) and mastoid (n = 17) sinuses in HIV-infected individuals. Among these cases, only 4 were reported after 1999, and 98% of patients had acquired immune deficiency syndrome. Orbital invasion occurred in 54% of paranasal sinus cases, whereas intracranial invasion was reported in 53% of mastoid sinus cases. The overall mortality was 79%. We also discuss various clinical and immunologic factors that may play a role in the development of IA and consider the changing epidemiology of aspergillosis in the era of effective antiretroviral therapy.


Author(s):  
Jason J.S. Barton ◽  
Randy H. Kardon ◽  
Daniel Slagel ◽  
H. Stanley Thompson

ABSTRACT:A man with acquired immune deficiency syndrome suddenly developed bilateral complete ptosis and minor vertical gaze limitation. Magnetic resonance imaging revealed a lesion in the midbrain surrounding the sylvian aqueduct in addition to bilateral masses in the caudate nuclei. Pathologic examination showed that the caudate lesions were central nervous system lymphoma of B cell origin, but the midbrain lesion contained only signs of AIDS encephalopathy. The periaqueductal lesion involved the caudal central subnucleus and probably also the subnuclei of the superior and inferior recti of the oculomotor nuclear complex bilaterally.


1996 ◽  
Vol 110 (8) ◽  
pp. 787-788 ◽  
Author(s):  
Adrian Drake-Lee ◽  
Mary Stevenson ◽  
Ivor Donaldson

AbstractWe report a case of previously undiagnosed acquired immunodeficiency syndrome (AIDS) who had a mass in the post-nasal space causing almost complete nasal obstruction. Histology showed both respiratory and squamous epithelium covering an active chronic inflammatory infiltrate. Lymphoma, Kaposi's sarcoma and infiltrative fungal sinusitis were excluded. There was no evidence of the common viruses associated with lesions in AIDS. Unlike adenoid hypertrophy, the lesion was an exuberant growth with an additional chronic inflammatory reaction due to ulceration of the surface epithelium.


2013 ◽  
Vol 17 (3 (67) p.1) ◽  
pp. 51-52
Author(s):  
N. V. Gubin ◽  
N. S. Zavgorodnia

An analysis of the problem of the onset of multiple haemorragіc sarcomatosis has been carried out in case of acquired immune deficiency syndrome at the present stage. A case of the author`s own supervision of Kaposi`s sarcoma from the practice of a forensic medical examination is presented. Spesific characteristics of the medico-legal diagnostics of the presented pathology are determined.


2008 ◽  
Vol 21 (3) ◽  
pp. 277-283 ◽  
Author(s):  
Luísa Helena Maia Leite ◽  
Ana Beatriz de Mattos Marinho Sampaio

OBJECTIVE: To describe the proportion of overweight among patients with human immunodeficiency virus/Acquired Immune Deficiency Syndrome and correlate overweight and highly active antiretroviral therapy with metabolic complications. METHODS: A cross-sectional study was conducted among human immunodeficiency virus/Acquired Immune Deficiency Syndrome outpatients undergoing nutritional therapy from 2000 to 2006 in a University Health Center. The sample consisted of 393 human immunodeficiency virus/Acquired Immune Deficiency Syndrome patients. Nutritional and medical records were used as a source of data on personal, clinical and biochemical information. Data analysis included descriptive statistics and the Chi-square test. RESULTS: Sixty-nine percent of the patients were males aging from 26 to 49 years. Overweight and obesity were identified in 49% of this population. The most important metabolic complications were low levels of high-density lipoprotein (70%) and high levels of triglycerides (48%) and cholesterol (40%). Higher body mass index was associated with higher lipid levels and more evidence of insulin resistance. CONCLUSION: This study demonstrated an important proportion of overweight and obesity among human immunodeficiency virus/Acquired Immune Deficiency Syndrome patients. These results suggest that nutritional interventions and lifestyle modifications may be useful strategies to decrease the cardiovascular risk in this population.


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