scholarly journals Adherence to Antiplatelet Therapy after Coronary Intervention among Patients with Myocardial Infarction Attending Vietnam National Heart Institute

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Ngoc Minh Luu ◽  
Anh Tuan Dinh ◽  
Thi Thu Ha Nguyen ◽  
Van Huy Nguyen

Adherence to antiplatelet therapy is critical to successful treatment of cardiovascular conditions. However, little has been known about this issue in the context of constrained resources such as in Vietnam. The objective of this study was to examine the adherence to antiplatelet therapy among patients receiving acute myocardial infarction interventions and its associated factors. In a cross-sectional survey design, 175 adult patients revisiting Vietnam National Heart Institute diagnosed with acute myocardial infarction were approached for data collection from October 2014 to June 2015. Adherence to antiplatelet therapy was assessed by asking patients whether they took taking antiplatelet regularly as per medication (do not miss any dose at the specified time) for any type of antiplatelet (aspirin, clopidogrel, ticlopidine...) during the last month before the participants came back to take re-examinations. The results indicated that the adherence to antiplatelet therapy among patients was quite high at 1 month; it begins to decline by 6 months, 12 months, and more than 12 months (less than 1 month was 90.29%; from 1 to 6 months 88.0%, from 6 to 12 months 75.43%, and after 12 months only 46.29% of patients). Multivariable logistic regression was utilized to detect factors associated with the adherence to antiplatelet therapy. It showed that patients with average income per month of $300 or more (OR=2.92, 95% CI=1.24-6.89), distance to the hospital of less than 50km (OR=2.48, 95% CI: 1.12-5.52), taking medicine under doctor’s instructions (OR=3.65; 95% CI=1.13-11.70), and timely re-examination (OR=3.99, 95% CI=1.08-14.73) were more likely to follow the therapy. In general, the study suggested that to increase the likelihood of adherence to antiplatelet therapy it is important to establish a continuous care system after discharging from hospital.

2019 ◽  
Author(s):  
Nourah Al-Orainan ◽  
Adel Mohamed EL-Shabasy ◽  
Khawlah Alamin Al-Shanqiti ◽  
Rawan Awad Al-Harbi ◽  
Hadeel Rajeh Alnashri ◽  
...  

BACKGROUND Sepsis is a state of organ dysfunction caused by an impaired host response to infection. It is one of the leading causes of death globally. Sepsis, acute myocardial infarction (AMI), and stroke share the primary management requirement of rapid intervention. This could be achieved through early presentation to the hospital, which demands previous knowledge of the disease to ensure better outcomes. OBJECTIVE Our study aimed to assess the level of public awareness of sepsis compared with AMI and stroke. METHODS This was a cross-sectional survey study performed in June and July 2018, with 1354 participants from Jeddah, Saudi Arabia, aged ≥18 years. Data entry was performed using Microsoft Excel and statistical analysis including chi-square tests and multilogistic regression was performed using SPSS software. RESULTS A total of 1354 participants were included. Only 56.72% (768/1354) had heard of the term “sepsis” and 48.44% (372/768) of these participants were able to correctly identify it. In addition, 88.33% (1196/1354) had heard the term “myocardial infarction” and 64.63% (773/1196) knew the correct definition of that condition. Stroke was recognized by 81.46% (1103/1354) of participants and 59.20% (653/1103) of these participants correctly identified the condition. The difference between those who had heard of these diseases and those who knew the correct definition significantly differed from the values for awareness of sepsis and its definition. CONCLUSIONS We found that public awareness and knowledge of sepsis are poor amongst the population of Jeddah compared with the awareness and knowledge of AMI and stroke. This lack of knowledge may pose a serious obstruction to the prompt management needed to limit fatal outcomes.


2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
C.-Y Hsu ◽  
J.-S Yeh ◽  
C.-Y Huang

Abstract Background Recently, both unguided (platelet function testing independent) and guided (platelet function testing dependent) DAPT de-escalation strategies have been investigated in different clinical studies but the data is still limited and conflicting. The aim of this study was to examine the effect of switching dual antiplatelet therapy (DAPT) on the major vascular risk after acute myocardial infarction (AMI) in patients undergoing percutaneous coronary intervention (PCI) by using Taiwan National Health Insurance Research Database. Methods In total, 1,903 and 4,059 patients defined as switched to aspirin and clopidogrel (switched DAPT) and continuation of aspirin and ticagrelor (unswitched DAPT) cohort, respectively who had received PCI during AMI hospitalization, on aspirin and ticagrelor initially and without occurring adverse events at 3 months were evaluated between 2013 and 2015. An inverse probability treatment of weighted approach was adopted to balance the baseline differences between two groups and Cox proportional hazard regression and competing risk regression were used to evaluated the effect of switching DAPT on death, AMI readmission, major bleeding and non-major clinically relevant bleeding. Results The incidence rates (per 100 person-year) of death and AMI readmission were 3.97 (95% confidence interval [CI] = 3.19–4.84) and 3.84 (95% CI = 3.09–4.73) in switched cohort and 1.83 (95% CI = 1.47–2.24) and 2.23 (95% CI = 1.82–2.68) in unswitched cohort, respectively. After adjustment for patients' clinical variables, switched cohort had higher risk of death (adjusted hazard ratio = 2.18, 95% CI = 1.62–2.93, P<0.001), and AMI readmission (adjusted sub-distribution ratio = 1.72, 95% CI = 1.27–2.34, P<0.001) compared to these in unswitched cohort; however, there was no difference in the risk of bleeding. Subgroup analysis showed a similar findings in many specific groups, except the patients who were younger age and had lower comorbidity score. Conclusion Switching DAPT might increase the risk of death and AMI readmission among patients with AMI undergoing PCI.


2017 ◽  
Vol 1 (2) ◽  
pp. 33-50
Author(s):  
Zarnab Tariq ◽  
Majid Kaleem

AbstractBackground: To compare between the outcomes of streptokinase and primary PCI in acute myocardial infarction. The inappropriate treatment, misdiagnosis, contraindications of procedures can result in complications of procedures and increased mortality of patients. The present study aimed to compare between the outcomes of streptokinase and primary percutaneous coronary intervention in acute myocardial infarction patients to minimize the death rates in MI patients.Methodology: The descriptive study was conducted at Gulab Devi Chest Hospital. All the samples were collected from cardiac department. A Performa was designed for recording the risk factors, ST elevation, clinical findings and lab results of the patients.Results: In this cross-sectional study of 100 patients, the mean age was 51.02+ 10.956. Male gender was predominant. There were more chances (67.00%) of acute LVF in streptokinase and less chances (21.00%) in primary PCI. According to this study, there was more chances (67.00%) of cardiogenic shock in streptokinase and less chances (21.00%) in primary PCI. In this study, there were equal chances of stroke in streptokinase and primary PCI. In this study there were more chances (28.00%) of bleeding from any site in streptokinase and less chances (0%) in primary PCI. According to results there were chances (24.00%) of renal failure in streptokinase and less chances (0%) in primary PCI. There were more chances (9.43%) of rescue PCI in streptokinase and less chances in primary PCI. In this study, there were more chances of arrhythmias (26.41%) in streptokinase patients and less chances in primary PCI. In this study, there were also more chances of death (1.92%) in streptokinase and less chance in primary PCI. So according to my study primary PCI was better than streptokinase with less complications.Conclusion: Primary PCI was better than streptokinase to cure the myocardial infarction and better to minimize the complications after procedure.


10.2196/16195 ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. e16195
Author(s):  
Nourah Al-Orainan ◽  
Adel Mohamed EL-Shabasy ◽  
Khawlah Alamin Al-Shanqiti ◽  
Rawan Awad Al-Harbi ◽  
Hadeel Rajeh Alnashri ◽  
...  

Background Sepsis is a state of organ dysfunction caused by an impaired host response to infection. It is one of the leading causes of death globally. Sepsis, acute myocardial infarction (AMI), and stroke share the primary management requirement of rapid intervention. This could be achieved through early presentation to the hospital, which demands previous knowledge of the disease to ensure better outcomes. Objective Our study aimed to assess the level of public awareness of sepsis compared with AMI and stroke. Methods This was a cross-sectional survey study performed in June and July 2018, with 1354 participants from Jeddah, Saudi Arabia, aged ≥18 years. Data entry was performed using Microsoft Excel and statistical analysis including chi-square tests and multilogistic regression was performed using SPSS software. Results A total of 1354 participants were included. Only 56.72% (768/1354) had heard of the term “sepsis” and 48.44% (372/768) of these participants were able to correctly identify it. In addition, 88.33% (1196/1354) had heard the term “myocardial infarction” and 64.63% (773/1196) knew the correct definition of that condition. Stroke was recognized by 81.46% (1103/1354) of participants and 59.20% (653/1103) of these participants correctly identified the condition. The difference between those who had heard of these diseases and those who knew the correct definition significantly differed from the values for awareness of sepsis and its definition. Conclusions We found that public awareness and knowledge of sepsis are poor amongst the population of Jeddah compared with the awareness and knowledge of AMI and stroke. This lack of knowledge may pose a serious obstruction to the prompt management needed to limit fatal outcomes.


Author(s):  
Parag Rishipathak ◽  
Shrimathy Vijayraghavan ◽  
Anand Hinduja

Aim: Acute Myocardial Infarction is one of the commonest medical emergencies encountered by Emergency Medical Professionals. The EMS professional is the first responder in the hospital emergency room. Primary percutaneous coronary intervention (PCI) performed in a timely manner is the preferred method of treatment for ST-elevation myocardial infarction (STEMI). This study aims to assess perception regarding factors causing delay of Door to Balloon Time (DTBT) in Acute Myocardial Infarction management amongst Emergency Medical Professionals. Study Design: Cross Sectional Descriptive Study. Place and Duration of Study: Symbiosis Centre for Health Skills, Pune in May 2021. Materials and Methods: The study was conducted amongst 120 Emergency Medical Professionals in Pune, India. The data was collected during the month of May 2021. Professionals who have completed Post Graduate Diploma in Emergency Medical Services were included in the study. A pre tested and validated questionnaire developed by Jafery et al was utilized to assess the knowledge and perception level among Emergency Medical Professionals. Results and Discussion: The study provided insight into the factors causing delay in DTBT. An overwhelming majority of respondents blamed the shortage of general and specialist staff for the delay in DTBT. Shortage of CCU beds was also reported as the key factor in the hold up by as many as 71% of the respondents. Cardiac Cath lab availability and ECG equipment shortage were considered to be hindrances by nearly half the respondents. Lack of structured protocol and poor information communication was also hampering the achievement of ideal DTBT. Conclusion: Emergency Medical Professionals have adequate knowledge of their role and the barriers that prevent timely clinical care. The study offers avenues for improvement in various clinical and non-clinical areas so as to achieve the desired clinical goals.


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