The Prevalence of Restless Legs Syndrome in Patients with Migraine: A Systematic Review and Meta-Analysis

Background. Migraine is a severe and debilitating neurologic disorder and is claimed to be the sixth disabling illness in the world. This study aimed to determine the overall prevalence of restless legs syndrome (RLS) in patients with migraine through a systematic review and meta-analysis. Methods. To identify and select related studies, the Scopus, ScienceDirect, Embase, SID, IranDoc, Web of Science, Knowledge Network System Medline (PubMed), and Google Scholar databases were searched. All related cross-sectional studies, published in English or Persian language between January 2000 and December 2019 and using the keywords such as migraine, restless leg syndrome, sleep disorder, RLS, and migraine disorder, were collected. The heterogeneity of the studies was assessed using the I2 index, and the data analysis was performed using the Comprehensive Meta-Analysis software. Results. Analysis was conducted on the reported results of the final 12 articles with the total sample size of 15196. The overall prevalence of RLS in patients with migraine was 16.3% (95% CI: 12.6–20.8%). The prevalence of RLS migraine patients decreased with increasing the sample size, and the prevalence of RLS migraine patients increased with increasing the research year, which was statistically significant (P<0.05). Conclusion. This study highlights that RLS is high in patients with migraine, and therefore, the clinicians should be aware of its incidence and take preventive measures.

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Association between restless legs syndrome and peripheral neuropathy: A systematic review and meta‐analysis

European Journal of Neurology ◽

10.1111/ene.14840 ◽

2021 ◽

Author(s):

Félix Javier Jiménez‐Jiménez ◽

Hortensia Alonso‐Navarro ◽

Elena García‐Martín ◽

José A.G. Agúndez

Keyword(s):

Systematic Review ◽

Peripheral Neuropathy ◽

Restless Legs Syndrome ◽

Meta Analysis ◽

Restless Legs

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We need to do better: A systematic review and meta-analysis of diagnostic test accuracy of restless legs syndrome screening instruments

Sleep Medicine Reviews ◽

10.1016/j.smrv.2021.101461 ◽

2021 ◽

Vol 58 ◽

pp. 101461

Author(s):

Stephany Fulda ◽

Richard P. Allen ◽

Christopher J. Earley ◽

Birgit Högl ◽

Diego Garcia-Borreguero ◽

...

Keyword(s):

Systematic Review ◽

Diagnostic Test ◽

Restless Legs Syndrome ◽

Meta Analysis ◽

Diagnostic Test Accuracy ◽

Test Accuracy ◽

Screening Instruments ◽

Restless Legs

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The prevalence of sleep disturbances among physicians and nurses facing the COVID-19 patients: a systematic review and meta-analysis

Globalization and Health ◽

10.1186/s12992-020-00620-0 ◽

2020 ◽

Vol 16 (1) ◽

Author(s):

Nader Salari ◽

Habibolah Khazaie ◽

Amin Hosseinian-Far ◽

Hooman Ghasemi ◽

Masoud Mohammadi ◽

...

Keyword(s):

Systematic Review ◽

Sample Size ◽

Medical Staff ◽

Sleep Disturbances ◽

Meta Analysis ◽

Workplace Stress ◽

Cross Sectional ◽

Significance Level ◽

Nurses And Physicians ◽

As Stress

Abstract Background In all epidemics, healthcare staff are at the centre of risks and damages caused by pathogens. Today, nurses and physicians are faced with unprecedented work pressures in the face of the COVID-19 pandemic, resulting in several psychological disorders such as stress, anxiety and sleep disturbances. The aim of this study is to investigate the prevalence of sleep disturbances in hospital nurses and physicians facing the COVID-19 patients. Method A systematic review and metanalysis was conducted in accordance with the PRISMA criteria. The PubMed, Scopus, Science direct, Web of science, CINHAL, Medline, and Google Scholar databases were searched with no lower time-limt and until 24 June 2020. The heterogeneity of the studies was measured using I2 test and the publication bias was assessed by the Egger’s test at the significance level of 0.05. Results The I2 test was used to evaluate the heterogeneity of the selected studies, based on the results of I2 test, the prevalence of sleep disturbances in nurses and physicians is I2: 97.4% and I2: 97.3% respectively. After following the systematic review processes, 7 cross-sectional studies were selected for meta-analysis. Six studies with the sample size of 3745 nurses were examined in and the prevalence of sleep disturbances was approximated to be 34.8% (95% CI: 24.8-46.4%). The prevalence of sleep disturbances in physicians was also measured in 5 studies with the sample size of 2123 physicians. According to the results, the prevalence of sleep disturbances in physicians caring for the COVID-19 patients was reported to be 41.6% (95% CI: 27.7-57%). Conclusion Healthcare workers, as the front line of the fight against COVID-19, are more vulnerable to the harmful effects of this disease than other groups in society. Increasing workplace stress increases sleep disturbances in the medical staff, especially nurses and physicians. In other words, increased stress due to the exposure to COVID-19 increases the prevalence of sleep disturbances in nurses and physicians. Therefore, it is important for health policymakers to provide solutions and interventions to reduce the workplace stress and pressures on medical staff.

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Bidirectional association between irritable bowel syndrome and restless legs syndrome: a systematic review and meta-analysis

Sleep Medicine ◽

10.1016/j.sleep.2020.12.002 ◽

2021 ◽

Vol 77 ◽

pp. 104-111

Author(s):

Jing Guo ◽

Lixia Pei ◽

Lu Chen ◽

Hao Chen ◽

Dongmei Gu ◽

...

Keyword(s):

Systematic Review ◽

Irritable Bowel Syndrome ◽

Restless Legs Syndrome ◽

Meta Analysis ◽

Restless Legs ◽

Bidirectional Association ◽

Irritable Bowel

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The worldwide prevalence of the Dupuytren disease: a comprehensive systematic review and meta-analysis

Journal of Orthopaedic Surgery and Research ◽

10.1186/s13018-020-01999-7 ◽

2020 ◽

Vol 15 (1) ◽

Author(s):

Nader Salari ◽

Mohammadbagher Heydari ◽

Masoud Hassanabadi ◽

Mohsen Kazeminia ◽

Nikzad Farshchian ◽

...

Keyword(s):

Systematic Review ◽

Sample Size ◽

Meta Analysis ◽

Total Sample ◽

World Health ◽

Palmar Fascia ◽

The World ◽

Patients With Diabetes ◽

Health Organization ◽

Dupuytren Disease

Abstract Background The Dupuytren disease is a benign fibroproliferative disorder that leads to the formation of the collagen knots and fibres in the palmar fascia. The previous studies reveal different levels of Dupuytren’s prevalence worldwide; hence, this study uses meta-analysis to approximate the prevalence of Dupuytren globally. Methods In this study, systematic review and meta-analysis have been conducted on the previous studies focused on the prevalence of the Dupuytren disease. The search keywords were Prevalence, Prevalent, Epidemiology, Dupuytren Contracture, Dupuytren and Incidence. Subsequently, SID, MagIran, ScienceDirect, Embase, Scopus, PubMed and Web of Science databases and Google Scholar search engine were searched without a lower time limit and until June 2020. In order to analyse reliable studies, the stochastic effects model was used and the I2 index was applied to test the heterogeneity of the selected studies. Data analysis was performed within the Comprehensive Meta-Analysis Software version 2.0. Results By evaluating 85 studies (10 in Asia, 56 in Europe, 2 in Africa and 17 studies in America) with a total sample size of 6628506 individuals, the prevalence of Dupuytren disease in the world is found as 8.2% (95% CI 5.7–11.7%). The highest prevalence rate is reported in Africa with 17.2% (95% CI 13–22.3%). According to the subgroup analysis, in terms of underlying diseases, the highest prevalence was obtained in patients with type 1 diabetes with 34.1% (95% CI 25–44.6%). The results of meta-regression revealed a decreasing trend in the prevalence of Dupuytren disease by increasing the sample size and the research year (P < 0.05). Conclusion The results of this study show that the prevalence of Dupuytren disease is particularly higher in alcoholic patients with diabetes. Therefore, the officials of the World Health Organization should design measures for the prevention and treatment of this disease.

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Prevalence of Anxiety in Medical Students during the COVID-19 Pandemic: A Rapid Systematic Review with Meta-Analysis

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17186603 ◽

2020 ◽

Vol 17 (18) ◽

pp. 6603 ◽

Cited By ~ 1

Author(s):

Isabel Lasheras ◽

Patricia Gracia-García ◽

Darren Lipnicki ◽

Juan Bueno-Notivol ◽

Raúl López-Antón ◽

...

Keyword(s):

Systematic Review ◽

Medical Students ◽

Meta Analysis ◽

Total Sample ◽

Significant Heterogeneity ◽

The Novel ◽

Cross Sectional ◽

Manual Search ◽

Novel Coronavirus ◽

Treatment Prognosis

The novel coronavirus disease (COVID-19) pandemic has brought a great deal of pressure for medical students, who typically show elevated anxiety rates. Our aim is to investigate the prevalence of anxiety in medical students during this pandemic. This systematic review and mini meta-analysis has been conducted following the PRISMA guidelines. Two researchers independently searched PubMed on 26 August 2020 for cross-sectional studies on medical students during the COVID-19 outbreak, with no language restrictions applied. We then performed a manual search to detect other potentially eligible investigations. To the 1361 records retrieved in the initial search, 4 more were added by manual search on medRxiv. Finally, eight studies were finally included for qualitative and quantitative analysis, which yielded an estimated prevalence of anxiety of 28% (95% CI: 22–34%), with significant heterogeneity between studies. The prevalence of anxiety in medical students is similar to that prior to the pandemic but correlates with several specific COVID-related stressors. While some preventive and risk factors have been previously identified in a non-pandemic context, knowledge and cognitions on COVID-19 transmission, treatment, prognosis and prevention negatively correlate with anxiety, emerging as a key preventive factor that may provide a rationale for why the levels of anxiety have remained stable in medical students during the pandemic while increasing in their non-medical peers and the general population. Other reasons for the invariability of anxiety rates in this population are discussed. A major limitation of our review is that Chinese students comprised 89% the total sample, which could compromise the external validity of our work

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