scholarly journals The Expressions and Mechanisms of Sarcomeric Proteins in Cancers

2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Xiaojing Yang ◽  
Hanru Ren ◽  
Xiaomao Guo ◽  
Chaosu Hu ◽  
Jie Fu
Keyword(s):  
Tumor Cell ◽  
Model Organisms ◽  
Cancer Genes ◽  
Biological Functions ◽  
Sarcomeric Proteins ◽  
Diverse Species ◽  
Cell Metastasis ◽  
Tumor Cell Metastasis ◽  
Human Carcinomas

The sarcomeric proteins control the movement of cells in diverse species, whereas the deregulation can induce tumours in model organisms and occurs in human carcinomas. Sarcomeric proteins are recognized as oncogene and related to tumor cell metastasis. Recent insights into their expressions and functions have led to new cancer therapeutic opportunities. In this review, we appraise the evidence for the sarcomeric proteins as cancer genes and discuss cancer-relevant biological functions, potential mechanisms by which sarcomeric proteins activity is altered in cancer.

scholarly journals 1-Deoxynojirimycin: Sources, Extraction, Analysis and Biological Functions

2017 ◽  
Vol 12 (9) ◽  
pp. 1934578X1701200 ◽  
Author(s):  
Niannian Wang ◽  
Feifei Zhu ◽  
Keping Chen
Keyword(s):  
Tumor Cell ◽  
Biological Activities ◽  
Biological Functions ◽  
Physiological Functions ◽  
Fat Accumulation ◽  
Cell Metastasis ◽  
Tumor Cell Metastasis ◽  
Treatment Of Diabetes ◽  
Technical Advice

1-Deoxynojirimycin (DNJ), a natural polyhydroxylated piperidine alkaloid, is attracting growing attention due to its important biological functions. This paper introduces the discovery and origins of DNJ, its extraction, purification, and physiological functions in the treatment of diabetes. The mechanisms of DNJ in the inhibition of fat accumulation and tumor cell metastasis are also discussed. In addition, the prospects and challenges of DNJ for practical production are proposed. This work aims to provide technical advice on obtaining DNJ and a fuller understanding of its biological activities.

Enhanced Endothelial Cell Retraction Mediated by 12(S)-HETE: A Proposed Mechanism for the Role of Platelets in Tumor Cell Metastasis

1994 ◽  
Vol 210 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Kenneth V. Honn ◽  
Dean G. Tang ◽  
Irma M. Grossi ◽  
Colette Renaud ◽  
Zofia M. Duniec ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Tumor Cell ◽  
Cell Metastasis ◽  
Tumor Cell Metastasis ◽  
Endothelial Cell Retraction ◽  
Cell Retraction

Diets Rich in Fish Oil Cannot Control Tumor Cell Metastasis

1987 ◽  
Vol 31 (6) ◽  
pp. 342-348 ◽  
Author(s):  
Will J. Kort ◽  
Ineke M. Weijma ◽  
Toos E.M. Stehmann ◽  
Antoine J. Vergroesen ◽  
Dick L. Westbroek
Keyword(s):  
Tumor Cell ◽  
Fish Oil ◽  
Cell Metastasis ◽  
Tumor Cell Metastasis ◽  
Control Tumor
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