scholarly journals Influencing Factors of Gastrointestinal Function Recovery after Gastrointestinal Malignant Tumor

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Liang Wang ◽  
Xiaofeng Zhang ◽  
Huaping Xu ◽  
Yisheng Zhang ◽  
Lianghui Shi
Keyword(s):  
Malignant Tumor ◽  
Recovery Time ◽  
Postoperative Recovery ◽  
Difficult Problem ◽  
Bowel Sound ◽  
Gastrointestinal Function ◽  
Gastrointestinal Malignancies ◽  
Factors Affecting ◽  
Bowel Sounds ◽  
Fasting Time

Gastric cancer is a malignant tumor with a high incidence in the world, and the incidence rate only increases every year. Because of the loss of mental property caused by surgery and postoperative recovery treatment, it has become a difficult problem for many families to solve. Exploring the factors affecting the recovery of gastrointestinal function after surgery to accelerate the recovery has become one of the important research topics of current medical experts and scholars. The purpose of this article is to explore the factors affecting the recovery of gastrointestinal function after gastrointestinal malignancies. In this paper, firstly through experimental investigation, the fasting time and operation method of patients undergoing gastrointestinal malignant tumor surgery are used as variables to conduct a controlled experiment, and the first defecation time, exhaust time, and bowel sound recovery of the experimental subjects after surgery are recorded. Changes in time and other indicators are compared to verify whether they affect the recovery of gastrointestinal function. Experimental data showed that the recovery time of bowel sounds was 29.10 ± 11.09 h in patients with fasting time less than or equal to 2 days after operation, the time of first exhaustion was 28.75 ± 27.80 h, and the time of first defecation was 54.70 ± 39.40 h. The recovery time of bowel sounds in patients with fasting time longer than 2 days was 40.47 ± 9.40 h, the first exhaust time was 71.40 ± 17.54 h, and the first defecation time was 98.30 ± 28.16 h. Therefore, resuming diet as soon as possible after operation is beneficial to the recovery of gastrointestinal function in patients with gastrointestinal malignancies.

COMPLEX PROSTHETIC REHABILITATION OF THE PATIENT WITH MALIGNANT TUMOR OF OROPHARYNGEAL REGION DURING ANTITUMOR TREATMENT: CASE REPORT

2019 ◽  
Vol 65 (2) ◽  
pp. 287-293
Author(s):  
Yekaterina Izhnina ◽  
Yekaterina Kochurova ◽  
Natalya Lapina ◽  
Karina Seferyan
Keyword(s):  
Case Report ◽  
Malignant Tumor ◽  
Methodological Approach ◽  
Difficult Problem ◽  
Prosthetic Rehabilitation ◽  
Anatomic Structure

Treatment of patients with malignant tumor of oropharyngeal region is a difficult problem due to the last detection of diseases and complex anatomic structure, despite the emergence new and improvement methods of the treatment of cancer of oropharyngeal region. Complex rehabilitation of this patients presents great difficulties due to the disturbance of breath, swallowing, speech, and the lack of a single methodological approach to treatment. It is needs to improve the effectiveness of prosthetic care for patients with malignant tumor of oropharyngeal region.

scholarly journals Independent Factors Affecting Recovery Time After Sedation in Patients with Intellectual Disabilities

2015 ◽  
Vol 9 (1) ◽  
pp. 146-149 ◽  
Author(s):  
Shigeru Maeda ◽  
Yumiko Tomayasu ◽  
Hitoshi Higuchi ◽  
Minako Ishii-Maruhama ◽  
Ayaka Yamane ◽  
...  
Keyword(s):  
Intellectual Disabilities ◽  
Psychotropic Drugs ◽  
Recovery Time ◽  
Dental Treatment ◽  
Outcome Variable ◽  
Intravenous Sedation ◽  
Factors Affecting ◽  
Oral Midazolam ◽  
Prolonged Recovery ◽  
Independent Determinant

Purpose:The purpose of this study was to identify independent factors associated with prolonged recovery time after intravenous sedation for dental treatment in patients with intellectual disabilities.Methods:This study was designed as a prospective cohort study. Participants were patients with intellectual disabilities, for whom sedation for dental treatment was planned in Okayama University Hospital. The outcome variable was recovery time. The predictor variables were patient background, antiepileptic and psychotropic drugs, and anesthesia-related variables. Factors affecting the outcome were examined with multiple regression analysis.Results:We enrolled 260 cases in this study. Oral midazolam was a strong independent determinant in prolonged recovery time. Teeth extraction, short treatment time and lower body mass index were significant independent predictors of prolonged recovery time.Conclusion:Oral midazolam is a clear independent determinant of prolonged recovery time after sedation, while psychotropic drugs and antiepileptic drugs were not independent determinants in this study.

scholarly journals Effect of stellate ganglion block on postoperative recovery of gastrointestinal function in patients undergoing surgery with general anaesthesia: a meta-analysis

BMC Surgery ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Bei Wen ◽  
Yajie Wang ◽  
Cong Zhang ◽  
Zhijian Fu
Keyword(s):  
General Anaesthesia ◽  
Meta Analysis ◽  
Stellate Ganglion ◽  
Gastrointestinal Surgery ◽  
Stellate Ganglion Block ◽  
Postoperative Recovery ◽  
Cochrane Library ◽  
Gastrointestinal Function ◽  
Ganglion Block ◽  
Abdominal Bloating

Abstract Background The return of gastrointestinal function is an important sign of postoperative recovery in patients undergoing surgery with general anaesthesia. We aimed to summarize the effects of stellate ganglion block on the recovery of gastrointestinal function as a means of exploring methods through which anaesthesiologists can contribute to postoperative patient recovery. Methods We performed a quantitative systematic review of randomized controlled trials published between January 1, 1988, and November 11, 2019, in PubMed, the Cochrane Library, China National Knowledge Infrastructure, Chinese VIP Information, and the Wanfang and SinoMed databases. Study quality was assessed by using the GRADE criteria and bias of included studies were assessed using the revised Cochrane risk-of-bias tool for randomized trials. The time to peristaltic sound resumption, flatus, postoperative eating and the incidence of abdominal bloating in the stellate ganglion block and control groups were compared. The control group consisted of either a stellate ganglion block with normal saline or no treatment. Meta-analysis was performed using Review Manager software. Results After searching for relevant articles, 281 studies were identified, and five articles with data on 274 patients were eligible. Regarding postoperative flatus time, stellate ganglion block resulted in a mean reduction of 15 h (P = 0.02); then a sensitivity analysis was performed, and the standard mean difference decreased to 6 h (P = 0.007). For gastrointestinal surgery, the mean reduction was 23.92 h (P = 0.0002). As for the evaluation of the recovery of peristaltic sounds, stellate ganglion block promoted the recovery of regular peristaltic bowel sounds an average of 14.67 h earlier than in the control (P = 0.0008). When it comes to nutrients, stellate ganglion block shortened the total parenteral nutrition time by more than 50 h in patients who had undergone gastrointestinal surgery (P<0.00001). Finally, stellate ganglion block prevented the occurrence of postoperative abdominal bloating (P = 0.001).) No complications related to stellate ganglion block were reported. Conclusion Stellate ganglion block may promote postoperative gastrointestinal recovery in patients undergoing various surgeries under general anaesthesia. However, additional trials investigating the use of stellate ganglion block are necessary to confirm our finding. Trial registration This meta-analysis has been registered at the International Prospective Register of Systematic Reviews (registration number CRD42020157602).

scholarly journals Enhanced Recovery after Surgery Protocol Accelerates Recovery of Lumbar Disc Herniation among Elderly Patients Undergoing Discectomy via Promoting Gastrointestinal Function

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Xiaohai Zuo ◽  
Linbang Wang ◽  
Longzhu He ◽  
Pei Li ◽  
Dandan Zhou ◽  
...  
Keyword(s):  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Recovery Time ◽  
Enhanced Recovery ◽  
Enhanced Recovery After Surgery ◽  
Lumbar Disc ◽  
Length Of Hospital Stay ◽  
Feeding Time ◽  
Gastrointestinal Function ◽  
The Difference

This study aimed to analyze the effect of the enhanced recovery after surgery (ERAS) protocol on the recovery of gastrointestinal function in patients with lumbar disc herniation after discectomy. A total of 179 patients with lumbar disc herniation were randomly divided into the ERAS and non-ERAS groups. The non-ERAS group received routine nursing, and the ERAS group received ERAS strategy. The two groups were compared for general recovery indicators such as postoperative hemoglobin and prealbumin, satisfaction, and length of hospital stay. Gastrointestinal function was also evaluated, such as postoperative feeding time, intestinal chirping recovery time, intestinal exhaust gas recovery time, and complications such as ileus, nausea, and vomiting. The satisfaction of patients in the ERAS group (86.15 ± 2.43) was significantly higher than that in the non-ERAS group (77.19 ± 3.32), and the difference was statistically significant ( P < 0.05 ). The average time of eating in the ERAS group was 2.27 h after surgery. In addition, the amount of eating in the ERAS group was significantly better than that in the non-ERAS group, and the difference was statistically significant. In the ERAS group, intestinal chirping recovery time recovered to normal time, and exhaust recovery time and average defecation time were significantly shorter than those in the non-ERAS group. In the ERAS group, the average amount of hemoglobin and prealbumin decreased 3 days after operation, which was significantly lower than that in the non-ERAS group. To sum up, ERAS has an evident effect on the recovery of gastrointestinal function after discectomy of disc herniation, which can promote the recovery of patients.

scholarly journals The Effect and Nursing of Indwelling Nasal Jejunal Feeding Tube for Enteral Nutrition in Acute Severe Pancreatitis

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Xiaoqin Zhu ◽  
Zhaolin Chen
Keyword(s):  
Enteral Nutrition ◽  
Recovery Time ◽  
Length Of Hospital Stay ◽  
Nursing Intervention ◽  
Gastrointestinal Function ◽  
Observation Group ◽  
Research Subjects ◽  
Acute Severe Pancreatitis ◽  
Severe Pancreatitis ◽  
Nasojejunal Tube

Objective: To analyze the effect of enteral nutrition and nursing intervention in patients with indwelling nasojejunal tube in acute severe pancreatitis. Methods: Sixty cases of patients with indwelt nasojejunal tubes treated in our hospital from August 2019 to August 2020 were divided into routine group and observation group as research subjects. Patients in both groups received enteral nutrition, patients in the routine group received routine care, and patients in the observation group received quality care. The recovery time of gastrointestinal function, length of hospital stay, hospitalization cost, nutritional indicators and incidence of complications in the two groups were compared. Results: The recovery time of gastrointestinal function in observation group was lower than that in routine group, P<0.05; The length and cost of hospitalization in observation group were lower than those in routine group, P<0.05; The nutritional indexes in observation group were higher than those in routine group, P<0.05; The incidence of complications in observation group was lower than that in routine group, P<0.05. Conclusion: Quality nursing service improve the effect of enteral nutrition, so as to ensure that patients get sufficient nutritional support. Its effect is remarkable and it is worthy of widespread clinical application.

The factors affecting objective response in patients with advanced malignant tumor treated with H101, an E1B-55kD deleted oncolytic adenovirus

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 13166-13166
Author(s):  
H. Xia ◽  
R. Zhao ◽  
W. Hu ◽  
Z. Li ◽  
G. Hu ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Phase Ii ◽  
Malignant Tumor ◽  
Tumor Response ◽  
Objective Response ◽  
Intratumoral Injection ◽  
Factors Affecting ◽  
Group A ◽  
Multivariable Regression ◽  
Group B

13166 Background: H101 is E1B-55kD deleted oncolytic adenovirus which can selectively replicate in tumor cells. Previous phase I/II clinical trials have shown that H101 has certain anti-tumor effects and is safe when applied to patients by intratumoral injection. The aim of this study is to identify the factors affecting tumor response in patients with advanced malignant tumor treated with H101. Methods: All patients in H101 phase II clinical trial were retrospectively reviewed. They were treated with either H101 alone (group A) or H101 combined with conventional chemotherapy (group B). H101 was administrated by intratumoral injection at the dosage of 5×1011 viral particles, once a day for 5 consecutive days. The objective response was evaluated according to WHO criteria and the adverse events were recorded. All information required for this study was retrieved from the database of H101 phase II clinical trial. Chi square test and stepwise multivariable regression were used for statistic analysis with a significant level of p<0.05. Results: There were 106 evaluable patients in this study, 54 in group A (36 males and 18 females, age: 36–78 years), 52 in group B (35 males and 17 females, age: 18–76 years). The diagnoses of these patients include head & neck cancer (54), breast cancer (13) and others (39). All were in the advanced stage of the disease, and refractory or resistant to chemo and radio therapy. The objective response rate was higher in group B (23.1%) as compared to group A (16.7%). In patients with response (CR or PR), 62.5% of them experienced fever after the injection of H101, in contrast, only 18.9% of the patients without response did so. The difference was statistically significant (p<0.01). In the stepwise multivariable regression analysis, tumor response was used as dependent variable, and the independent variables included demographic data, clinical and pathologic type of the tumor, and treatment regimen. The result revealed that tumor response was positively correlated with the fever after H101 injection (p<0.01). Conclusions: H101 has certain anti-tumor efficacy in patients with advanced malignancies, which might be enhanced by the fever after H101 injection and/or combining with chemotherapy. [Table: see text]

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