scholarly journals Care of Maintenance Hemodialysis Patients through Intelligent Algorithm-Based Low-Dose Digital Subtraction Angiography

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Jianhua Hong

Objective. The study aimed to explore the application value of artificial intelligence (AI)-based low-dose digital subtraction angiography (DSA) in the care of maintenance hemodialysis (MHD) patients. Methods. The characteristics of DSA imaging were analyzed, and the refinement efficiency of the AI algorithm was discussed, expected to assist clinicians in the care and treatment of patients. 100 MHD patients who were in the hospital were selected as the research subjects. They were randomly divided into the conventional DSA group (conventional group) and the AI algorithm-based DSA group (AI-based DSA group). The conventional group used conventional DSA images to guide the care of HM patients, and the AI-based DSA group used the AI algorithm to optimize DSA images. Results. It was found that the AI-based DSA group was better than the conventional DSA group in terms of image sharpness and shaded areas, and the image mean square error (MSE) loss value was smaller ( P < 0.05 ). The patients were followed up for 3 months. In the AI-based DAS group, the blood flow of the drainage vein (DV), the blood flow of the proximal vein (PA), and the blood flow of the brachial artery (BA) were greater than those of the conventional group ( P < 0.05 ). During the 3-month follow-up period, in the conventional group, thrombosis occurred in 4 patients, low-flow AVF occurred in 5 patients, high-flow AVF occurred in 3 patients, and heart failure occurred in 5 patients. In the AI-based DSA group, thrombosis occurred in 2 patients, low-flow AVF occurred in 2 cases, high-flow AVF occurred in 1 case, and heart failure occurred in 3 cases. There were no other cardiac complications in both groups. Conclusion. DSA images optimized by the AI algorithm are suitable for clinical diagnosis and have practical application value.

2006 ◽  
Vol 110 (2) ◽  
pp. 255-263 ◽  
Author(s):  
Julian M. Stewart ◽  
June L. Glover ◽  
Marvin S. Medow

POTS (postural tachycardia syndrome) is associated with low blood volume and reduced renin and aldosterone; however, the role of Ang (angiotensin) II has not been investigated. Previous studies have suggested that a subset of POTS patients with increased vasoconstriction related to decreased bioavailable NO (nitric oxide) have decreased blood volume. Ang II reduces bioavailable NO and is integral to the renin–Ang system. Thus, in the present study, we investigated the relationship between blood volume, Ang II, renin, aldosterone and peripheral blood flow in POTS patients. POTS was diagnosed by 70° upright tilt, and supine calf blood flow, measured by venous occlusion plethysmography, was used to subgroup POTS patients. A total of 23 POTS patients were partitioned; ten with low blood flow, eight with normal flow and five with high flow. There were ten healthy volunteers. Blood volume was measured by dye dilution. All biochemical measurements were performed whilst supine. Blood volume was decreased in low-flow POTS (2.14±0.12 litres/m2) compared with controls (2.76±0.20 litres/m2), but not in the other subgroups. PRA (plasma renin activity) was decreased in low-flow POTS compared with controls (0.49±0.12 compared with 0.90±0.18 ng of Ang I·ml−1·h−1 respectively), whereas plasma Ang II was increased (89±20 compared with 32±4 ng/l), but not in the other subgroups. PRA correlated with aldosterone (r=+0.71) in all subjects. PRA correlated negatively with blood volume (r=−0.72) in normal- and high-flow POTS, but positively (r=+0.65) in low-flow POTS. PRA correlated positively with Ang II (r=+0.76) in normal- and high-flow POTS, but negatively (r=−0.83) in low-flow POTS. Blood volume was negatively correlated with Ang II (r=−0.66) in normal- and high-flow POTS and in five low-flow POTS patients. The remaining five low-flow POTS patients had reduced blood volume and increased Ang II which was not correlated with blood volume. The data suggest that plasma Ang II is increased in low-flow POTS patients with hypovolaemia, which may contribute to local blood flow dysregulation and reduced NO bioavailability.


2004 ◽  
Vol 10 (1_suppl) ◽  
pp. 153-154 ◽  
Author(s):  
H. Tenjin

We investigated and compared the morphologic and haemodynamic changes between before and after stent placement when several different kinds of stents were applied to experimental aneurysms. Experimental aneurysms in eight pig carotid arteries were used. Stents were placed covering the aneurysm orifice. Five Cordis stents (coil stent), two GFXs (multilink stent), and one Multilink (tube stent) were used in this study. After stent placement, the arteries were perfused with 70% ethanol, the specimens were embedded in polyester plastic resin and thin slices were stained with hemtoxilin-eosin. Blood flow in the aneurysm was measured using digital subtraction angiography. The parent artery was stretched in multilink stent (GFX) cases, and was most markedly stretched by use of the tube stent (Multilink). Stent placement with any type of stent decreased intra-aneurysmal blood flow.


2000 ◽  
Vol 93 (4) ◽  
pp. 1085-1094 ◽  
Author(s):  
Richard N. Upton ◽  
Guy L. Ludbrook ◽  
Cliff Grant ◽  
David J. Doolette

Background Thiopental and propofol are highly lipid-soluble, and their entry into the brain often is assumed to be limited by cerebral blood flow rather than by a diffusion barrier. However, there is little direct experimental evidence for this assumption. Methods The cerebral kinetics of thiopental and propofol were examined over a range of cerebral blood flows using five and six chronically instrumented sheep, respectively. Using anesthesia (2.0% halothane), three steady state levels of cerebral blood flow (low, medium, and high) were achieved in random order by altering arterial carbon dioxide tension. For each flow state, 250 mg thiopental or 100 mg propofol was infused intravenously over 2 min. To quantify cerebral kinetics, arterial and sagittal sinus blood was sampled rapidly for 20 min from the start of the infusion, and 1.5 h was allowed between consecutive infusions. Various models of cerebral kinetics were examined for their ability to account for the data. Results The mean baseline cerebral blood flows for the "high" flow state were over threefold greater than those for the low. For the high-flow state the normalized arteriovenous concentration difference across the brain was smaller than for the low-flow state, for both drugs. The data were better described by a model with partial membrane limitation than those with only flow limitation or dispersion. Conclusions The cerebral kinetics of thiopental and propofol after bolus injection were dependent on cerebral blood flow, despite partial diffusion limitation. Higher flows produce higher peak cerebral concentrations.


1984 ◽  
Author(s):  
David K. Swanson ◽  
P.David Myerowitz ◽  
Michael S. Van Lysel ◽  
Walter W. Peppler ◽  
Barry L. Fields ◽  
...  

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