scholarly journals From the Old, the Best: Parathyroidectomy in the Management of Soft-Tissue and Vascular Calcification in Patients with Chronic Renal Disease

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
P. Mariel Hernandez ◽  
B. Daniel Enos ◽  
T. Gonzalo Labarca ◽  
A. Guillermo Vanderstelt

Introduction. Bone mineral disease in patients with chronic kidney disease (CKD-MBD) is a clinical syndrome involving bone, biochemical changes, and extraosseous calcification. These complications increase morbidity and mortality. Prevalence reports are rare. Case Report. This case shows a young woman on peritoneal dialysis (PD) for 10 years with severe secondary hyperparathyroidism and soft-tissue calcifications in the hands, pelvis, and right knee, as well as severe vascular calcification, managed with calcimimetics without success. We decided to perform subtotal parathyroidectomy (STPTX). Three months after surgery, she had satisfactory evolution, despite notable hungry bone disease, without bone pain or functional limitation and almost no calcifications. Discussion. The benefit of hemodialysis has been shown with better volume management and improvement of calcium/phosphate products. STPTX allowed biochemical control and calcification improvement, with an evident better quality of life for our patient. Therapeutic alternatives need to be tailored to the patient’s characteristics in the calcimimetics era.

Author(s):  
Abdulrahman Z. Nakshabandi ◽  
Ahamd F. Alomar ◽  
Moayad Baazeem ◽  
Abdulrahman Alosaimi ◽  
Ibrahim O. Bello

1980 ◽  
Vol 5 (4) ◽  
pp. 251-252 ◽  
Author(s):  
Andrea Meneghello ◽  
Massimo Bertoli ◽  
Gian Franco Romagnoli

2008 ◽  
Vol 25 (3) ◽  
pp. E8 ◽  
Author(s):  
Bassam Addas ◽  
Elisabeth M. S. Sherman ◽  
Walter J. Hader

Gelastic epilepsy (GE) associated with hypothalamic hamartomas (HHs) is now a well-characterized clinical syndrome consisting of gelastic seizures starting in infancy, medically refractory seizures with or without the development of multiple seizure types, and behavioral and cognitive decline. It has been postulated that the development of the HH-GE syndrome is a result of a progressive epileptic encephalopathy or secondary epileptogenesis, which is potentially reversible with treatment of the HH. A variety of surgical options for the treatment of HHs exist, including open and endoscopic procedures, radiosurgery, interstitial radiotherapy, and stereotactic radiofrequency thermocoagulation. Surgical treatment can result in seizure freedom in up to 50% of patients and can be accompanied by significant improvements in behavior, cognition, and quality of life. Partial treatment of HHs may be sufficient to reduce seizure frequency and improve behavior and quality of life with less risk. A component of reversible cognitive dysfunction may be present in some patients with an HH-GE syndrome.


2021 ◽  
pp. 1-11
Author(s):  
Silvia Bernuth ◽  
Michael Jakubietz ◽  
Christoph Isbert ◽  
Joachim Reibetanz ◽  
Rainer Meffert ◽  
...  

BACKGROUND: Preservation of quality of life regarding fecal continence after abdominoperineal excision (APE) in cancer is challenging. Simultaneous soft tissue coverage and restoration of continence mechanism can be provided through an interdisciplinary collaboration of colorectal and plastic reconstructive surgery. OBJECTIVE: Evaluation of surgical procedure and outcome combining soft tissue reconstruction using a central perforated vertical rectus abdominis myocutaneous flap (VRAM), implementing a perineostoma and restoring anorectal angle augmenting the levator ani by neurostimulated graciloplasty. METHODS: 14 Patients underwent APE due to cancer. In all patients coverage was achieved by pedicled VRAM and simultaneous pull-through descendostomy (perineostoma). 10 of those patients received a levator augmentation additionally. Postoperative complications, functional measures of continence as well as quality of life were obtained. RESULTS: Perineal minor complication rate was 43% without need of surgical intervention. All but one VRAM survived. Continence measures and disease specific life quality showed a good preservation of continence in most patients. CONCLUSION: The results present a complex therapy option accomplished by a collaboration of two highly specialized partners (visceral and plastic surgery) after total loss of the sphincter function and consecutive fecal insufficiency after APE.


2017 ◽  
Vol 25 (5) ◽  
pp. 202-205 ◽  
Author(s):  
MARCELO JOSÉ CORTEZ BEZERRA ◽  
IGOR MAGALHÃES BARBOSA ◽  
THALES GONÇALVES DE SOUSA ◽  
LARISSA MEIRELES FERNANDES ◽  
DIEGO LEONARDO MENEZES MAIA ◽  
...  

ABSTRACT Objective: To describe the epidemiological profile, presented deformities, associated comorbidities, and impact on quality of life in patients with knee osteoarthritis. This study was conducted in a philanthropic hospital in Fortaleza from 2014 to 2015. Methods: Data were collected from medical records, epidemiological forms, and by applying the Lequesne index questionnaire, which contains several questions related to pain, discomfort and functional limitation to assess the severity of symptoms. Results: Females were more prevalent (76.7%), as were patients over 65 years of age (61.6%) and non-whites (81.6%). As for comorbidities, 83.3% had hypertension and 31.7% had diabetes. Of the total, 76.5% cases were genu varum, and 23.5% genu valgum. According to the Lequesne index findings, 61.6% cases were “extremely severe,” and women had higher scores. Conclusion: Females were more prevalent and whites were less prevalent. The most frequent comorbidity was hypertension. Female and elderly patients have more severe disease according to Lequesne index score, and these findings were statistically significant. Level of Evidence II, Prospective Study.


2013 ◽  
Vol 16 (2) ◽  
pp. 328-337 ◽  
Author(s):  
Camila Mello dos Santos ◽  
Fernando Neves Hugo ◽  
Andréa Fachel Leal ◽  
Juliana Balbinot Hilgert

Objective: To investigate if there is convergent validity between the dimensions of the World Health Organization Quality of Life Questionnaire-Brief Version (WHOQOL-Bref) and the Oral Health Impact Profile-14 (OHIP-14) questionnaire. Methods: In this cross-sectional study, a random sample of 872 elderly Southern-Brazilians was evaluated. Questionnaires assessing socio-demographic data and quality of life in general (WHOQOL-Bref) and oral health-related quality of life (OHIP-14) were used. Analysis of the WHOQOL-Bref and OHIP-14 questionnaires used descriptive statistics. The dimensions of the WHOQOL-Bref and OHIP-14 questionnaires were correlated by affinity. The convergence between WHOQOL-Bref and OHIP-14 dimensions was analyzed by Spearman’s correlation coefficients. Results: The social relations dimension of the WHOQOL-Bref presented the greatest mean (18.24 ± 2.30). The physical pain dimension of the OHIP-14 presented a median of 1.0 (0.0 – 3.0). All correlations between the WHOQOL-Bref and OHIP-14 dimensions were significant, negative and associated with a low magnitude. The correlation between WHOQOL-physical and OHIP-functional limitation, OHIP-physical pain, OHIP-physical disability and OHIP-handicap were – 0.164, – 0.262, – 0.196 and – 0.125 respectively. WHOQOL-psychological was associated with OHIP-psychological discomfort and OHIP-psychological disability, and WHOQOL-social showed an association with OHIP-social disability. Conclusions: All correlations analyzed had a positive association of low magnitude. Despite the fact that the WHOQOL-Bref and OHIP-14 instruments have related dimensions, they measure physical, psychological and social relations differently.


2003 ◽  
Vol 60 (3) ◽  
pp. 365-368
Author(s):  
Ljubisa Dzambas ◽  
Asen Dzolev

This paper presents a combined surgical-prosthetic procedure of reconstructing mandibular bone defect in a 53 year old patient, following enucleation of a mandibular cyst (Cystectomy Partsch II). After a thorough diagnostic evaluation, a surgical procedure was planned with the particular attention to the nature of the disease, patient?s condition, size and extension of the cyst, tissue loss, and the possibilities of prosthetic management of a mandibular bone defect with partial postresection dental prosthesis. It is of great importance to point to the significance of teamwork of a maxillofacial surgeon and a specialist in prosthodontics. This kind of cooperation provided very effective and less risky soft tissue, as well as bone tissue regeneration (osteogenesis). The patient?s recovery was fast, and he could return to his daily activities and work without significant changes regarding quality of life after surgery and prosthetic treatment.


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