scholarly journals The Effect of Improving Preoperative Sleep Quality on Perioperative Pain by Zolpidem in Patients Undergoing Laparoscopic Colorectal Surgery: A Prospective, Randomized Study

2022 ◽  
Vol 2022 ◽  
pp. 1-9
Author(s):  
Zhennan Xiao ◽  
Bo Long ◽  
Zeji Zhao
Keyword(s):  
Postoperative Pain ◽  
Colorectal Surgery ◽  
Sleep Quality ◽  
Surgical Procedure ◽  
Laparoscopic Colorectal Surgery ◽  
Randomized Study ◽  
Nausea And Vomiting ◽  
Prospective Randomized Study ◽  
Ample Evidence ◽  
Vas Scores

Background and Objectives. Opioids are essential in pain management after laparoscopic colorectal surgery while large dose may induce constipation and pneumonia. Ample evidence has demonstrated that postoperative analgesia can improve sleep quality. But the effects of improvement in sleep quality on postoperative pain have yet to be determined. The aim of this study was to investigate the effect of improving preoperative sleep quality by zolpidem on intraoperative analgesia and postoperative pain. Methods. A prospective, randomized study was conducted with 88 patients undergoing laparoscopic colorectal surgery. The experimental group (S group, n = 44) was given 10 mg of zolpidem tartrate one night before the surgical procedure, while no medication was given to the control group (C group, n = 44). The primary outcome was the intraoperative remifentanil consumption. Sufentanil consumption, average patient-controlled analgesia (PCA) effective press times, the visual analog scale (VAS) scores, and incidences of postoperative nausea and vomiting (PONV) were recorded at 6 h (T1), 12 h (T2), and 24 h (T3) postoperatively. Results. The intraoperative remifentanil consumption was significantly lower in the S group than that in the C group ( p < 0.01 ). Sufentanil consumption at 6 h and 12 h postoperatively was significantly lower in the S group than that in the C group ( p < 0.05 ); average PCA effective press times and VAS scores, at 6 h and 12 h postoperatively, were significantly lower in the S group than those in the C group ( p < 0.01 ); differences between groups 24 h postoperatively were not significant. No significant between-group difference was noted in the incidence of nausea and vomiting. Conclusion. Improving patients’ sleep quality the night before surgical procedure by zolpidem can decrease the usage of intraoperative analgesics and reduce postoperative pain.

Prospective randomized study on perioperative enteral immunonutrition in laparoscopic colorectal surgery

2007 ◽  
Vol 21 (7) ◽  
pp. 1175-1179 ◽  
Author(s):  
C. Finco ◽  
P. Magnanini ◽  
G. Sarzo ◽  
M. Vecchiato ◽  
B. Luongo ◽  
...  
Keyword(s):  
Colorectal Surgery ◽  
Laparoscopic Colorectal Surgery ◽  
Randomized Study ◽  
Prospective Randomized Study

770 POSTOPERATIVE PAIN AFTER PURE AND ROBOT-ASSISTED LAPAROSCOPIC RADICAL PROSTATECTOMY. A PROSPECTIVE RANDOMIZED STUDY

2011 ◽  
Vol 185 (4S) ◽  
Author(s):  
Eliana Calza ◽  
Francesco Porpiglia ◽  
Cristian Fiori ◽  
Andrea Giannone ◽  
Alessandro Meli ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Radical Prostatectomy ◽  
Randomized Study ◽  
Laparoscopic Radical Prostatectomy ◽  
Prospective Randomized Study ◽  
Robot Assisted

scholarly journals A multicentre, prospective, observational cohort study of variation in practice in perioperative analgesia strategies in elective laparoscopic colorectal surgery (the LapCoGesic study)

2020 ◽  
Vol 102 (1) ◽  
pp. 28-35
Author(s):  
L Brown ◽  
M Gray ◽  
B Griffiths ◽  
M Jones ◽  
A Madhavan ◽  
...  
Keyword(s):  
Postoperative Pain ◽  
Colorectal Surgery ◽  
Outcome Measure ◽  
Enhanced Recovery ◽  
Laparoscopic Colorectal Surgery ◽  
Patient Controlled Analgesia ◽  
Thoracic Epidural ◽  
Pain Scores ◽  
Patient Reported ◽  
Observational Cohort

Introduction Enhanced recovery programmes are established as an essential part of laparoscopic colorectal surgery. Optimal pain management is central to the success of an enhanced recovery programme and is acknowledged to be an important patient reported outcome measure. A variety of analgesia strategies are employed in elective laparoscopic colorectal surgery ranging from patient-controlled analgesia to local anaesthetic wound infiltration catheters. However, there is little evidence regarding the optimal analgesia strategy in this cohort of patients. The LapCoGesic study aimed to explore differences in analgesia strategies employed for patients undergoing elective laparoscopic colorectal surgery and to assess whether this variation in practice has an impact on patient-reported and clinical outcomes. Materials and methods A prospective, multicentre, observational cohort study of consecutive patients undergoing elective laparoscopic colorectal resection was undertaken over a two-month period. The primary outcome measure was postoperative pain scores at 24 hours. Data analysis was conducted using SPSS version 22. Results A total of 103 patients undergoing elective laparoscopic colorectal surgery were included in the study. Thoracic epidural was used in 4 (3.9%) patients, spinal diamorphine in 56 (54.4%) patients and patient-controlled analgesia in 77 (74.8%) patients. The use of thoracic epidural and spinal diamorphine were associated with lower pain scores on day 1 postoperatively (P < 0.05). The use of patient-controlled analgesia was associated with significantly higher postoperative pain scores and pain severity. Discussion Postoperative pain is managed in a variable manner in patients undergoing elective colorectal surgery, which has an impact on patient reported outcomes of pain scores and pain severity.

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