scholarly journals Protective Effects of Low Calcium Intake and Low Calcium Absorption Vitamin D Receptor Genotype in the California Collaborative Prostate Cancer Study

2012 ◽  
Vol 22 (1) ◽  
pp. 16-24 ◽  
Author(s):  
Glovioell W. Rowland ◽  
Gary G. Schwartz ◽  
Esther M. John ◽  
Sue Ann Ingles
2007 ◽  
Vol 98 (5) ◽  
pp. 878-881 ◽  
Author(s):  
Hee-Seon Kim ◽  
Ji-Sun Kim ◽  
Nam Soo Kim ◽  
Jin Ho Kim ◽  
Byung-Kook Lee

This study investigated the associations among vitamin D receptor (VDR)BsmI polymorphism, calcium intake and bone strength as indicated by the broadband ultrasound attenuation (BUA) measured by calcaneal quantitative ultrasound at the left calcaneus in community-dwelling subjects with a low calcium intake. The VDRBsmI polymorphism was analysed in 335 women older than 65 years residing in rural Asan, Korea. Calcium intake was assessed with a 2 d, 24 h recall method. The distribution of genotypes was similar to that reported in other Asian populations (92 % bb, 7 % Bb and 1 % BB). The calcaneal BUA was significantly higher (P = 0·013) in the bb genotype than in the Bb or BB genotype (Bb and BB genotypes were combined due to the small number of BB subjects) in a multiple regression model after adjusting for age, body weight, height, physical activity and nutritional factors. BUA was not significantly affected by the calcium intake regardless of the genotype, cross-sectionally. The energy-adjusted average calcium intake of this population was 439·6 mg/d (432·5 mg/d for bb and 522·3 mg/d for Bb or BB), and 96 % of the subjects had dietary intakes that were less than the recommended Dietary Reference Intake for Koreans (which for calcium is 800 mg/d for women older than 65 years). In summary, the BUA in older Korean women with a low calcium intake was significantly influenced by the VDR genotype but not by the calcium intake, cross-sectionally.


2010 ◽  
Vol 121 (1-2) ◽  
pp. 117-120 ◽  
Author(s):  
Frederic Jehan ◽  
Alexandru Voloc ◽  
Laure. Esterle ◽  
Odile Walrant-Debray ◽  
Thi-Minh Nguyen ◽  
...  

2006 ◽  
Vol 175 (4S) ◽  
pp. 260-260
Author(s):  
Nicholas J. Rukin ◽  
Samuel J. Moon ◽  
Dhaval Bodiwala ◽  
Christopher J. Luscombe ◽  
Mark F. Saxby ◽  
...  

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