International Variation in Female Breast Cancer Incidence and Mortality Rates

Abstract PURPOSE: Breast cancer is the leading cause of death in females around the world. Its occurrence and development has been linked to genetic factors, living habits and health conditions, but also by socioeconomic factors. Comparisons of incidence and mortality rates of female breast cancer are useful approaches to define cancer-related socioeconomic disparities. METHODS: International Agency for Research on Cancer's CANCERMondial clearinghouse was used to determine the incidence and mortality rates of female breast cancer data from several developed countries for 1980–2012. We subsequently investigated the effects of socioeconomic factors on breast cancer incidence and mortality rates by regression methods from univariate analysis to path diagram analysis. RESULTS: The relationship between socioeconomic factors and the occurrence and development of breast cancer did not follow a monotonic function. We found a positive, significant association of national public wealth (GDP) on the incidence and mortality of breast cancer. The path coefficients in the structuralequations model are -0.51 and -0.39, respectively. In addition to the significant relationship between individual physical and psychological characteristics, social pressure, such as unemployment rate (UR) has a significant impact on the incidence and mortality of breast cancer. The path coefficients in the structural equations model are all 0.2. The path coefficients of individual economic wealth to the incidence rate and mortality rate of breast cancer is 0.18 and 0.27, respectively. CONCLUSIONS: A significant statistical relationship between the socioeconomic development and the crude rates of female breast cancer was shown in this study. The incidence and mortality rates of breast cancer can be regulated effectively by a moderate increase in GDP, and clearly was affected by the individual’s economic wealth (GDPPC). In addition, the influence of social pressure (e.g., unemployment rate) on the incidence and mortality of breast cancer was not typical monotonous. The survival rate of breast cancer determined by the ratio of mortality rate to incidence rate also showed a similar pattern with socioeconomic factors.

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Comparison of Male and Female Breast Cancer Incidence and Mortality Trends in Central Serbia

Asian Pacific Journal of Cancer Prevention ◽

10.7314/apjcp.2013.14.10.5681 ◽

2013 ◽

Vol 14 (10) ◽

pp. 5681-5685 ◽

Cited By ~ 2

Author(s):

Sandra Sipetic-Grujicic ◽

Zafir Murtezani ◽

Isidora Ratkov ◽

Anita Grgurevic ◽

Jelena Marinkovic ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Incidence ◽

Breast Cancer Incidence ◽

Female Breast Cancer ◽

Mortality Trends ◽

Male And Female ◽

Female Breast ◽

Incidence And Mortality

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The changing global patterns of female breast cancer incidence and mortality

Breast Cancer Research ◽

10.1186/bcr932 ◽

2004 ◽

Vol 6 (6) ◽

Cited By ~ 493

Author(s):

Freddie Bray ◽

Peter McCarron ◽

D Maxwell Parkin

Keyword(s):

Breast Cancer ◽

Cancer Incidence ◽

Breast Cancer Incidence ◽

Female Breast Cancer ◽

Female Breast ◽

Incidence And Mortality ◽

Global Patterns

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Inequalities in the burden of female breast cancer in Brazil, 1990–2017

Population Health Metrics ◽

10.1186/s12963-020-00212-5 ◽

2020 ◽

Vol 18 (S1) ◽

Author(s):

Maximiliano Ribeiro Guerra ◽

Mário Círio Nogueira ◽

Deborah Carvalho Malta ◽

Camila Soares Lima Côrrea ◽

Maria de Fatima Marinho de Souza ◽

...

Keyword(s):

Breast Cancer ◽

Incidence Rate ◽

Cancer Incidence ◽

Breast Cancer Incidence ◽

Female Breast Cancer ◽

Diagnostic Methods ◽

Cancer Death ◽

Female Breast ◽

Life Years ◽

Incidence And Mortality

Abstract Background Breast cancer is the most frequently diagnosed cancer in women and the leading cause of cancer death among females worldwide. In recent decades, breast cancer death rates have been stable or decreasing in more developed regions; however, this has not been observed in less developed regions. This study aims to evaluate inequalities in the burden of female breast cancer in Brazil including an analysis of interregional and interstate patterns in incidence, mortality and disability-adjusted life years (DALYs) rates from 1990 to 2017, and mortality-to-incidence ratio (MIR), and their association with the Socio-demographic Index (SDI). Methods Using estimates from the global burden of disease (GBD) study, we applied a spatial exploratory analysis technique to obtain measurements of global and local spatial correlation. Percentage changes of breast cancer incidence, mortality, and DALYs rates between 1990 and 2017 were calculated, and maps were developed to show the spatial distribution of the variables. Spatial panel models were adjusted to investigate the association between rates and SDI in Brazilian states. Results In Brazil, while breast cancer mortality rate have had modest reduction (−4.45%; 95% UI: −6.97; −1.76) between 1990 and 2017, the incidence rate increased substantially (+39.99%; 95% UI: 34.90; 45.39). Breast cancer incidence and mortality rates in 1990 and 2017 were higher in regions with higher SDI, i.e., the most developed ones. While SDI increased in all Brazilian states between 1990 and 2017, notably in less developed regions, MIR decreased, more notably in more developed regions. The SDI had a positive association with incidence rate and a negative association with MIR. Conclusion Such findings suggest an improvement in breast cancer survival in the period, which may be related to a broader access to diagnostic methods and treatment. This study also revealed the inequality in breast cancer outcomes among Brazilian states and may guide public policy priorities for disease control in the country.

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