A Randomized Trial of Ex vivo CD40L Activation of a Dendritic Cell Vaccine in Colorectal Cancer Patients: Tumor-Specific Immune Responses Are Associated with Improved Survival

Richard J. Barth; Dawn A. Fisher; Paul K. Wallace; Jacqueline Y. Channon; Randolph J. Noelle; Jiang Gui; Marc S. Ernstoff

doi:10.1158/1078-0432.ccr-10-2138

A Randomized Trial of Ex vivo CD40L Activation of a Dendritic Cell Vaccine in Colorectal Cancer Patients: Tumor-Specific Immune Responses Are Associated with Improved Survival

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-10-2138 ◽

2010 ◽

Vol 16 (22) ◽

pp. 5548-5556 ◽

Cited By ~ 57

Author(s):

Richard J. Barth ◽

Dawn A. Fisher ◽

Paul K. Wallace ◽

Jacqueline Y. Channon ◽

Randolph J. Noelle ◽

...

Keyword(s):

Colorectal Cancer ◽

Dendritic Cell ◽

Immune Responses ◽

Randomized Trial ◽

Cancer Patients ◽

Ex Vivo ◽

Dendritic Cell Vaccine ◽

Cell Vaccine ◽

Colorectal Cancer Patients

Download Full-text

A Randomized Trial of Ex vivo CD40L Activation of a Dendritic Cell Vaccine in Colorectal Cancer Patients: Tumor-Specific Immune Responses Are Associated with Improved Survival

Yearbook of Surgery ◽

10.1016/j.ysur.2011.04.087 ◽

2012 ◽

Vol 2012 ◽

pp. 318-320

Author(s):

T.J. Eberlein

Keyword(s):

Colorectal Cancer ◽

Dendritic Cell ◽

Immune Responses ◽

Randomized Trial ◽

Cancer Patients ◽

Ex Vivo ◽

Dendritic Cell Vaccine ◽

Cell Vaccine ◽

Colorectal Cancer Patients

Download Full-text

Treatment of Metastatic Colorectal Cancer Patients with a Tumor Lysate Pulsed Dendritic Cell Vaccine: A Randomized Evaluation of Ex Vivo CD40L Activation

Journal of Immunotherapy ◽

10.1097/00002371-200411000-00073 ◽

2004 ◽

Vol 27 (6) ◽

pp. S20

Author(s):

Richard Barch ◽

Paul Wallace ◽

Dawn Fischer ◽

Jacqueline Smith ◽

Randolph Noelle

Keyword(s):

Colorectal Cancer ◽

Dendritic Cell ◽

Metastatic Colorectal Cancer ◽

Cancer Patients ◽

Ex Vivo ◽

Dendritic Cell Vaccine ◽

Cell Vaccine ◽

Tumor Lysate ◽

Randomized Evaluation ◽

Colorectal Cancer Patients

Download Full-text

Clinical Benefit of Allogeneic Melanoma Cell Lysate-Pulsed Autologous Dendritic Cell Vaccine in MAGE-Positive Colorectal Cancer Patients

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-09-1537 ◽

2009 ◽

Vol 15 (24) ◽

pp. 7726-7736 ◽

Cited By ~ 32

Author(s):

H. C. Toh ◽

W.-W. Wang ◽

W. K. Chia ◽

P. Kvistborg ◽

L. Sun ◽

...

Keyword(s):

Colorectal Cancer ◽

Dendritic Cell ◽

Cancer Patients ◽

Melanoma Cell ◽

Clinical Benefit ◽

Dendritic Cell Vaccine ◽

Cell Vaccine ◽

Autologous Dendritic Cell ◽

Cell Lysate ◽

Colorectal Cancer Patients

Download Full-text

Comprehensive immunological analyses of colorectal cancer patients in the phase I/II study of quickly matured dendritic cell vaccine pulsed with carcinoembryonic antigen peptide

Cancer Immunology Immunotherapy ◽

10.1007/s00262-011-1051-1 ◽

2011 ◽

Vol 60 (11) ◽

pp. 1565-1575 ◽

Cited By ~ 28

Author(s):

Mitsuru Sakakibara ◽

Tatsuya Kanto ◽

Michiyo Hayakawa ◽

Shoko Kuroda ◽

Hideki Miyatake ◽

...

Keyword(s):

Colorectal Cancer ◽

Dendritic Cell ◽

Phase I ◽

Carcinoembryonic Antigen ◽

Cancer Patients ◽

Dendritic Cell Vaccine ◽

Cell Vaccine ◽

Antigen Peptide ◽

Colorectal Cancer Patients

Download Full-text

442P A phase I-II multicenter trial with avelumab plus autologous dendritic cell vaccine in pre-treated mismatch repair-proficient (MSS) metastatic colorectal cancer patients. GEMCAD 16-02 (AVEVAC trial)

Annals of Oncology ◽

10.1016/j.annonc.2021.08.963 ◽

2021 ◽

Vol 32 ◽

pp. S555

Author(s):

M. Español-Rego ◽

C. Fernández-Martos ◽

M.E. Elez Fernandez ◽

C. Foguet ◽

L. Pedrosa ◽

...

Keyword(s):

Colorectal Cancer ◽

Dendritic Cell ◽

Phase I ◽

Cancer Patients ◽

Mismatch Repair ◽

Dendritic Cell Vaccine ◽

Multicenter Trial ◽

Cell Vaccine ◽

Autologous Dendritic Cell ◽

Colorectal Cancer Patients

Download Full-text

Abstract 2400: Treatment of colorectal cancer patients after resection of metastases with a tumor lysate pulsed dendritic cell vaccine: association between immune response and recurrence free survival

10.1158/1538-7445.am10-2400 ◽

2010 ◽

Author(s):

Richard J. Barth ◽

Dawn A. Fischer ◽

Jacqueline Y. Channon ◽

Marc Ernstoff ◽

Paul K. Wallace

Keyword(s):

Colorectal Cancer ◽

Immune Response ◽

Dendritic Cell ◽

Dendritic Cell Vaccine ◽

Cell Vaccine ◽

Recurrence Free Survival ◽

Tumor Lysate ◽

Free Survival ◽

Resection Of Metastases ◽

Colorectal Cancer Patients

Download Full-text

Phase II randomized trial of autologous tumor lysate dendritic cell vaccine (ADC) plus best supportive care (BSC) compared with BSC, in pre-treated advanced colorectal cancer patients.

Journal of Clinical Oncology ◽

10.1200/jco.2015.33.15_suppl.3048 ◽

2015 ◽

Vol 33 (15_suppl) ◽

pp. 3048-3048 ◽

Cited By ~ 5

Author(s):

Joan Maurel ◽

Miguel Caballero-Baños ◽

Jordi Mila ◽

Jaime Tabera ◽

Sara Varea ◽

...

Keyword(s):

Colorectal Cancer ◽

Dendritic Cell ◽

Supportive Care ◽

Advanced Colorectal Cancer ◽

Dendritic Cell Vaccine ◽

Best Supportive Care ◽

Cell Vaccine ◽

Autologous Tumor ◽

Tumor Lysate ◽

Colorectal Cancer Patients

Download Full-text

Author's reply to: “Prognostic value of cetuximab related skintoxicity in metastatic colorectal cancer patients and its correlation with parameters of the EGFR signal transduction pathway: Results from a randomized trial of the GERMAN AIO CRC Study Group”

International Journal of Cancer ◽

10.1002/ijc.27804 ◽

2012 ◽

Vol 132 (7) ◽

pp. 1719-1720

Author(s):

Sebastian Stintzing ◽

Volker Heinemann

Keyword(s):

Colorectal Cancer ◽

Signal Transduction ◽

Metastatic Colorectal Cancer ◽

Randomized Trial ◽

Cancer Patients ◽

Prognostic Value ◽

Signal Transduction Pathway ◽

Study Group ◽

Transduction Pathway ◽

Colorectal Cancer Patients

Download Full-text

Vaccination of colorectal cancer patients with TroVax given alongside chemotherapy (5-fluorouracil, leukovorin and irinotecan) is safe and induces potent immune responses

Cancer Immunology Immunotherapy ◽

10.1007/s00262-007-0428-7 ◽

2007 ◽

Vol 57 (7) ◽

pp. 977-986 ◽

Cited By ~ 63

Author(s):

Richard Harrop ◽

Noel Drury ◽

William Shingler ◽

Priscilla Chikoti ◽

Irina Redchenko ◽

...

Keyword(s):

Colorectal Cancer ◽

Immune Responses ◽

Cancer Patients ◽

Colorectal Cancer Patients

Download Full-text

Tumour cell lysate-loaded dendritic cell vaccine induces biochemical and memory immune response in castration-resistant prostate cancer patients

British Journal of Cancer ◽

10.1038/bjc.2013.494 ◽

2013 ◽

Vol 109 (6) ◽

pp. 1488-1497 ◽

Cited By ~ 39

Author(s):

D Reyes ◽

L Salazar ◽

E Espinoza ◽

C Pereda ◽

E Castellón ◽

...

Keyword(s):

Prostate Cancer ◽

Immune Response ◽

Dendritic Cell ◽

Cancer Patients ◽

Dendritic Cell Vaccine ◽

Cell Vaccine ◽

Castration Resistant Prostate Cancer ◽

Cell Lysate ◽

Castration Resistant ◽

Memory Immune Response

Download Full-text