Noninvasive Detection of Microsatellite Instability and High Tumor Mutation Burden in Cancer Patients Treated with PD-1 Blockade

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-19-1372 ◽

2019 ◽

Vol 25 (23) ◽

pp. 7024-7034 ◽

Author(s):

Andrew Georgiadis ◽

Jennifer N. Durham ◽

Laurel A. Keefer ◽

Bjarne R. Bartlett ◽

Magdalena Zielonka ◽

...

Keyword(s):

Microsatellite Instability ◽

Cancer Patients ◽

Noninvasive Detection ◽

Tumor Mutation Burden ◽

Mutation Burden

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A comprehensive pan-cancer analysis of CD274 gene amplification, tumor mutation burden, microsatellite instability, and PD-L1 expression in Chinese cancer patients

Annals of Translational Medicine ◽

10.21037/atm-21-853 ◽

2021 ◽

Vol 9 (8) ◽

pp. 677-677

Author(s):

Guanghui Gao ◽

Xiao-Dong Zhang ◽

Hu Qu ◽

Bing Yao ◽

Yuxi Zhou ◽

...

Keyword(s):

Microsatellite Instability ◽

Cancer Patients ◽

Gene Amplification ◽

Tumor Mutation Burden ◽

Mutation Burden ◽

Chinese Cancer Patients ◽

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Identification of ovarian cancer patients for immunotherapy by concurrent assessment of tumor mutation burden (TMB), microsatellite instability (MSI) status, and targetable genomic alterations (GA)

Gynecologic Oncology ◽

10.1016/j.ygyno.2018.04.081 ◽

2018 ◽

Vol 149 ◽

pp. 36 ◽

Author(s):

J. Feinberg ◽

J.A. Elvin ◽

S. Bellone ◽

A.D. Santin

Keyword(s):

Ovarian Cancer ◽

Microsatellite Instability ◽

Cancer Patients ◽

Genomic Alterations ◽

Tumor Mutation Burden ◽

Mutation Burden ◽

Concurrent Assessment

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Blood tumor mutation burden can predict the clinical response to immune checkpoint inhibitors in advanced non-small cell lung cancer patients

Cancer Immunology Immunotherapy ◽

10.1007/s00262-021-02943-2 ◽

2021 ◽

Author(s):

Xi Chen ◽

Liangjie Fang ◽

Yanping Zhu ◽

Zhang Bao ◽

Qing Wang ◽

...

Keyword(s):

Lung Cancer ◽

Cancer Patients ◽

Immune Checkpoint ◽

Immune Checkpoint Inhibitors ◽

Checkpoint Inhibitors ◽

Small Cell Lung ◽

Tumor Mutation Burden ◽

Lung Cancer Patients ◽

Mutation Burden

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Mucin 4 mutation is associated with tumor mutation burden and promotes antitumor immunity in colon cancer patients

Aging ◽

10.18632/aging.202756 ◽

2021 ◽

Author(s):

Linglong Peng ◽

Yang Li ◽

Haitao Gu ◽

Ling Xiang ◽

Yongfu Xiong ◽

...

Keyword(s):

Colon Cancer ◽

Cancer Patients ◽

Antitumor Immunity ◽

Tumor Mutation Burden ◽

Mutation Burden

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Tumor Mutation Burden Prediction Model in Egyptian Breast Cancer patients based on Next Generation Sequencing

Asian Pacific Journal of Cancer Prevention ◽

10.31557/apjcp.2021.22.7.2053 ◽

2021 ◽

Vol 22 (7) ◽

pp. 2053-2059

Author(s):

Auhood Nassar ◽

Ahmed Lymona ◽

Mai Lotfy ◽

Amira Youssef ◽

Marwa Mohanad ◽

...

Keyword(s):

Breast Cancer ◽

Next Generation Sequencing ◽

Prediction Model ◽

Cancer Patients ◽

Next Generation ◽

Breast Cancer Patients ◽

Tumor Mutation Burden ◽

Mutation Burden ◽

Generation Sequencing

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Therapy Implications of DNA Mismatch Repair Deficiency, Microsatellite Instability, and Tumor Mutation Burden

Advances in Molecular Pathology ◽

10.1016/j.yamp.2018.07.010 ◽

2018 ◽

Vol 1 (1) ◽

pp. 193-208

Author(s):

Maryam Shirazi ◽

Antonia R. Sepulveda

Keyword(s):

Microsatellite Instability ◽

Mismatch Repair ◽

Dna Mismatch Repair ◽

Mismatch Repair Deficiency ◽

Tumor Mutation Burden ◽

Dna Mismatch ◽

Repair Deficiency ◽

Mutation Burden ◽

Dna Mismatch Repair Deficiency

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Characterization of gene expression profiles of esophageal cancer patients with different nonsynonymous tumor mutation burden

Thoracic Cancer ◽

10.1111/1759-7714.13537 ◽

2020 ◽

Vol 11 (8) ◽

pp. 2270-2278

Author(s):

Jiawei Li ◽

Haiqing Chen ◽

Haifa Guo ◽

Mantang Qiu ◽

Fan Yang

Keyword(s):

Gene Expression ◽

Esophageal Cancer ◽

Cancer Patients ◽

Expression Profiles ◽

Gene Expression Profiles ◽

Tumor Mutation Burden ◽

Mutation Burden

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Association of LRP1B Mutation With Tumor Mutation Burden and Outcomes in Melanoma and Non-small Cell Lung Cancer Patients Treated With Immune Check-Point Blockades

Frontiers in Immunology ◽

10.3389/fimmu.2019.01113 ◽

2019 ◽

Vol 10 ◽

Author(s):

Hao Chen ◽

Wei Chong ◽

Qian Wu ◽

Yueliang Yao ◽

Min Mao ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cancer Patients ◽

Cell Lung Cancer ◽

Check Point ◽

Small Cell Lung ◽

Tumor Mutation Burden ◽

Lung Cancer Patients ◽

Mutation Burden

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P2.03-28 A 500-Gene Panel to Detect Tumor Mutation Burden of Tissue and Plasma Samples from Lung Cancer Patients

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2019.08.1475 ◽

2019 ◽

Vol 14 (10) ◽

pp. S694

Author(s):

S. Xiao ◽

R. Mao ◽

R. Lin ◽

T. Wang

Keyword(s):

Lung Cancer ◽

Cancer Patients ◽

Plasma Samples ◽

Tumor Mutation Burden ◽

Lung Cancer Patients ◽

Mutation Burden

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Immunotherapy (IO) versus targeted therapy triage in endometrial adenocarcinoma (EA) by concurrent assessment of tumor mutation burden (TMB), microsatellite instability (MSI) status, and targetable genomic alterations (GA).

Journal of Clinical Oncology ◽

10.1200/jco.2016.34.15_suppl.5591 ◽

2016 ◽

Vol 34 (15_suppl) ◽

pp. 5591-5591 ◽

Author(s):

Alessandro Santin ◽

Kathleen N. Moore ◽

Camille Gunderson ◽

Kyle Gowen ◽

David Fabrizio ◽

...

Keyword(s):

Targeted Therapy ◽

Microsatellite Instability ◽

Endometrial Adenocarcinoma ◽

Genomic Alterations ◽

Tumor Mutation Burden ◽

Mutation Burden ◽

Concurrent Assessment

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